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Two-year treatment-free sustained remission after chemo-immunotherapy in a 52-year-old male with recurrent ARID1A-mutant lung adenocarcinoma: a case report

   
@article{TLCR116520,
	author = {Pedro Gonzalez Santa-Catalina and Daniel Morchón-Araujo and Marta Rodríguez-González and José María Sayagués and Mar Abad and Lorena Bellido-Hernández and Emilio Fonseca-Sánchez and Alejandro Olivares-Hernández and Edel del Barco-Morillo},
	title = {Two-year treatment-free sustained remission after chemo-immunotherapy in a 52-year-old male with recurrent ARID1A-mutant lung adenocarcinoma: a case report},
	journal = {Translational Lung Cancer Research},
	volume = {15},
	number = {4},
	year = {2026},
	keywords = {},
	abstract = {Immune checkpoint inhibitors (ICIs) have reshaped the management of advanced non-small cell lung cancer (NSCLC), yet only a subset of patients derive durable benefit and reliable predictive biomarkers remain limited. AT-rich interaction domain 1A (ARID1A) alterations have been identified as potential modulators of tumor immunogenicity, although clinical evidence of durable benefit in NSCLC remains limited. We report a case of sustained and complete remission following chemo-immunotherapy in a patient with ARID1A-mutant lung adenocarcinoma treated at the time of locoregional recurrence.},
	issn = {2226-4477},	url = {https://tlcr.amegroups.org/article/view/116520}
}