Vol 15, No 7 (July 31, 2026): Translational Lung Cancer Research

Original Article

CT-derived abdominal organ volumetrics for predicting recurrence-free and disease-free survival in resected non-small cell lung cancer: a multicenter retrospective cohort study
Huanli Huang, Bingxin Gong, Jie Lou, Dezhi Zhu, Yusheng Guo, Gang Xiang, Shu Peng, Wei Li, Hanxiao Li, Lian Yang
Translational Lung Cancer Research  
2026;
15
(7)
:194
.
Real-world analysis in patients with limited-stage small-cell lung cancer who received durvalumab after concurrent chemoradiotherapy
Jiayi Yu, Xue Yang, Jiahui Shan, Dan Yang, Xiao Chang, Leilei Jiang, Liuhua Long, Yue Teng, Xin Dong, Rong Yu, Huiming Yu, Jun Zhao, Shaohua Ma, Anhui Shi
Translational Lung Cancer Research  
2026;
15
(7)
:195
.
Multiplexed quantitative proteomics in small-cell lung cancer: stage-linked DLL3 distribution and an independent prognostic signal of thymidine phosphorylase
Tae-Eun Kim, Sook Hee Hong, Ho Jung An, Jeong Uk Lim, Chan Kwon Park, Hyoung Kyu Yoon, Young Jo Sa, Hyo Rim Kim, Tae-Jung Kim
Translational Lung Cancer Research  
2026;
15
(7)
:196
.
Tertiary lymphoid structures predict the neoadjuvant chemoimmunotherapy response of stage III non-small cell lung cancer
Guibing Ren, Yajing Qu, Hainan Li, Zhihong Li, Yanyan Gao, Xiaoxiong Shi, Xiaoru Meng, Pengpeng Xu, Weihao Hu, Ningbo Liu, Lili Huo, Jing Luo
Translational Lung Cancer Research  
2026;
15
(7)
:197
.
Promising benefits of MET inhibition combined with EGFR/ALK tyrosine kinase inhibitor in heavily treated non-small cell lung cancer patients with EGFR-mutant/ALK rearrangement and MET overexpression: a retrospective cohort study
Qianxin Zhou, Jianing Qiu, Haizhou Yue, Dongsheng Xu, Shuyan Meng
Translational Lung Cancer Research  
2026;
15
(7)
:198
.
Development and validation of a machine learning model for predicting objective response to PD-1 inhibitors in lung cancer patients
Weiqi Chen, Xiaojie Zhao, Zhuojia Li, Xingshan Kong, Furong Li, Zhiyuan He, Jingwen Chen, Qinglin Xiao, Beixin Yu, Bo Wu, Caifang Zeng
Translational Lung Cancer Research  
2026;
15
(7)
:199
.
Intratumor immune heterogeneity across simulated core biopsy sizes in non-small cell lung cancer: an exploratory study
Shaowen Lyu, Kobe Reynders, Iris E. W. G. Laven, Christel Faes, Birgit Weynand, Lisa M. Hillen, Paul De Leyn, Lizza E. L. Hendriks, Els Wauters, Maarten Lambrecht, Rianne D. W. Vaes, Dirk De Ruysscher
Translational Lung Cancer Research  
2026;
15
(7)
:200
.
Elevated serum neuron-specific enolase as an indicator of poor chemo-immunotherapy outcomes and reduced CD8-positive lymphocyte infiltration in small-cell lung cancer: a retrospective cohort study
Yuta Koshino, Naoki Shijubou, Toshiyuki Sumi, Terufumi Kubo, Kenta Sasaki, Rena Morita, Kenji Murata, Tomohide Tsukahara, Kotomi Terai, Shintaro Sugita, Tatsuru Ikeda, Yuichi Yamada, Hirofumi Chiba, Yoshihiko Hirohashi
Translational Lung Cancer Research  
2026;
15
(7)
:201
.
FOXA1 drives chemoresistance through activating Wnt pathway in small cell lung cancer
Deshen Pan, Keihong Wei, Luoyan Sheng, Qing Gao, Chaoliang Xu, Yufei Xi, Deshui Jia, Yan Zhang
Translational Lung Cancer Research  
2026;
15
(7)
:202
.
Longevity-associated FOXO3 genotype mitigates the risk of lung cancer after smoking cessation: a prospective cohort study
Randi Chen, Timothy A. Donlon, Vanessa L. Cunanan, Kaon Fong, Keisuke Miyamoto, Bradley J. Willcox, Kamal H. Masaki
Translational Lung Cancer Research  
2026;
15
(7)
:203
.
Non-destructive three-dimensional structural assessment of transbronchial cryobiopsy specimens using phase-contrast X-ray CT: a proof-of-concept study
Yuji Matsumoto, Akio Yoneyama, Rika Baba, Hideaki Furuse, Tatsuya Imabayashi, Shigehiro Yagishita, Takaaki Tsuchida
Translational Lung Cancer Research  
2026;
15
(7)
:204
.
A retrospective cohort study integrating invasive mucinous adenocarcinoma into the IASLC grading system for lung adenocarcinoma
Hanyue Li, Haoran Liu, Hui Shi, Rongji Mu, Lei Xu, Wentao Fang, Teng Mao
Translational Lung Cancer Research  
2026;
15
(7)
:205
.
Baseline IL-6, IL-8, IFN-ω, and perforin as prognostic biomarkers in immune checkpoint inhibitor-treated metastatic non-small cell lung cancer
Varshini Odayar, Hyojung Jang, Ashley Pearson, Jadyn James, Emily Kloska, Benjamin H. Singer, Shadia Jalal, Charles J. Nock, Lili Zhao, Michael Green, Nithya Ramnath
Translational Lung Cancer Research  
2026;
15
(7)
:206
.
Treatment patterns and outcomes of later-line therapy in advanced non-small cell lung cancer with unknown or no actionable genomic alterations: a multicenter real-world study in China (RECAP study)
Hanxiao Chen, Xiangjiao Meng, Ling Cai, Wei Lei, Yu Tang, Xi Shi, Leilei Ma, Jun Zhao
Translational Lung Cancer Research  
2026;
15
(7)
:207
.
Best supportive care in stage I–III non-small cell lung cancer: survival by reason for curative treatment omission in a real-world study population
Guus R. M. van den Heuvel, Bas L. R. Mandos, Hans J. M. Smit, Olga C. J. Schuurbiers, Francesco Ciompi, Erik H. J. G. Aarntzen, Kaamar Azijli, Iris Walraven, Michel M. van den Heuvel
Translational Lung Cancer Research  
2026;
15
(7)
:208
.
Development and validation of machine learning diagnostic models integrating clinical, CT, and laboratory features to differentiate lung cancer from pulmonary tuberculosis in patients with solitary pulmonary nodules: a single-center retrospective study
Yuhang Li, Weijun Wu, Huiling Xu, Jun Ma, Minwei Bao, Junjie Zhu, Shanhao Chen
Translational Lung Cancer Research  
2026;
15
(7)
:209
.
Predictors of prolonged hospital stay in patients with lung cancer undergoing sublobar resection
Liang Xia, Xiaohu Hao, Ruichen Cui, Jiahan Cheng, Minzhang Guo, Wenjing Zhou, Shasha Li, Qiang Pu, Yunke Zhu
Translational Lung Cancer Research  
2026;
15
(7)
:210
.
Association of symptoms at diagnosis with prognosis in patients with surgically treated stage I non-small cell lung cancer: a retrospective cohort analysis of a prospectively maintained registry
Jiahan Cheng, Ruichen Cui, Xiaohu Hao, Xiangchao Kong, Wenjing Zhou, Shasha Li, Qiang Pu, Yunke Zhu
Translational Lung Cancer Research  
2026;
15
(7)
:211
.

Study Protocol

Neoadjuvant befotertinib plus vorolanib in resectable stage II–IIIB EGFR-mutant NSCLC: a study protocol for the prospective, single-arm phase I/II trial
Leilei Wu, Lei Cai, Da Chen, Sheng Chen, Xiancong Huang, Qiqi Yang, Jinshi Liu, Qixun Chen, Xun Yang, Qiang Zhao, Taobo Luo, Jian Zeng
Translational Lung Cancer Research  
2026;
15
(7)
:212
.

Review Article

Epigenetics in lung cancer precision medicine: from bench to bedside—a narrative review
Jianbo Zhou, Yue Pan, Guangzhi Ma, Gang Yuan
Translational Lung Cancer Research  
2026;
15
(7)
:213
.
Deciphering lung cancer at high resolution: a narrative review of applications of single-cell and spatial transcriptomics sequencing
Qian Zheng, Peiji Yao, Qiyu Zhu, Jingwei Li, Wenrong Liu, Jiaxuan Wu, Xiaolong Tang, Weiya Wang, Jiadi Gan, Weimin Li, Chengdi Wang
Translational Lung Cancer Research  
2026;
15
(7)
:214
.
Immune-preserving radiotherapy and perioperative immunotherapy in stage III NSCLC: a narrative review of current management and future directions for IIIA/IIIB NSCLC
Zeta Chow, Charles B. Simone II, Haibo Lin, Jun Yang, Mark Bernard, Weisi Yan
Translational Lung Cancer Research  
2026;
15
(7)
:215
.
Role and clinical significance of VISTA (PD-1H) and PVR (CD155) expression in non-small cell lung carcinoma: a systematic review
Maciej Baron, Piotr Lewandowski, Iwona Jabłońska, Andrzej Skrzypiec, Kamil Liberka, Marcin Fyrla, Bartosz Bula, Bogna Drozdzowska
Translational Lung Cancer Research  
2026;
15
(7)
:216
.
Targeted therapeutic strategies for KRAS-G12D-mutant non-small cell lung cancer: a narrative review
Yihan Chen, Meiling Chen, Yixin Xia, Jinliang Chen
Translational Lung Cancer Research  
2026;
15
(7)
:217
.