Vol 14, No 3 (March 31, 2025) - Translational Lung Cancer Research

Editorial Commentary

Will INSPIRE crown iruplinalkib as a new standard choice in first-line advanced ALK-positive non-small cell lung cancer?

Blerina Resuli, Diego Kauffmann-Guerrero

PDF Pages: 653-656 Full Text (143) Peer Review File COI Form Open Access

Optimizing long-term treatment with ALK inhibitors: balancing efficacy and safety

Ayuka Dai, Takaaki Sasaki

PDF Pages: 657-661 Full Text (160) Peer Review File COI Form Open Access

Original Article

ANKRD11 as a potential biomarker for brain metastasis from lung adenocarcinoma via cerebrospinal fluid liquid biopsy

Qinhong Sun, Peng Xing, Qinglin Wang, Zhijun Xia, Jianyu Li, Zhitong Li, Fancheng Meng, Tongyan Liu, Siwei Wang, Rong Yin

PDF Pages: 662-676 Full Text (186) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Persistent and novel changes in plasma microRNA profiles in patients with non-small cell lung cancer following tumour resection

Maria Sromek, Maciej Głogowski, Magdalena Chechlińska, Mariusz Kulińczak, Michalina Zajdel, Natalia Żeber-Lubecka, Aneta Bałabas, Łukasz M. Szafron, Maria Kulecka, Jan K. Siwicki

PDF Pages: 677-706 Full Text (122) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Amivantamab as a salvage therapy post-EGFR-tyrosine kinase inhibitor failure in patients with mutated EGFR non-small cell lung cancer

Bilal Krayim, Waleed Kian, Maria Spector, Inbal Granot, Julia Dudnik, Michal Nissim, Dolev Kahala, Areen Abu Remilah, Naama R. Bogot, Gleb Kornev, Noam Asna, Nir Peled, Laila C. Roisman

PDF Pages: 707-717 Full Text (155) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Circulating lung cancer exosomes damage the niche of intestinal stem cells

Ke Wang, Lu Xu, Jianhua Feng, Shubin Wang, Xi Wang, Junyi Zou, Zhenni Xu, Lingxiao Huang, Wenjun Jiang, Jin Zhou, Xudan Lei, Dengqun Liu

PDF Pages: 718-735 Full Text (97) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Predicting survival in small cell lung cancer patients undergoing various treatments: a machine learning approach

Ziran Zhao, Xi Cheng, Yibo Gao, Fengwei Tan, Qi Xue, Shugeng Gao, Jie He

PDF Pages: 736-748 Full Text (132) Reporting Checklist Peer Review File COI Form Open Access

Prognostic significance of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in second-line immunotherapy for patients with non-small cell lung cancer

Magdalena Knetki-Wróblewska, Aleksandra Grzywna, Paweł Krawczyk, Kamila Wojas-Krawczyk, Izabela Chmielewska, Tomasz Jankowski, Janusz Milanowski, Maciej Krzakowski

PDF Pages: 749-760 Full Text (135) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Connecting the dots: (RANKL⁺) extracellular vesicle count in blood plasma in relation to bone metastases, skeletal related events and osimertinib treatment in patients with EGFR mutated non-small cell lung cancer

Anita J. W. M. Brouns, Iris J. Robbesom-van den Berge, Sophie M. Ernst, Christi M. J. Steendam, Wouter W. Woud, Liang Wu, Anne-Marie C. Dingemans, Lizza E. L. Hendriks, Marjolein van Driel

PDF Pages: 761-774 Full Text (79) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

A better option for localization of multiple pulmonary nodules in the ipsilateral lung: electromagnetic navigation bronchoscopy-guided preoperative localization

Rui Wang, Yongjiang Chen, Chudong Wang, Zijian Li, Yunpeng Zhong, Yunjuan Liang, Shuben Li

PDF Pages: 775-784 Full Text (107) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Short-term peri- and intra-tumoral CT radiomics to predict immunotherapy response in advanced non-small cell lung cancer

Ting Wang, Lei Chen, Xiao Bao, Zijuan Han, Zezhou Wang, Shengdong Nie, Yajia Gu, Jing Gong

PDF Pages: 785-797 Full Text (86) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Diagnostic utility of bronchoscopy for newly emerging peripheral pulmonary lesions after pulmonary resection

Takahiro Suzuki, Yuji Matsumoto, Hideaki Furuse, Keigo Uchimura, Tatsuya Imabayashi, Takaaki Tsuchida

PDF Pages: 798-809 Full Text (72) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Closer proximity of pre-treatment CD4⁺ T cells to CD8⁺ T cells favor response to neoadjuvant immunotherapy in patients with PD-L1 low-expressing non-small cell lung cancer

Liying Yang, Jiaxiao Geng, Hao Yang, Miaoqing Zhao, Hongtu Yuan, Yushan Yan, Li Wu, Fanghan Cao, Ligang Xing, Xiaorong Sun

PDF Pages: 810-823 Full Text (119) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Single cell RNA-seq and bulk RNA-seq analysis identifies MUC1 as a key gene for lung adenocarcinoma to neuroendocrine transformation

Hongxia Li, Tiantian Yang, Yu Chen, Zhiqin Xie

PDF Pages: 824-841 Full Text (177) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Nomogram based on computed tomography radiomics features and clinicopathological factors to predict the prognosis of patients with non-small cell lung cancer receiving immune checkpoint inhibitor rechallenge

Junfeng Zhao, Ying Li, Ruyue Li, Xiujing Yao, Xue Dong, Lin Su, Yintao Li

PDF Pages: 842-856 Full Text (100) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Integrated multiomics machine learning and mediated Mendelian randomization investigate the molecular subtypes and prognosis lung squamous cell carcinoma

Zhanghao Huang, Jing Li, You Lang Zhou, Jiahai Shi

PDF Pages: 857-877 Full Text (83) Reporting Checklist Peer Review File COI Form Open Access

Targeting of arachidonic acid-modulated autophagy to enhance the sensitivity of ROS1⁺ or ALK⁺ non-small cell lung cancer to crizotinib therapy

Hui Jie, Hongjin Lai, Zihuai Wang, Min Yi, Yi Liu, Edyta Maria Urbanska, Eric Santoni-Rugiu, Shiyou Wei, Yuhao Chen, Chuan Li, Tengyong Wang, Nanzhi Luo, Lunxu Liu, Senyi Deng, Chenglin Guo

PDF Pages: 878-896 Full Text (164) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Enhancing the precision of auxiliary diagnosis for lung cancer through use of SHOX2 and RASSF1A methylation status in lung biopsy and lymph node biopsy specimens

Ping Gu, Yue Wang, Chunlei Shi, Yuqing Chen, Jialin Qian, Yanjie Niu, Hai Zhang, Yunxia Bao, Bin She, Xiaosha Ren, Iyare Izevbaye, Baohui Han, Hua Zhong, Yu Dong

PDF Pages: 897-911 Full Text (88) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Analysis of baseline interstitial lung abnormality on the risk of checkpoint inhibitor-related pneumonitis and survival in advanced non-small cell lung cancer patients treated with first-line PD-1/PD-L1 inhibitors

Yu Li, Shuo Liang, Yanjun Du, Jun Yao, Yuxin Jiang, Wanjun Lu, Qiuxia Wu, Fumihiro Yamaguchi, Marko Jakopović, Wolfgang M. Brueckl, Dong Wang, Fang Zhang, Qin Wang, Tangfeng Lv, Ping Zhan

PDF Pages: 912-930 Full Text (110) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Palliative surgery is effective in patients with EGFR-mutant lung adenocarcinoma with pleural metastasis

Yue Liu, Yifei Zhou, Shuangyi Li, Qianxin Zhou, Jun Li, Nobuhiro Kanaji, Sara Ricciardi, Raja M. Flores, Marcello Migliore, Kakeru Hisakane, Yuming Zhu, Wenxin He, Linsong Chen, Dongliang Bian

PDF Pages: 931-939 Full Text (106) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Identification and validation of crotonylation-related diagnostic markers for lung adenocarcinoma via weighted correlation network analysis and machine learning

Bowen Hu, Xin Chen, Dan Zou, Xiaoyue Du, Sitong Feng, Yiwen Shen, Xiaofeng Sha, Feng Jiang, Guoren Zhou, Fan Lin, Lukas Käsmann, Bo Shen

PDF Pages: 940-962 Full Text (113) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Neoadjuvant immunochemotherapy demonstrated improved efficacy and comparable safety to neoadjuvant chemotherapy for limited-stage small-cell lung cancer: a cohort study

Lijiang Song, Xiaowei Mao, Haichuan Hu, Hu Zhang, Xinxin Ying, Lichen Zhang, Kai Liu, Huiyong Han, Dongde Li, Zhengfu He

PDF Pages: 963-974 Full Text (117) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Review Article

Recent advancements in lung cancer research: a narrative review

Fuk Hay Tang, Heylie Y. T. Wong, Phyllis S. W. Tsang, Mabel Yau, Shing Yau Tam, Lawla Law, Katherine Yau, Jade Wong, Fatema Hassan Mustafa Farah, Jacky Wong

PDF Pages: 975-990 Full Text (197) Reporting Checklist Peer Review File COI Form Open Access

Multidisciplinary management of N2 stage III non-small cell lung cancer: opportunities and challenges for radiation oncology

Hongcheng Zhu, Daniel G. Schep, Marta Isolano, Piergiorgio Muriana, Sarayut L. Geater, Giulia Veronesi, Fangqiu Fu, Roberto Ferrara, Kuaile Zhao, Alexander V. Louie

PDF Pages: 991-1006 Full Text (87) Peer Review File COI Form Open Access