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Case Report

Surgical Conversion After Anaplastic Lymphoma Kinase-Tyrosine Kinase Inhibitors Therapy in N3 Stage ALK-Positive NSCLC: A Report of Three Cases

Beike Xiao, Hao Guo, Jiatao Zhang, Xue-ning Yang

Published online: 30 September 2026

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Original Article

Quantitative CT definition of solid components in pulmonary ground-glass nodules: a pixel-level annotation-based development and internal validation study

Yuhao Chen, Nan Chen, Yuhuan Ye, Han Zhang, Wanting Xia, Kunhao Wu, Nanzhi Luo, Zhenyi Niu, Le Yi, Qiang Pu, Xiuyuan Xu, Lunxu Liu

Published online: 29 September 2026

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Original Article

Real-World Outcomes of Neoadjuvant Targeted Therapy in Resectable Epidermal Growth Factor Receptor Mutation-Positive Non-Small-Cell Lung Cancer: A Retrospective Study

Jia Li, Yinguang Zhang, Jie Gao, Hui Deng, Zhiming Luo, Xidong Ma, Mei Xie, Xinying Xue

Published online: 29 September 2026

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Case Report

Diagnostic challenge of delayed immune-related hepatitis during zongertinib treatment after nivolumab plus ipilimumab in a 52-year-old man with HER2-mutant non-small cell lung cancer: a case report

Tomohiro Oba, Shunya Shiohira, Yoko Machida, Daisuke Nakatani, Keiichi Akasaka, Masako Amano, Hidekazu Matsushima

Published online: 29 September 2026

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Original Article

Perioperative treatment for resectable non-small cell lung cancer harboring EGFR exon 20 insertion mutations: a narrative review from advanced-stage evidence to whole-course precision management

Zhuoran Li, Yichao Han, Wenzhao Zhong, Hecheng Li

Published online: 29 September 2026

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Original Article

Machine-learning-assisted multi-omics profiling identifies CALB1 as a subtype-associated regulator of PI3K/AKT signaling and malignant progression in non-small cell lung cancer

Feng Mao, Ning Wang, Yuming Wang, Ziang Wang, Hui Zhang, Qingquan Luo

Published online: 29 September 2026

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Original Article

Surgical de-escalation strategies for non-small cell lung cancer following neoadjuvant chemoimmunotherapy: a propensity score-matched analysis

Yulong Wang, Bengang Hui, Xin Wang, Guihu Lin, Xun Wang, Xiao Li

Published online: 29 September 2026

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Original Article

A cross-sectional benchmark of seven large language models for national comprehensive cancer network guideline adherence in non-small cell lung cancer management

Zewen Sun, Tian Guan, Jiayi Geng, Junwei Liu, Dexin Su, Tao Sun, Gangzeng Jin, Heng Zhao, Shaodong Wang, Geyun Chang, Guihu Lin, Changtai Zhao, Kexin Feng, Hongchengcheng Chen, Jiaming Deng, Ruzhen Li, Jun Wang, Peihao Li, Liqi Liu, Yun Li, Fan Yang, Jun Wang, Xin Wang, Ailing Yu, Yuan Xia, Dongjie Tao, Hualei Zhou, Chunxiao Guo, Peng Wei, Jian Wang, Jinjie Gu, Yanyun Wang, Jing Zhao, Shuai Zhen, Kezhong Chen, Ping Wang, Xiuyuan Chen

Published online: 29 September 2026

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Original Article

Pathological high-risk feature count and survival outcomes in patients with stage I invasive lung adenocarcinoma (≤3 cm): a retrospective cohort study

Jie Cao, Nan Chen, Yin Ku, Zhiyu Peng, Zhaokang Huang, Zetao Liu, Xizhou Liao, Xiaorong Zong, Peidi Li, Chenglin Guo, Jiandong Mei, Lunxu Liu

Published online: 29 September 2026

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Original Article

Development and internal validation of a multimodal deep learning model integrating imaging, clinical and pathological features to predict false-negatives in non-specific benign lung biopsies: a dual-center study

Jing Yuan, Wei Li, Chunhua Liu, Luxing He, Qian Yang, Ruili Mao, Xuequan Huang, Weiguo Zhang, Jingjing Liu

Published online: 29 September 2026

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Original Article

Prognostic value of a three-dimensional spatial classification system for clinical T1a-bN0 non-small cell lung cancer in the superior segment

Yihan Yang, Angat Naresh Chadha, Yingchao Gu, Ruizhi Gong, Qianrui Ren, Xinfeng Xu, Wei Wen, Zhibo Wang, Quan Zhu

Published online: 29 September 2026

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Original Article

Genomic characteristics, survival and prognostic analysis of advanced non-small cell lung cancer with Kirsten rat sarcoma mutations and brain metastases

Yi Chen, Xiheng Yu, Mengqi Bao, Xiaoqing Yu, Yuwei Li, Jing Sun, Linjing Zhou, Yunfeng Tong, Yun Fan

Published online: 29 September 2026

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Original Article

Perioperative and early oncologic outcomes of complex segmentectomy via uniportal video-assisted thoracic surgery for primary lung cancer

Takuya Watanabe, Eriko Suzuki, Naoko Yoshii, Takuya Kohama, Kensuke Iguchi, Masayuki Tanahashi, Katsuhiro Okuda

Published online: 29 September 2026

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Original Article

Segmental distribution of hepatic steatosis on opportunistic low-dose CT: a Couinaud-based analysis

Ingrid Galvis, Jonathan Alis, Mary Salvatore

Published online: 29 September 2026

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Case Report

Lung adenocarcinoma with rapid progression and fatal outcome through spread through air spaces: an autopsy case report

Jun Arinami, Yu Saida, Shintaro Yoneyama, Satoshi Watanabe, Tomoki Sekiya, Ryo Suzuki, Naohiro Yanagimura, Miyuki Sato, Koichiro Nozaki, Tomohiro Tanaka, Saori Takashima, Yusuke Tani, Kazuyuki Ozaki, Takeshi Kashimura, Takayuki Inomata, Toshiaki Kikuchi

Published online: 29 September 2026

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Original Article

Single cell imaging mass spectrometry spatial immune profiling of brain metastasis from non-small-cell lung cancer patients treated with immune checkpoint inhibitors

Dan Zhao, Haiqing Li, Isa Mambetsariev, Tamara Mirzapoiazova, Jeremy Fricke, Javier Arias-Romero, Leonidas Arvanitis, Massimo D’Apuzzo, Bradford Tan, Michelle Afkhami, Brian Armstrong, Mike Y. Chen, Behnam Badie, Bihong Beth Chen, Arya Amini, Ravi Salgia

Published online: 29 September 2026

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Original Article

Explainable machine learning for predicting grade ≥3 treatment-related adverse events in resectable non-small cell lung cancer receiving neoadjuvant chemoimmunotherapy: predominant contribution of hematologic toxicity

Fei-Hang Zhi, Yunzeng Zhang, Tengfei Ge, Lei Yang, Yichen Dong, Jialiang Wen, Haojie Si, Jingyu Chen, Yuzhou Wang, Delun Yang, Yicheng Wang, Minglei Yang, Huikang Xie, Junqi Wu, Long Xu, Deping Zhao, Chang Chen

Published online: 29 September 2026

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Original Article

Functional decline at progression after durvalumab in stage III non-small cell lung cancer: prognostic impact and treatment patterns in a multicenter retrospective cohort study

Maja Lisik-Habib, Krzysztof Smółka, Rafał Stando, Grzegorz Chmielewski, Mateusz Bilski, Katarzyna Galwas, Damian Tworek, Mirosława Puskulluoglu, Agnieszka Roman, Małgorzata Terlecka-Maciejewska, Jacek Fijuth, Łukasz Kuncman

Published online: 28 September 2026

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Review Article

Antibody-Drug Conjugates in the Perioperative Treatment of Resectable Non-Small Cell Lung Cancer: A Narrative Review of Research Advances and Prospects

Ying Xiong, Lu Sun, Yi Peng

Published online: 28 September 2026

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Original Article

Emphysema reprograms neutrophils toward a tumor-promoting phenotype in lung cancer

Mohamad Qaisi, Merav E. Shaul, Nuha Alsharif, Naomi Kaisar-Iluz, Sojod Mahroum, Osnath Bouhanna, Yael Volman, Zvi G. Fridlender

Published online: 28 September 2026

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Original Article

Bronchoalveolar lavage fluid cfDNA liquid biopsy-guided neoadjuvant lazertinib in resectable EGFR-mutant NSCLC: a prospective phase II study

In Ae Kim, Heejoung Kim, Jae Young Hur, Wan Seop Kim, Young Whan Kim, Song Am Lee, Jae Joon Hwang, Kye Young Lee

Published online: 28 September 2026

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Original Article

Efficacy and safety of stereotactic body radiotherapy combined with immune checkpoint inhibitors for non-small cell lung cancer: a systematic review and reconstructed individual patient data meta-analysis

Pengfei Ji, Zhihui Zhao, Xinpu Tang, Zhangyi Dai, Xingqi Mi, Yikai Xing, Yafei Xie, Wei Liao, Xiaolong Zhang, Qiang Pu

Published online: 28 September 2026

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Original Article

An integrated baseline CT model for predicting growth heterogeneity in solid lung cancer with transcriptomic annotation

Jiaqi Chen, Linlin Qi, Jianing Liu, Fenglan Li, Shulei Cui, Sainan Cheng, Weixiong Tan, Jianwei Wang

Published online: 24 September 2026

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Original Article

Association between adjuvant EGFR-TKI therapy and survival outcomes in completely resected stage I invasive lung adenocarcinoma (≤3 cm) with sensitizing EGFR mutations and pathological high-risk features

Jie Cao, Zhaokang Huang, Fang Qiu, Nan Chen, Zhiyu Peng, Zetao Liu, Xizhou Liao, Xiaorong Zong, Peidi Li, Chenglin Guo, Jiandong Mei, Lunxu Liu

Published online: 24 September 2026

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