TY  - JOUR
AU  - Tsuchihara, Katsuya
PY  - 2013
TI  - RET-targeting molecular stratified non-small-cell lung cancers
JF  - Translational Lung Cancer Research; Vol 2, No 6 (December 31, 2013): Translational Lung Cancer Research
Y2  - 2013
KW  - 
N2  - Recent advances in lung cancer genomics have successfully characterized therapeutic targets of lung cancer. RET fusion gene products are among the newest target molecules for lung adenocarcinoma. Preclinical findings and preliminary reports regarding potential tumor control by RET-targeting multikinase inhibitors encourage further clinical trials. The infrequent prevalence of RET fusion gene-positive cases may be a major obstacle hindering the development of RET-targeted therapy. Thus, it is necessary to recruit appropriate participants for trials to develop an efficient RET fusion gene detection system to achieve targeted therapy for lung adenocarcinomas stratified by this molecular target.
UR  - https://tlcr.amegroups.org/article/view/1765