Patient selection for future lung cancer computed tomography screening programmes: lessons learnt post National Lung Cancer Screening Trial

Successful implementation of low dose CT (LDCT) lung cancer screening, depends on a number of well-researched factors that improve the balance between benefits and harms. One of the most important is the identification of individuals at high risk of developing and dying from lung cancer. There is debate about the threshold that defines high enough risk and the method for estimating risk, with several multivariable risk models available. The findings from the PanCan study shed further light on this topic.