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STAT3 cyclic oligonucleotide decoy—a new therapeutic avenue for NSCLC?

   
@article{TLCR24457,
	author = {Lennard Y. W. Lee and Summaya Mohammad and Thomas Starkey and Siow-Ming Lee},
	title = {STAT3 cyclic oligonucleotide decoy—a new therapeutic avenue for NSCLC?},
	journal = {Translational Lung Cancer Research},
	volume = {7},
	number = {Suppl 4},
	year = {2018},
	keywords = {},
	abstract = {Lung cancer is still the main cause of cancer-related death and accounts for nearly 1.8 million deaths worldwide every year (1,2). About 85–90% of patients with lung cancer have non-small cell lung cancer (NSCLC) with most presenting with advanced metastatic disease. Despite the introduction of immune check-point inhibitors (IO) and newer generation of more effective EGFR TKIs and ALK inhibitors recently, there is still an unmet clinical need for improved treatment options for both wild-type and oncogenic-addicted NSCLC as most of these treated patients still develop disease resistance. Novel treatment strategies including identifying new treatment targets are still needed to improve outcome.},
	issn = {2226-4477},	url = {https://tlcr.amegroups.org/article/view/24457}
}