%0 Journal Article %T Development of biomarkers for real precision medicine %A Shibata, Masahiro %A Hoque, Mohammad Obaidul %J Translational Lung Cancer Research %D 2018 %B 2018 %9 %! Development of biomarkers for real precision medicine %K %X Most cancers are genetically heterogeneous diseases, and many genes or gene products have altered their expressions or activities in cancer cells due to a variety of genetic and epigenetic mechanisms in DNA. Copy number aberrations (CNAs), common genomic events during carcinogenesis, are known to affect a large fraction of genome and extensively studied for last several decades. %U https://tlcr.amegroups.org/article/view/23559 %P S228-S231 %@ 2226-4477