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Timing of definitive pleural intervention within systemic anticancer therapy in malignant pleural effusion from high-response lung cancers: a retrospective single-center cohort study

   
@article{TLCR116523,
	author = {Ana Pardessus Otero and Sergio Martínez-Recio and Albert Rafecas-Codern and Génesis Parada Pérez and Joel Lakhani Lakhani and Carlos Reyes and Ángel Fernández i Rebollo and Havid Jesús Colina Beltrán and Andrés Barba Joaquín and Margarita Majem and Juan Carlos Trujillo and Elisabeth Martínez and Pere Serra-Mitjà and Virginia Pajares},
	title = {Timing of definitive pleural intervention within systemic anticancer therapy in malignant pleural effusion from high-response lung cancers: a retrospective single-center cohort study},
	journal = {Translational Lung Cancer Research},
	volume = {15},
	number = {4},
	year = {2026},
	keywords = {},
	abstract = {Malignant pleural effusion (MPE) is a common and serious complication of advanced lung cancer. Although guidelines recommend early definitive intervention, the optimal timing of talc pleurodesis-based definitive intervention in pharmacologically sensitive tumors remains undefined. This study aimed to evaluate whether early pleural intervention (EPI) is associated with MPE control and clinical outcomes in lung cancers with high-response systemic therapies, and to define a clinically meaningful time threshold for EPI.},
	issn = {2226-4477},	url = {https://tlcr.amegroups.org/article/view/116523}
}