@article{TLCR11855,
author = {Ping Zhan and Qing-Qing Zhu and Ying-Ying Miu and Ya-Fang Liu and Xiao-Xia Wang and Ze-Jun Zhou and Jia-Jia Jin and Qian Li and Shinji Sasada and Takehiro Izumo and Chih-Yen Tu and Wen-Chien Cheng and Matthew Evison and Tang-Feng Lv and Yong Song and written on behalf of the AME Lung Cancer Collaborative Group},
title = {Comparison between endobronchial ultrasound-guided transbronchial biopsy and CT-guided transthoracic lung biopsy for the diagnosis of peripheral lung cancer: a systematic review and meta-analysis},
journal = {Translational Lung Cancer Research},
volume = {6},
number = {1},
year = {2017},
keywords = {},
abstract = {Background: With the release of the National Lung Screening Trial results, the detection of peripheral pulmonary lesions (PPLs) is likely to increase. Computed tomography (CT)-guided percutaneous transthoracic needle biopsy (PTNB) and radial probe endobronchial ultrasound (r-EBUS)-guided transbronchial lung biopsy (TBLB) are recommended for tissue diagnosis of PPLs.
Methods: A systematic review of published literature evaluating the accuracy of r-EBUS-TBLB and CT-PTNB for the diagnosis of PPLs was performed to determine point sensitivity and specificity, and to construct a summary receiver-operating characteristic curve.
Results: This review included 31 publications dealing with EBUS-TBLB and 14 publications dealing with CT-PTNB for the diagnosis of PPLs. EBUS-TBLB had point sensitivity of 0.69 (95% CI: 0.67–0.71) for the diagnosis of peripheral lung cancer (PLC), which was lower than the sensitivity of CT-PTNB (0.94, 95% CI: 0.94–0.95). However, the complication rates observed with EBUS-TBLB were lower than those reported for CT-PTNB.
Conclusions: This meta-analysis showed that EBUS-TBLB is a safe and relatively accurate tool in the investigation of PLC. Although the yield remains lower than that of CT-PTNB, the procedural risks are lower.},
issn = {2226-4477}, url = {https://tlcr.amegroups.org/article/view/11855}
}