Vol 3, No 6 (December 19, 2014): Translational Lung Cancer Research (Personalized Therapy in Lung Cancer)

Preface

Special issue on personalized therapy in lung cancer
Na Zhang, Wen-Zhao Zhong, Yi-Long Wu
Translational Lung Cancer Research  
2014;
3
(6)
:358-359
.

AZD9291

Update on third-generation EGFR tyrosine kinase inhibitors
Jhanelle Gray, Eric Haura
Translational Lung Cancer Research  
2014;
3
(6)
:360-362
.
Is the third generation EGFR TKIs the solution for making EGFR mutant NSCLC a curable disease?
Fred R. Hirsch
Translational Lung Cancer Research  
2014;
3
(6)
:363-364
.
EGFR, EGFR TKI, and EMSI: a never-ending story
Young-Chul Kim
Translational Lung Cancer Research  
2014;
3
(6)
:365-367
.
Recent advances in the development of mutant-selective EGFR inhibitors for non-small cell lung cancer patients with EGFR-TKI resistance
Yung-Hung Luo, Yuh-Min Chen
Translational Lung Cancer Research  
2014;
3
(6)
:368-369
.
Clinical activity of the mutant-selective EGFR inhibitor AZD9291 in patients with EGFR inhibitor—resistant non-small cell lung cancer
Tao Jiang, Caicun Zhou
Translational Lung Cancer Research  
2014;
3
(6)
:370-372
.

Ceritinib

Clinical development and approval of second generation ALK inhibitors for ALK rearranged lung cancer
Daniel B. Costa
Translational Lung Cancer Research  
2014;
3
(6)
:373-375
.
Ceritinib as a promising therapy for ALK related diseases
Monica Ceccon
Translational Lung Cancer Research  
2014;
3
(6)
:376-378
.
Ceritinib—a second-generation ALK inhibitor overcoming resistance in ALK-rearranged non-small cell lung cancer
Sacha I. Rothschild
Translational Lung Cancer Research  
2014;
3
(6)
:379-381
.

Gemcitabine-cisplatin plus necitumumab

Necitumumab: a new therapeutic option for squamous cell lung cancer?
Rathi N. Pillai, Suresh S. Ramalingam
Translational Lung Cancer Research  
2014;
3
(6)
:382-383
.

Onartuzumab plus erlotinib

A critical question for cancer therapy: what new targets exist?
Rafael Rosell, Niki Karachaliou, Jordi Codony, Cristina Teixido, Silvia Garcia-Roman, Daniela Morales, María González Cao, Santiago Viteri, Ignacio Veliz, Yong Loo, Omar Castillo
Translational Lung Cancer Research  
2014;
3
(6)
:384-388
.
Targeting MET in NSCLC: looking for a needle in a haystack
Lorenza Landi, Federico Cappuzzo
Translational Lung Cancer Research  
2014;
3
(6)
:389-391
.
Negative results of METLung study: an opportunity to better understand the role of MET pathway in advanced NSCLC
Maurice Pérol
Translational Lung Cancer Research  
2014;
3
(6)
:392-394
.
Targeting MET and EGFR in NSCLC—what can we learn from the recently reported phase III trial of onartuzumab in combination with erlotinib in advanced non-small cell lung cancer?
Michail Charakidis, Michael Boyer
Translational Lung Cancer Research  
2014;
3
(6)
:395-396
.

Docetaxel (DOC) and ramucirumab

Angiogenesis and lung cancer: ramucirumab prolongs survival in 2nd-line metastatic NSCLC
Millie Das, Heather Wakelee
Translational Lung Cancer Research  
2014;
3
(6)
:397-399
.

Nivolumab

Nivolumab as first line monotherapy for advanced non-small cell lung cancer: could we replace first line chemotherapy with immunotherapy?
Howard West
Translational Lung Cancer Research  
2014;
3
(6)
:400-402
.
Nivolumab (anti-PD-1, BMS-936558, ONO-4538) in patients with advanced non-small cell lung cancer
Arun Rajan, James L. Gulley
Translational Lung Cancer Research  
2014;
3
(6)
:403-405
.

MEDI4736

A phase I study of MEDI4736, NNT-PD-L1 antibody in patients with advanced solid tumors
Christoph C. Zielinski
Translational Lung Cancer Research  
2014;
3
(6)
:406-407
.
A new addition to the PD-1 checkpoint inhibitors for non-small cell lung cancer—the anti-PDL1 antibody—MEDI4736
Sylvia M. Lee, Laura Q. Chow
Translational Lung Cancer Research  
2014;
3
(6)
:408-410
.

MK-3475

Reflections on immune checkpoint inhibition in non-small cell lung cancer
Konstantinos Leventakos, Aaron S. Mansfield
Translational Lung Cancer Research  
2014;
3
(6)
:411-413
.

News

Highlights in the 14th Central European Lung Cancer Conference (CELCC)
Grace Li
Translational Lung Cancer Research  
2014;
3
(6)
:414-419
.

Disclosure:

The focused issue “Personalized Therapy in Lung Cancer” was commissioned by the editorial office, Translational Lung Cancer Research without any sponsorship or funding. Na Zhang, Wen-Zhao Zhong and Yi-Long Wu served as the unpaid Guest Editors for the focused issue.