@article{TLCR526,
author = {Bin-Chi Liao and James Chih-Hsin Yang},
title = {Front-line erlotinib in unselected patient with advanced NSCLC followed by standard chemotherapy with gemcitabine and cisplatin - TORCH study},
journal = {Translational Lung Cancer Research},
volume = {1},
number = {3},
year = {2012},
keywords = {},
abstract = {Result from BR. 21 study demonstrated that in unselected patients with advanced non-small cell lung cancer (NSCLC) pretreated with standard first-line or second-line chemotherapy, subsequent erlotinib treatment prolonged overall survival (OS) as compared to placebo (1). Erlotinib was evaluated as front-line therapy for unselected patients with advanced NSCLC. In a phase II study of erlotinib in NSCLC patients, Giaccone et al. (2) demonstrated a tumor response rate of 22.7% and a median overall survival of 391 days. In elderly patients treated with frontline erlotinib, the response rate was 10%, and median timeto- progression (TTP) and overall survival (OS) were 3.5 and 10.9 months respectively (3).},
issn = {2226-4477}, url = {https://tlcr.amegroups.org/article/view/526}
}