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Original Article

Utility of atezolizumab plus bevacizumab, carboplatin, and paclitaxel combination for the treatment of advanced non-squamous non-small cell lung cancer patients with malignant pleural effusion
Kakeru Hisakane, Kenichiro Atsumi, Masahiro Seike, Takashi Hirose
TFAP2A-activated ITGB4 promotes lung adenocarcinoma progression and inhibits CD4+/CD8+ T-cell infiltrations by targeting NF-κB signaling pathway
Cheng Pan, Zhibo Wang, Qi Wang, Hongshun Wang, Xiaheng Deng, Liang Chen, Zhihua Li
IL-1 receptor-associated kinase 3 (IRAK3) in lung adenocarcinoma predicts prognosis and immunotherapy resistance: involvement of multiple inflammation-related pathways
Yang Zhou, Wei Rao, Zhao Li, Wei Guo, Fei Shao, Zhen Zhang, Hao Zhang, Tiejun Liu, Zitong Li, Fengwei Tan, Qi Xue, Shugeng Gao, Jie He
Ten-year survival outcomes of video-assisted thoracic surgery vs. open major lung resection for stage I–III non-small cell lung cancer: a large cohort study in China
Yiming Li, Jiandong Mei, Zhenyu Yang, Chenglin Guo, Chengwu Liu, Hu Liao, Lin Ma, Feng Lin, Yidan Lin, Yong Yuan, Yunke Zhu, Yuyang Xu, Zheng Liu, Kaidi Li, Yang Hu, Yun Wang, Nan Chen, Zhu Wu, Chuan Li, Liang Xia, Jian Zhou, Xiaolong Zhang, Cheng Shen, Qiang Pu, Lunxu Liu
Diagnostic efficacy of cryobiopsy for peripheral pulmonary lesions with ground-glass opacity: a propensity score-matched analysis
Hideaki Furuse, Yuji Matsumoto, Toshiyuki Nakai, Midori Tanaka, Kanako Nishimatsu, Keigo Uchimura, Tatsuya Imabayashi, Takaaki Tsuchida
Incidence, prevalence, and survival of lung cancer in the United Kingdom from 2000–2021: a population-based cohort study
George Corby, Nicola L. Barclay, Eng Hooi Tan, Edward Burn, Antonella Delmestri, Talita Duarte-Salles, Asieh Golozar, Wai Yi Man, Ilona Tietzova, Daniel Prieto-Alhambra, Danielle Newby
Trends in the prescription of immune checkpoint inhibitors for non-small cell lung cancer in the Netherlands from 2016 to 2020, a national cancer registry analysis
Erick Suazo-Zepeda, Willemijn J. Maas, Petra C. Vinke, T. Jeroen N. Hiltermann, Mieke J. Aarts, Geertruida Hendrika de Bock, Marjolein A. Heuvelmans
Efficacy of first-line immune checkpoint inhibitors in pulmonary sarcomatoid carcinoma
Gary Birsen, Valérie Gounant, Nicolas Girard, Jacques Cadranel, Isabelle Monnet, Christine Raynaud-Donzel, Elizabeth Fabre, Etienne Giroux Leprieur, Karen Leroy, Diane Damotte, Marco Alifano, Jennifer Arrondeau, Isabelle Cremer, Jeanne Chapron, Marie Wislez
Molecular subtypes and prognostic factors of lung large cell neuroendocrine carcinoma
Tingting Liu, Xueyuan Chen, Silang Mo, Ting Zhou, Wenjuan Ma, Gang Chen, Xiang Chen, Mengting Shi, Yuwen Yang, Yan Huang, Hongyun Zhao, Wenfeng Fang, Yunpeng Yang, Jing Li, Li Zhang, Yuanyuan Zhao
Lymph nodes rather than pleural metabolic activity in 18F-FDG PET/CT correlates with malignant pleural effusion recurrence in advanced non-small cell lung cancer
Yuxin Jiang, Tao Liu, Ke Xu, Qinpei Cheng, Wanjun Lu, Jingyuan Xie, Mo Chen, Yu Li, Yanjun Du, Shuo Liang, Yong Song, Jiang Wu, Tangfeng Lv, Ping Zhan
Establishment of a survival predictive model for patients with two synchronous multiple primary lung cancers: a multicenter cohort analysis
Ying Ji, Qing Zhao, Yi Liu, Bin Qiu, Guangyu Bai, Siyuan Ai, Wei Feng, Ligong Yuan, Xin Wang, Lulu Rong, Hua Fu, Huihui Xie, Linlin Qi, Ye Tao, Longyu Jin, Jing Zhou, Bin Hu, Shugeng Gao
Establishing a predictive model for tumor mutation burden status based on 18F-FDG PET/CT and clinical features of non-small cell lung cancer patients
Zheng Chen, Xueping Chen, Linjun Ju, Yue Li, Wenbo Li, Hua Pang
Serum tumor markers and outcomes in lung cancer patients with brain metastases: a retrospective longitudinal cohort study
Yingtong Liu, Shuang Dai, Zheran Liu, Ling He, Lili Zhu, Zijian Qin, Haohan Fan, Fang Fang, Yuping Xie, Xingchen Peng
Tremelimumab and durvalumab with chemotherapy in first-line treatment for metastatic non-small cell lung cancer: a US-based cost-effectiveness analysis
Ziying Zhao, Xiaohui Zeng, Zhen Zhou, Qiao Liu
TRIM27 revealing by tumor educated platelet RNA-sequencing, as a potential biomarker for malignant ground-glass opacities diagnosis mediates glycolysis of non-small cell lung cancer cells partially through HOXM1
Yan Hu, Chao Zeng, Jina Li, Siying Ren, Mengqi Shao, Weixuan Lei, Junqi Yi, Wei Han, Jieming Cao, Jian Zou, Quanming Fei, Zeyu Cheng, Wenliang Liu
Prognostic value of circulating proteins at diagnosis among patients with lung cancer: a comprehensive analysis by smoking status
Xiaoshuang Feng, Hilary A. Robbins, Anush Mukeriya, Lenka Foretova, Ivana Holcatova, Vladimir Janout, Jolanta Lissowska, Miodrag Ognjanovic, Beata Swiatkowska, David Zaridze, Paul Brennan, Mattias Johansson, Mahdi Sheikh
Establishment of lung cancer cell lines and tumorigenesis in mice from malignant pleural effusion in patients with lung cancer
Nobuhiro Kanaji, Masanao Yokohira, Takuya Inoue, Naoki Watanabe, Hitoshi Mizoguchi, Yuta Komori, Kosuke Kawada, Norimitsu Kadowaki
Stem-like exhausted CD8 T cells in pleural effusions predict improved survival in non-small cell lung cancer (NSCLC) and mesothelioma
Linda Ye, Heeju Ryu, David Granadier, Long T. Nguyen, Yannick Simoni, Ian Dick, Tina Firth, Ebony Rouse, Peter Chiang, Y. C. Gary Lee, Bruce W. Robinson, Jenette Creaney, Evan W. Newell, Alec J. Redwood
A multi-level investigation of the genetic relationship between gastroesophageal reflux disease and lung cancer
Dongsheng Wu, Jian Zhou, Lujia Song, Quan Zheng, Tengyong Wang, Zhizhen Ren, Yuchen Huang, Shuqiao Liu, Lunxu Liu
Association between fruit intake and non-small cell lung cancer: a Mendelian randomization study
Chongde Pan, Ying Du, Yu Jiang, Yuechun Lin, Yulin Zhao, Huiwen Yu, Hengrui Liang, Wanzhe Liao, Xin Xu, Ying Huang
Tumor immune microenvironment analysis of non-small cell lung cancer development through multiplex immunofluorescence
Jiaping Zhao, Yu Lu, Zhaofeng Wang, Haiying Wang, Ding Zhang, Jinping Cai, Bei Zhang, Junling Zhang, Mengli Huang, Andreas Pircher, Krishna H. Patel, Honggang Ke, Yong Song
Effect of laterality on the postoperative survival of non-small cell lung cancer patients undergoing pneumonectomy
Zi-Ming Wang, Liang Guo, Yang Yang, Bo Tao, Wen-Qiang Zhang, Diego Gonzalez-Rivas, Jens-C Rueckert, Chee Yik Er, Calvin S. H. Ng, Moshe Lapidot, Gaetano Rocco, Mahmoud Ismail, Chen-Lu Yang, De-Ping Zhao
Histopathologic pattern and molecular risk stratification are associated with prognosis in patients with stage IB lung adenocarcinoma
Weiran Liu, Chen Chen, Qiang Zhang, Jiping Xie, Xinyi Wu, Zhenfa Zhang, Lin Shao, Haiwei Du, Songan Chen, Hirokazu Iso, Kakeru Hisakane, Dongsheng Yue, Bin Zhang
EGFR mutations in patients with lung adenocarcinoma and malignant pleural effusion: a propensity score-matched analysis of a single-center database
Qiwei Yang, Ziyi Wang, Qiang Fu, Xiaohai Hu, Liang Chen, Weiyang Chen, Ling Lv, Zhenghua Liu, Wanfu Men, Danni Li, Wenya Li

Images in Clinical Medicine

Squamous-cell carcinoma of the recipient’s explanted lung
Yuan Zeng, Guilin Peng, Chao Yang, Mengyang Liu, Weixue Cui, Jinzhu Mao, Jianxing He, Xin Xu
Review Articles 
Irreversible EGFR-TKIs: dreaming perfection
Lorenza Landi, Federico Cappuzzo
Published online: 14 January 2013
Review Article 
Non-small cell lung cancer: current treatment and future advances
Cecilia Zappa, Shaker A. Mousa
Published online: 30 June 2016
Review Article 
Pulmonary ground-glass opacity: computed tomography features, histopathology and molecular pathology
Jian-Wei Gao, Stefania Rizzo, Li-Hong Ma, Xiang-Yu Qiu, Arne Warth, Nobuhiko Seki, Mizue Hasegawa, Jia-Wei Zou, Qian Li, Marco Femia, Tang-Feng Lv, Yong Song, written on behalf of the AME Lung Cancer Collaborative Group
Published online: 28 February 2017
Review Article 
Recurrence after surgery in patients with NSCLC
Hidetaka Uramoto, Fumihiro Tanaka
Published online: 28 August 2014
Review Article 
The past, present and future of immunotherapy against tumor
Tao Jiang, Caicun Zhou
Published online: 24 June 2015
Review Article 
Treatment of uncommon EGFR mutations in non-small cell lung cancer: new evidence and treatment
Tianli Zhang, Bing Wan, Yuan Zhao, Chuling Li, Hongbing Liu, Tangfeng Lv, Ping Zhan, Yong Song
Published online: 30 June 2019
Review Article 
Ground-glass nodules of the lung in never-smokers and smokers: clinical and genetic insights
Yoshihisa Kobayashi, Chiara Ambrogio, Tetsuya Mitsudomi
Published online: 28 August 2018
Review Articles 
KRAS mutant NSCLC, a new opportunity for the synthetic lethality therapeutic approach
Javier de Castro Carpeño, Cristóbal Belda-Iniesta
Published online: 03 April 2013
Review Article 
Molecular testing strategies in non-small cell lung cancer: optimizing the diagnostic journey
Jeffrey P. Gregg, Tianhong Li, Ken Y. Yoneda
Published online: 30 June 2019
Review Article on Update on Pathology and Predictive Biomarkers of Lung Cancer 
Biology of invasive mucinous adenocarcinoma of the lung
Yoon Jin Cha, Hyo Sup Shim
Published online: 11 October 2017
Review Article 
The epidemiology of lung cancer
Patricia M. de Groot, Carol C. Wu, Brett W. Carter, Reginald F. Munden
Published online: 14 June 2018
Review Articles 
New TNM classification: achievements and hurdles
Peter Goldstraw
Published online: 17 August 2013
Consensus 
Tubeless video-assisted thoracic surgery for pulmonary ground-glass nodules: expert consensus and protocol (Guangzhou)
Jianxing He, Hengrui Liang, Wei Wang, Andrey Akopov, Alberto Aiolfi, Keng-Leong Ang, Luca Bertolaccini, Kaican Cai, Qingdong Cao, Baojun Chen, Chang Chen, Chun Chen, Donglai Chen, Fengxia Chen, Jun Chen, Lei Chen, Mingwu Chen, Yongbing Chen, Zhuxing Chen, Chao Cheng, Dong Cui, Fei Cui, Tianyang Dai, Qinglong Dong, Paolo A. Ferrari, Raja M. Flores, Junke Fu, Soichiro Funaki, Marios E. Froudarakis, Xiangfeng Gan, Mingfei Geng, Jialong Guo, Qiang Guo, Yongtao Han, Jintao He, Kaiming He, Kyoji Hirai, Jian Hu, Shuqiao Hu, Jian Huang, Jun Huang, Wenfa Jiang, Kyung Soo Kim, Gabor Kiss, Fanyi Kong, Lan Lan, Xuefeng Leng, Bin Li, Gaofeng Li, Hecheng Li, Hefei Li, Heng Li, Jiwei Li, Xiaoqiang Li, Shuben Li, Yinfen Li, Zhuoyi Li, Yi Liang, Lixia Liang, Wenhua Liang, Yongde Liao, Wanli Lin, Xu Lin, Hongxu Liu, Hui Liu, Jixian Liu, Jun Liu, Xiang Liu, Zihao Liu, Xingzhao Lu, Qingquan Luo, Naiquan Mao, Qi Pan, Dazhi Pang, Jun Peng, Jun Peng, Eugenio Pompeo, Rulin Qian, Kun Qiao, Bassam Redwan, Zi Sang, Wenlong Shao, Jianfei Shen, Weiyu Shen, Sook-Whan Sung, Wenfang Tang, Tianhu Wang, Guangsuo Wang, Haitao Wang, Huien Wang, Jiyong Wang, Wen Wang, Yongyong Wang, Zhenyuan Wang, Li Wei, Wei Wei, Hao Wu, Jie Wu, Zhaohua Xia, Chenyang Xu, Enwu Xu, Hai Xu, Ning Xu, Quan Xu, Rongyu Xu, Shun Xu, Chaokun Yang, Hanyu Yang, Shengli Yang, Jun Yi, Guangjian Zhang, Hao Zhang, Jia Zhang, Man Zhang, Xiao Zhang, Yajie Zhang, Zhe Zhang, Zhifeng Zhang, Honglin Zhao, Jian Zhao, Xiaodong Zhao, Jianping Zhou, Yanran Zhou, Chengchu Zhu, Shaojin Zhu, Xinhai Zhu, Jian Cui, Yubo Yan, Ke-Neng Chen
Published online: 28 August 2021
Review Article 
Lung cancer screening: nodule identification and characterization
Ioannis Vlahos, Konstantinos Stefanidis, Sarah Sheard, Arjun Nair, Charles Sayer, Joanne Moser
Published online: 14 June 2018
Review Article 
Beyond ALK-RET, ROS1 and other oncogene fusions in lung cancer
Takashi Kohno, Takashi Nakaoku, Koji Tsuta, Katsuya Tsuchihara, Shingo Matsumoto, Kiyotaka Yoh, Koichi Goto
Published online: 19 April 2015
Review Articles 
Angiogenesis in cancer: anti-VEGF escape mechanisms
Gerald W. Prager, Marina Poettler, Matthias Unseld, Christoph C. Zielinski
Published online: 18 February 2012

Original Article

Prognostic value of Twist in lung cancer: systematic review and meta-analysis
Junli Zeng, Ping Zhan, Guannan Wu, Wen Yang, Wenjun Liang, Tangfeng Lv, Yong Song
BRAF mutations in non-small cell lung cancer
Peter P. Luk, Bing Yu, Chiu Chin Ng, Belinda Mercorella, Christina Selinger, Trina Lum, Steven Kao, Sandra A. O’Toole, Wendy A. Cooper
The suitability of small biopsy and cytology specimens for EGFR and other mutation testing in non-small cell lung cancer
Shu Wang, Bing Yu, Chiu Chin Ng, Belinda Mercorella, Christina I. Selinger, Sandra A. O’Toole, Wendy A. Cooper
Itraconazole can inhibit malignant pleural effusion by suppressing lymphangiogenesis in mice
Yunfen Wang, Yanwen Yao, Hongbin Liu, Xingqun Ma, Tangfeng Lv, Dongmei Yuan, Xinwu Xiao, Jie Yin, Yong Song
Ratio of maximum standardized uptake value to primary tumor size is a prognostic factor in patients with advanced non-small cell lung cancer
Fangfang Chen, Yanwen Yao, Chunyan Ma, Xingqun Ma, Zhaofeng Wang, Tangfeng Lv, Xinwu Xiao, Jie Yin, Yong Song
Advanced proton beam dosimetry part II: Monte Carlo vs. pencil beam-based planning for lung cancer
Dominic Maes, Jatinder Saini, Jing Zeng, Ramesh Rengan, Tony Wong, Stephen R. Bowen
The cytokinesis-blocked micronucleus assay as a novel biomarker for selection of lung cancer screening participants
Randa A. El-Zein, Carol J. Etzel, Reginald F. Munden
The use of TCP based EUD to rank and compare lung radiotherapy plans: in-silico study to evaluate the correlation between TCP with physical quality indices
Abdulhamid Chaikh, Jacques Balosso

Review Article

Beyond ALK-RET, ROS1 and other oncogene fusions in lung cancer
Takashi Kohno, Takashi Nakaoku, Koji Tsuta, Katsuya Tsuchihara, Shingo Matsumoto, Kiyotaka Yoh, Koichi Goto
Overview of clinicopathologic features of ALK-rearranged lung adenocarcinoma and current diagnostic testing for ALK rearrangement
Hyojin Kim, Jin-Haeng Chung
Neoadjuvant and adjuvant epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy for lung cancer
Haoran Zhai, Wenzhao Zhong, Xuening Yang, Yi-Long Wu
Known and putative mechanisms of resistance to EGFR targeted therapies in NSCLC patients with EGFR mutations—a review
Erin L. Stewart, Samuel Zhixing Tan, Geoffrey Liu, Ming-Sound Tsao
Clinical trials for lung cancer in China
Fei-Yu Niu, Wen-Zhao Zhong, Qing Zhou, Yi-Long Wu
Recurrence after surgery in patients with NSCLC
Hidetaka Uramoto, Fumihiro Tanaka
Prognostic markers in lung cancer: is it ready for prime time?
Chang-Qi Zhu, Ming-Sound Tsao
Potential biomarkers for lung cancer screening
Gabriella Sozzi, Mattia Boeri
Particle therapy in non-small cell lung cancer
Zhongxing Liao, Charles B. Simone II
Computer Aided Nodule Analysis and Risk Yield (CANARY) characterization of adenocarcinoma: radiologic biopsy, risk stratification and future directions
Ryan Clay, Srinivasan Rajagopalan, Ronald Karwoski, Fabien Maldonado, Tobias Peikert, Brian Bartholmai
Immunotherapy and radiation therapy for operable early stage and locally advanced non-small cell lung cancer
Neil K. Taunk, Andreas Rimner, Melissa Culligan, Joseph S. Friedberg, Julie Brahmer, Jamie Chaft
Combining immunotherapy and radiation therapy for small cell lung cancer and thymic tumors
Suchit H. Patel, Andreas Rimner, Roger B. Cohen
Intraoperative near-infrared imaging of mesothelioma
Gregory Thomas Kennedy, Andrew Newton, Jarrod Predina, Sunil Singhal
BAP1, a tumor suppressor gene driving malignant mesothelioma
Mitchell Cheung, Joseph R. Testa
Uncovering the immune tumor microenvironment in non-small cell lung cancer to understand response rates to checkpoint blockade and radiation
Jonathan E. Schoenhals, Steven N. Seyedin, Clark Anderson, Eric D. Brooks, Yun R. Li, Ahmed I. Younes, Sharareh Niknam, Ailin Li, Hampartsoum B. Barsoumian, Maria Angelica Cortez, James W. Welsh
Diagnostic and prognostic biomarkers for malignant mesothelioma: an update
Zhongjian Chen, Giovanni Gaudino, Harvey I. Pass, Michele Carbone, Haining Yang
Immunotherapy for malignant pleural mesothelioma: current status and future directions
Jordan Dozier, Hua Zheng, Prasad S. Adusumilli
Biology and clinical significance of circulating tumor cell subpopulations in lung cancer
Linda O’Flaherty, Harriet Wikman, Klaus Pantel
Routine clinical use of circulating tumor cells for diagnosis of mutations and chromosomal rearrangements in non-small cell lung cancer—ready for prime-time?
Emma Pailler, Vincent Faugeroux, Marianne Oulhen, Cyril Catelain, Françoise Farace
Challenges and unanswered questions for the next decade of circulating tumour cell research in lung cancer
Sumitra Mohan, Francesca Chemi, Ged Brady
Biophysical technologies for understanding circulating tumor cell biology and metastasis
Derrick W. Su, Jorge Nieva
Clinical utility of circulating tumor cells in patients with non-small-cell lung cancer
Marianna Gallo, Antonella De Luca, Monica Rosaria Maiello, Amelia D’Alessio, Claudia Esposito, Nicoletta Chicchinelli, Laura Forgione, Maria Carmela Piccirillo, Gaetano Rocco, Alessandro Morabito, Gerardo Botti, Nicola Normanno
Integrating immunotherapy into chemoradiation regimens for medically inoperable locally advanced non-small cell lung cancer
Salma K. Jabbour, Abigail T. Berman, Charles B. Simone II

Systematic Review and Meta-analysis

Association of the metformin with the risk of lung cancer: a meta-analysis
Li Wang, Yong Song, Guan-Nan Wu, Dong-Mei Yuan

Editorials

Dulanermin in cancer therapy: Still much to do
Cristina Quintavalle, Gerolama Condorelli

Review Articles

EGFR molecular testing in African-American non-small cell lung cancer patients - a review of discrepant data
Bradley T. Clifford, Pingfu Fu, Nathan A. Pennell, Balazs Halmos, Rom S. Leidner
Copy number gains of FGFR1 and 3q chromosome in squamous cell carcinoma of the lung
Pedro Mendez, Jose Luis Ramirez
Role of HGF/MET axis in resistance of lung cancer to contemporary management
Kanwal Pratap Singh Raghav, Ana Maria Gonzalez-Angulo, George R. Blumenschein Jr
Circulating soluble intercellular adhesion Molecule-1 in lung cancer: a systematic review
Xiaoling Gu, Chunyan Ma, Dongmei Yuan, Yong Song

Onartuzumab plus erlotinib

Targeting MET in NSCLC: looking for a needle in a haystack
Lorenza Landi, Federico Cappuzzo

Review Article on Update on Pathology and Predictive Biomarkers of Lung Cancer

Biology of invasive mucinous adenocarcinoma of the lung
Yoon Jin Cha, Hyo Sup Shim
Immunohistochemistry for predictive biomarkers in non-small cell lung cancer
Mari Mino- Kenudson

Below are the latest Translational Lung Cancer Research articles published online ahead of print publication.