@article{TLCR34623,
author = {Keyi Jia and Yayi He and Rafal Dziadziuszko and Sha Zhao and Xiaoshen Zhang and Juan Deng and Hao Wang and Fred R. Hirsch and Caicun Zhou and Hui Yu and Liping Zhang},
title = {T cell immunoglobulin and mucin-domain containing-3 in non-small cell lung cancer},
journal = {Translational Lung Cancer Research},
volume = {8},
number = {6},
year = {2020},
keywords = {},
abstract = {Background: Immunotherapy has shown promising effect for non-small cell lung cancer (NSCLC) patients. Yet the biomarkers for predicting immunotherapy efficiency are still lacking.
Methods: We tested 139 surgical resected NSCLC primary tumor samples from Medical University of Gdansk, Poland, for T cell immunoglobulin and mucin-domain containing-3 (TIM-3) level by immunohistochemistry (IHC), analyzed the expression of TIM-3 protein on NSCLC tumor cells and tumor infiltrating lymphocytes (TILs).
Results: TIM-3 on TILs was correlated with programmed cell death protein-1 (PD-1) on TILs (correlation coefficient =0.346, P},
issn = {2226-4477}, url = {https://tlcr.amegroups.org/article/view/34623}
}