Vol 10, No 6 (June 29, 2021): Translational Lung Cancer Research

Original Article

PD-L1 detection on circulating tumor-derived extracellular vesicles (T-EVs) from patients with lung cancer
Fei Wu, Yanzi Gu, Bin Kang, Fabienne Heskia, Alexandre Pachot, Marc Bonneville, Ping Wei, Ji Liang
Translational Lung Cancer Research  
2021;
10
(6)
:2441-2451
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 (29 June 2021) 
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Artificial intelligence-based analysis for immunohistochemistry staining of immune checkpoints to predict resected non-small cell lung cancer survival and relapse
Haoyue Guo, Li Diao, Xiaofeng Zhou, Jie-Neng Chen, Yue Zhou, Qiyu Fang, Yayi He, Rafal Dziadziuszko, Caicun Zhou, Fred R. Hirsch
Translational Lung Cancer Research  
2021;
10
(6)
:2452-2474
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 (29 June 2021) 
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Increased plasma levels of damage-associated molecular patterns during systemic anticancer therapy in patients with advanced lung cancer
Hiroyuki Inoue, Hirono Tsutsumi, Kentaro Tanaka, Eiji Iwama, Yoshimasa Shiraishi, Aiko Hirayama, Takayuki Nakanishi, Hiroyuki Ando, Maako Nakajima, Seiji Shinozaki, Hiroaki Ogata, Kazuyasu Uryu, Koji Okamura, Shinichi Kimura, Tomohiro Ogawa, Keiichi Ota, Yasuto Yoneshima, Naoki Hamada, Yoichi Nakanishi, Isamu Okamoto
Translational Lung Cancer Research  
2021;
10
(6)
:2475-2486
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 (29 June 2021) 
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Should resection extent be decided by total lesion size or solid component size in ground glass opacity-containing lung adenocarcinomas?
Boyu Lin, Rui Wang, Liang Chen, Zhitao Gu, Chunyu Ji, Wentao Fang
Translational Lung Cancer Research  
2021;
10
(6)
:2487-2499
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 (29 June 2021) 
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Pleural effusions associated with squamous cell lung carcinoma have a low diagnostic yield and a poor prognosis
Michael Dorry, Kevin Davidson, Rajesh Dash, Rachel Jug, Jeffrey M. Clarke, Andrew B. Nixon, Kamran Mahmood
Translational Lung Cancer Research  
2021;
10
(6)
:2500-2508
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 (29 June 2021) 
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Correlation of peripheral blood biomarkers with clinical outcomes in NSCLC patients with high PD-L1 expression treated with pembrolizumab
Amparo Sánchez-Gastaldo, Miguel A. Muñoz-Fuentes, Sonia Molina-Pinelo, Miriam Alonso-García, Laura Boyero, Reyes Bernabé-Caro
Translational Lung Cancer Research  
2021;
10
(6)
:2509-2522
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 (29 June 2021) 
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One carbon metabolism in human lung cancer
Sha Yao, Luogen Peng, Omar Elakad, Stefan Küffer, Marc Hinterthaner, Bernhard C. Danner, Alexander von Hammerstein-Equord, Philipp Ströbel, Hanibal Bohnenberger
Translational Lung Cancer Research  
2021;
10
(6)
:2523-2538
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 (29 June 2021) 
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The clinical impact of three validated PD-L1 immunohistochemistry assays as a prognostic factor in small cell lung cancer
Yong Seok Lee, Jun Hyeok Lim, Wookyung Ryu, Mi Hwa Park, Lucia Kim, Kang Kim, Woo Youl Kim, Hae-Seong Nam
Translational Lung Cancer Research  
2021;
10
(6)
:2539-2550
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 (29 June 2021) 
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Different prognostic implications of hepatic metastasis according to front-line treatment in non-small cell lung cancer: a real-world retrospective study
Myeong Geun Choi, Chang-Min Choi, Dae Ho Lee, Sang-We Kim, Shinkyo Yoon, Woo Sung Kim, Wonjun Ji, Jae Cheol Lee
Translational Lung Cancer Research  
2021;
10
(6)
:2551-2561
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 (29 June 2021) 
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Differences in treatment effect size between progression-free survival and overall survival in anti-PD-1/PD-L1 inhibitors-based trials in advanced NSCLC: a systematic review and meta-analysis
Zhirui Zhou, Shengxiang Ren, Lingxiao Chen, Caicun Zhou, Tao Jiang
Translational Lung Cancer Research  
2021;
10
(6)
:2562-2572
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 (29 June 2021) 
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Randomized phase III study comparing the first-line chemotherapy regimens in patients with driver mutation-negative advanced non-small cell lung cancer and poor performance status complicated with chronic obstructive pulmonary disease
Guoying Gao, Chengzhi Zhou, Yucheng Huang, Ziying Hong, Pei Yu, Ying Chen, Jiabo Gao, Kening Zhang, Zhanhong Xie, Jiexia Zhang, Shiyue Li, Nagata Masashi, Yinyin Qin
Translational Lung Cancer Research  
2021;
10
(6)
:2573-2587
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 (29 June 2021) 
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Evaluation of the reporting quality of clinical practice guidelines on lung cancer using the RIGHT checklist
Yongjie Yang, Jingli Lu, Yanfang Ma, Chen Xi, Jian Kang, Qiwen Zhang, Xuedong Jia, Kefeng Liu, Shuzhang Du, Florian Kocher, Andreas Seeber, Cesare Gridelli, Mariano Provencio, Nobuhiko Seki, Yusuke Tomita, Xiaojian Zhang
Translational Lung Cancer Research  
2021;
10
(6)
:2588-2602
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 (29 June 2021) 
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Video-assisted thoracoscopic surgery for primary lung cancer resections in patients with moderate to severe chronic obstructive pulmonary diseases
Ke Xu, Weipeng Cai, Yuan Zeng, Jingpei Li, Jianxing He, Fei Cui, Jun Liu
Translational Lung Cancer Research  
2021;
10
(6)
:2603-2613
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 (29 June 2021) 
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Immune-related adverse event profile of combination treatment of PD-(L)1 checkpoint inhibitors and bevacizumab in non-small cell lung cancer patients: data from the FDA adverse event reporting system
Shuai Bai, Tiantian Tian, Jose M. Pacheco, Motoko Tachihara, Pingping Hu, Jiandong Zhang
Translational Lung Cancer Research  
2021;
10
(6)
:2614-2624
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 (29 June 2021) 
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Radial endobronchial ultrasound-assisted transbronchial needle aspiration for pulmonary peripheral lesions in the segmental bronchi adjacent to the central airway
Nan Song, Li Yang, Hao Wang, Lei Jiang, Lishu Zhao, Sara Colella, Nikhil Jagan, Francisco A. Almeida, Liang Wu, Ye Gu, Yayi He
Translational Lung Cancer Research  
2021;
10
(6)
:2625-2632
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 (29 June 2021) 
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Consensus

International consensus on severe lung cancer—the first edition
Chengzhi Zhou, Shiyue Li, Jun Liu, Qian Chu, Liyun Miao, Linbo Cai, Xiuyu Cai, Yu Chen, Fei Cui, Yuchao Dong, Wen Dong, Wenfeng Fang, Yong He, Weifeng Li, Min Li, Wenhua Liang, Gen Lin, Jie Lin, Xinqing Lin, Hongbing Liu, Ming Liu, Xinlin Mu, Yi Hu, Jie Hu, Yang Jin, Ziming Li, Yinyin Qin, Shengxiang Ren, Gengyun Sun, Yihong Shen, Chunxia Su, Kejing Tang, Lin Wu, Mengzhao Wang, Huijuan Wang, Kai Wang, Yuehong Wang, Ping Wang, Hongmei Wang, Qi Wang, Zhijie Wang, Xiaohong Xie, Zhanhong Xie, Xin Xu, Fei Xu, Meng Yang, Boyan Yang, Xiangjun Yi, Xiaoqun Ye, Feng Ye, Zongyang Yu, Dongsheng Yue, Bicheng Zhang, Jian Zhang, Jianqing Zhang, Xiaoju Zhang, Wei Zhang, Wei Zhao, Bo Zhu, Zhengfei Zhu, Wenzhao Zhong, Chunxue Bai, Liangan Chen, Baohui Han, Chengping Hu, Shun Lu, Weimin Li, Yong Song, Jie Wang, Caicun Zhou, Jianying Zhou, Yanbin Zhou, Yuichi Saito, Yoshinobu Ichiki, Hitoshi Igai, Satoshi Watanabe, Sara Bravaccini, Alfonso Fiorelli, Francesco Petrella, Takeo Nakada, Piergiorgio Solli, Nikolaos Tsoukalas, Yuki Kataoka, Taichiro Goto, Rossana Berardi, Jianxing He, Nanshan Zhong
Translational Lung Cancer Research  
2021;
10
(6)
:2633-2666
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 (29 June 2021) 
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Review Article

Has programmed cell death ligand-1 MET an accomplice in non-small cell lung cancer?—a narrative review
Wolfram C. M. Dempke, Klaus Fenchel
Translational Lung Cancer Research  
2021;
10
(6)
:2667-2682
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 (29 June 2021) 
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The multiple roles and therapeutic potential of clusterin in non-small-cell lung cancer: a narrative review
Juofang Tan, Wei Guo, Su Yang, Dingpei Han, Hecheng Li
Translational Lung Cancer Research  
2021;
10
(6)
:2683-2697
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 (29 June 2021) 
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A narrative review of the migration and invasion features of non-small cell lung cancer cells upon xenobiotic exposure: insights from in vitro studies
Catarina Albuquerque, Rita Manguinhas, João G. Costa, Nuno Gil, Jordi Codony-Servat, Matilde Castro, Joana P. Miranda, Ana S. Fernandes, Rafael Rosell, Nuno G. Oliveira
Translational Lung Cancer Research  
2021;
10
(6)
:2698-2714
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 (29 June 2021) 
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Consistency of recommendations for the diagnosis and treatment of non-small cell lung cancer: a systematic review
Zhe Zhang, Sen Yang, Yanfang Ma, Hanqiong Zhou, Xuan Wu, Jing Han, Jiabao Hou, Lidan Hao, Jonathan D. Spicer, Young Wha Koh, Mariano Provencio, Noemi Reguart, Tetsuya Mitsudomi, Qiming Wang
Translational Lung Cancer Research  
2021;
10
(6)
:2715-2732
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 (29 June 2021) 
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Editorial on Lung Cancer and The Immune System1

Lung cancer and the immune system—current controversies and future opportunities
Daniel P. Steinfort
Translational Lung Cancer Research  
2021;
10
(6)
:2733-2735
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 (29 June 2021) 
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Review Article on Lung Cancer and The Immune System1

Immunotherapy in oncogene addicted non-small cell lung cancer
Luke McLean, Jose Luis Leal, Benjamin J. Solomon, Thomas John
Translational Lung Cancer Research  
2021;
10
(6)
:2736-2751
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 (29 June 2021) 
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The knowns & unknowns of pulmonary toxicity following immune checkpoint inhibitor therapies: a narrative review
Alistair R. Miller, Renee Manser
Translational Lung Cancer Research  
2021;
10
(6)
:2752-2765
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 (29 June 2021) 
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A narrative review of combined stereotactic ablative radiotherapy and immunotherapy in metastatic non-small cell lung cancer
Zarique Z. Akanda, Paul J. Neeson, Thomas John, Stephen Barnett, Gerard G. Hanna, Alistair Miller, Ross Jennens, Shankar Siva
Translational Lung Cancer Research  
2021;
10
(6)
:2766-2778
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 (29 June 2021) 
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Integrating endobronchial ultrasound bronchoscopy with molecular testing of immunotherapy biomarkers in non-small cell lung cancer
Steven Bozinovski, Amanda Vannitamby, Kanishka Rangamuwa, Savreet Aujla, Hao Wang, Christian Aloe, Louis Irving, Tracy T. Leong, Daniel P. Steinfort
Translational Lung Cancer Research  
2021;
10
(6)
:2779-2787
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 (29 June 2021) 
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Exploring natural killer cell immunology as a therapeutic strategy in lung cancer
Jonas B. Hess, Kate D. Sutherland, Sarah A. Best
Translational Lung Cancer Research  
2021;
10
(6)
:2788-2805
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 (29 June 2021) 
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Emerging and multifaceted role of neutrophils in lung cancer
Christian Aloe, Hao Wang, Ross Vlahos, Louis Irving, Daniel Steinfort, Steven Bozinovski
Translational Lung Cancer Research  
2021;
10
(6)
:2806-2818
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 (29 June 2021) 
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Holding our breath: the promise of tissue-resident memory T cells in lung cancer
Claire Marceaux, Clare E. Weeden, Claire L. Gordon, Marie-Liesse Asselin-Labat
Translational Lung Cancer Research  
2021;
10
(6)
:2819-2829
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 (29 June 2021) 
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B cells in lung cancer—not just a bystander cell: a literature review
Tracy L. Leong, Vanessa L. Bryant
Translational Lung Cancer Research  
2021;
10
(6)
:2830-2841
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 (29 June 2021) 
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Thermal ablation in non-small cell lung cancer: a review of treatment modalities and the evidence for combination with immune checkpoint inhibitors
Kanishka Rangamuwa, Tracy Leong, Clare Weeden, Marie-Liesse Asselin-Labat, Steven Bozinovski, Michael Christie, Tom John, Phillip Antippa, Louis Irving, Daniel Steinfort
Translational Lung Cancer Research  
2021;
10
(6)
:2842-2857
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 (29 June 2021) 
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Brief Report on Lung Cancer and The Immune System1

Increase in tumour PD-L1 expression in non-small cell lung cancer following bronchoscopic thermal vapour ablation
Kanishka Rangamuwa, Tracy Leong, Steven Bozinovski, Michael Christie, Thomas John, Phillip Antippa, Louis Irving, Daniel Steinfort
Translational Lung Cancer Research  
2021;
10
(6)
:2858-2864
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 (29 June 2021) 
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Editorial on Immunotherapy in Other Thoracic Malignancies and Uncommon Populations2

Immunotherapy in other thoracic malignancies and uncommon populations
Jordi Remon, Benjamin Besse
Translational Lung Cancer Research  
2021;
10
(6)
:2865-2867
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 (29 June 2021) 
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Review Article on Immunotherapy in Other Thoracic Malignancies and Uncommon Populations2

Is there any opportunity for immune checkpoint inhibitor therapy in non-small cell lung cancer patients with brain metastases?
Lizza E. L. Hendriks, Jordi Remon, Jessica Menis, Benjamin Besse
Translational Lung Cancer Research  
2021;
10
(6)
:2868-2875
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 (29 June 2021) 
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Exploring the immune-checkpoint inhibitors’ efficacy/tolerability in special non-small cell lung cancer (NSCLC) populations: focus on steroids and autoimmune disease
Francesco Passiglia, Valeria Cetoretta, Marco De Filippis, Valerio Napoli, Silvia Novello
Translational Lung Cancer Research  
2021;
10
(6)
:2876-2889
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 (29 June 2021) 
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Original Article on Immunotherapy in Other Thoracic Malignancies and Uncommon Populations2

Immune checkpoint inhibitors in oncogene-addicted non-small cell lung cancer: a systematic review and meta-analysis
Giorgia Guaitoli, Marcello Tiseo, Massimo Di Maio, Luc Friboulet, Francesco Facchinetti
Translational Lung Cancer Research  
2021;
10
(6)
:2890-2916
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 (29 June 2021) 
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First-line immunotherapy in non-small cell lung cancer patients with poor performance status: a systematic review and meta-analysis
Francesco Facchinetti, Massimo Di Maio, Fabiana Perrone, Marcello Tiseo
Translational Lung Cancer Research  
2021;
10
(6)
:2917-2936
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 (29 June 2021) 
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Review Article on Immunotherapy in Other Thoracic Malignancies and Uncommon Populations2

Current and future biomarkers for outcomes with immunotherapy in non-small cell lung cancer
Boris Duchemann, Jordi Remon, Marie Naigeon, Lydie Cassard, Jean Mehdi Jouniaux, Lisa Boselli, Jonathan Grivel, Edouard Auclin, Aude Desnoyer, Benjamin Besse, Nathalie Chaput
Translational Lung Cancer Research  
2021;
10
(6)
:2937-2954
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 (29 June 2021) 
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Novel patterns of progression upon immunotherapy in other thoracic malignancies and uncommon populations
Roberto Ferrara, Diego Signorelli, Claudia Proto, Arsela Prelaj, Marina Chiara Garassino, Giuseppe Lo Russo
Translational Lung Cancer Research  
2021;
10
(6)
:2955-2969
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 (29 June 2021) 
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Immunotherapy in small cell lung cancer: one step at a time: a narrative review
Daphne W. Dumoulin, Anne-Marie C. Dingemans, Joachim G. J. V. Aerts, Jordi Remon, Dirk K. M. De Ruysscher, Lizza E. L. Hendriks
Translational Lung Cancer Research  
2021;
10
(6)
:2970-2987
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 (29 June 2021) 
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Immunotherapy in malignant pleural mesothelioma: a review of literature data
Jessica Menis, Giulia Pasello, Jordi Remon
Translational Lung Cancer Research  
2021;
10
(6)
:2988-3000
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 (29 June 2021) 
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Narrative review of immunotherapy in thymic malignancies
Jose Carlos Benitez, Benjamin Besse
Translational Lung Cancer Research  
2021;
10
(6)
:3001-3013
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 (29 June 2021) 
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Immune checkpoint inhibitors in elderly patients treated for a lung cancer: a narrative review
Charles Naltet, Benjamin Besse
Translational Lung Cancer Research  
2021;
10
(6)
:3014-3028
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 (29 June 2021) 
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Erratum

Erratum to pembrolizumab-induced myocarditis in a patient with malignant mesothelioma: plasma exchange as a successful emerging therapy—case report
Editorial Office
Translational Lung Cancer Research  
2021;
10
(6)
:3029
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 (29 June 2021) 
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Disclosure:

1. The series “Lung Cancer and The Immune System” was commissioned by the Editorial office, Translational Lung Cancer Research without any sponsorship or funding. Daniel Steinfort served as the unpaid Guest Editor for the series.

2. The series “Immunotherapy in other thoracic malignancies and uncommon populations” was commissioned by the Editorial office, Translational Lung Cancer Research without any sponsorship or funding.