Vol 15, No 3 (March 23, 2026) - Translational Lung Cancer Research

Original Article

A radiomics nomogram integrated with radiological features for preoperative prediction of lung nodule invasiveness: comparison with Lung-RADS

Siwei Miao, Zhaojie Han, Fei Wang, Shengwei Liu, Ying Li, Kun Li, Hongqian Wang, Shuaixiang Gao, Xiaolin Xiong, Hao Luo, Chencui Huang, Yang Qiu, Peng Wang, Haidong Wang

Translational Lung Cancer Research

2026;

(3)

:46

(23 March 2026)

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Lightweight hybrid foundation model for lung cancer prognosis based on low-dose chest X-ray images

Helen Haile Hayeso, Zenebe Markos Lonseko, Fahad Mushabbab G. Alotaibi, Tao Gan, Peifeng Shi, Shuqi Dong, Nini Rao

Translational Lung Cancer Research

2026;

(3)

:47

(23 March 2026)

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Adjuvant chemotherapy for completely resected stage IB–IIA non-small cell lung cancer according to the AJCC 8th edition staging system: a real-world retrospective cohort study based on the SEER database

Zewen Sun, Changtai Zhao, Kexin Feng, Geyun Chang, Jingwei Zhang, Yan Ju, Fan Yang, Xiang Yan, Xiao Li

Translational Lung Cancer Research

2026;

(3)

:48

(23 March 2026)

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Development and validation of a habitat-based computed tomography radiomics model for differentiating isolated lung cancer, isolated tuberculoma, and coexistence of tuberculosis with lung cancer: a dual-center retrospective study

Ning Shi, Zhenzhen Wan, Limin Wen, Zhenpeng Liu, Bing Wang, Ye Li, Peng Xiong, Dailun Hou, Xiuling Liu

Translational Lung Cancer Research

2026;

(3)

:49

(23 March 2026)

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Molecular and clinical disparity of EGFR-mutant non-small cell lung cancer (NSCLC) based on histopathological stage and EGFR molecular subtypes

Dayoung Yoon, Ji Won Lee, Byoung Chul Cho, Eun Joo Kang, Jung Sun Kim, Taekyu Lim, Seong Yoon Yi, Yu Jung Kim, Mi Sun Ahn, Young Saing Kim, Ji Hyun Park, Seungtaek Lim, Hyung Soon Park, Jang Ho Cho, Byunghyun Jang, Ji Yoon Lee, Jiwon Kim, Jisoo Hong, Harim Koo, Seok Chung, Sang Won Shin, Yeul Hong Kim, Jason K. Sa, Yoon Ji Choi

Translational Lung Cancer Research

2026;

(3)

:50

(23 March 2026)

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Proposal on incorporating consolidation-to-tumor ratio into the clinical T1 classification in patients with invasive lung adenocarcinoma

Molin Zhang, Chaoqiang Deng, Fangqiu Fu, Ting Ye, Akif Turna, Yuan Li, Yang Zhang, Haiquan Chen

Translational Lung Cancer Research

2026;

(3)

:51

(23 March 2026)

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Effect of cold ischemia time and storage temperature on anaplastic lymphoma kinase (ALK) expression in surgically resected lung cancer specimens

Ryuichi Yoshimura, Naoki Yanagawa, Noriyuki Yamada, Makoto Tomoyasu, Wataru Shigeeda, Yuka Kaneko, Ryotaro Endo, Hironaga Kanno, Hiroyuki Deguchi, Hajime Saito

Translational Lung Cancer Research

2026;

(3)

:52

(23 March 2026)

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A novel maximum wall thickness (Tmax) category for cystic lung adenocarcinomas: a retrospective study focusing on pathological invasiveness and prognosis

Beinuo Wang, Jin Pu, Jian Zhou, Zhenghao Dong, Xiang Lin, Yu Tong, Chunchao Xia, Hu Liao

Translational Lung Cancer Research

2026;

(3)

:53

(23 March 2026)

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Prognostic impact of thyroid transcription factor-1 expression and the efficacy of carboplatin plus (nab-) paclitaxel in non-squamous non-small cell lung cancer complicated with idiopathic interstitial pneumonias

Yuto Terashima, Aya Fukuizumi, Koichiro Kamio, Iori Abe, Erika Miyake, Keiki Miyadera, Yasuhiro Kato, Kakeru Hisakane, Shinji Nakamichi, Susumu Takeuchi, Akihiko Miyanaga, Yasuhiro Terasaki, Kazuo Kasahara, Masahiro Seike

Translational Lung Cancer Research

2026;

(3)

:54

(23 March 2026)

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NOTCH4 as a driver of epithelial-mesenchymal transition, angiogenesis, and stromal remodeling in lung adenocarcinoma: integrated transcriptomic and protein-level validation

Young Wha Koh, Jae-Ho Han, Seokjin Haam, Hyun Woo Lee

Translational Lung Cancer Research

2026;

(3)

:55

(23 March 2026)

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Retrospective study of alectinib treatment among variants of ALK fusion in lung adenocarcinoma

Yuma Watanabe, Ayako Takigami, Shu Hisata, Masayuki Nakayama, Naoko Mato, Makoto Maemondo

Translational Lung Cancer Research

2026;

(3)

:56

(23 March 2026)

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Real-time breath metabolomics as catalyst for personalized lung cancer diagnostics: prospective matched case-control trial (LUCAbreath)

Felix Schmidt, Diego M. Baur, Patrick Baumgartner, Jonas Herth, Kai Fricke, Noriane A. Sievi, Kapil Dev Singh, Thomas Gaisl, Alice Huang, Daniel Franzen, Silvia Ulrich, Pablo Sinues, Malcolm Kohler

Translational Lung Cancer Research

2026;

(3)

:57

(23 March 2026)

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Development of a deep learning model based on computed tomography automatic segmentation to assist in selecting optimal time-to-surgery and dissected lymph node count for non-small cell lung cancer patients undergoing neoadjuvant immunotherapy and chemotherapy: a multicenter study

Junfeng Zhao, Ying Li, Jiaxuan Chen, Chuankun Han, Yifei Yan, Chen Zhou, Yingrui Bai, Yali Xu, Yintao Li

Translational Lung Cancer Research

2026;

(3)

:58

(23 March 2026)

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Effectiveness and safety of combination immunotherapy with or without ipilimumab according to PD-L1 expression in patients with non-small cell lung cancer: a multi-center retrospective cohort study

Akio Nomura, Takeshi Masuda, Kiyofumi Shimoji, Shun Takao, Yusuke Izumi, Yusuke Araki, Yusuke Takayama, Ken Masuda, Kakuhiro Yamaguchi, Shinjiro Sakamoto, Yasushi Horimasu, Taku Nakashima, Hiroshi Iwamoto, Tadashi Senoo, Hiroyasu Shoda, Nobuhisa Ishikawa, Masahiro Yamasaki, Hironobu Hamada, Morihito Okada, Noboru Hattori

Translational Lung Cancer Research

2026;

(3)

:59

(23 March 2026)

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Neoadjuvant or conversion anti-PD-1/PD-L1 immunotherapy combined with chemotherapy improves 2-year survival and achieves high pathological complete response rate in patients with stage IIB–IIIB small-cell lung cancer

Zhiyuan Gao, Zhengxuan Li, Xin Yao, Changjian Shao, Jia Chen, Zenghui Fan, Jinbo Zhao, Jian Wang, Yunfeng Ni, Mingliang Xing, Xiaolong Yan

Translational Lung Cancer Research

2026;

(3)

:60

(23 March 2026)

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Prognostic implications of dominant lesion misidentification in multiple primary lung cancer

Bowen Zhao, Xiaoyun Su, Yu Huang, Xiaoyu Han, Yan Li, Chi Zhang, Zuhan Gen, Qiuyu Len, Shiwen He, Shiwen Fan, Ming Chen, Kuo Li, Fan Yang, Guangyao Wu, Yongde Liao