Vol 14, No 2 (February 28, 2025): Translational Lung Cancer Research

Editorial Commentary

Light on the horizon for HER2 overexpressing non-small cell lung cancer?
Kira-Lee Koster, Martin Früh
Translational Lung Cancer Research  
2025;
14
(2)
:305-309
.
Alectinib impressively enters the adjuvant setting for early-stage ALK-rearranged non-small cell lung cancer and outperforms chemotherapy—let’s define who benefits the most
Eric Santoni-Rugiu, Jens Benn Sørensen, Edyta Maria Urbanska
Translational Lung Cancer Research  
2025;
14
(2)
:310-313
.
Trastuzumab deruxtecan in HER2 overexpressing non-small cell lung cancer (NSCLC)
Omali Pitiyarachchi, Aaron C. Tan
Translational Lung Cancer Research  
2025;
14
(2)
:314-322
.
Will “Sun”-WUKONG, the monkey king, conquer EGFR exon 20 insertion mutation positive non-small cell lung cancer?
Molly Li, Ross A. Soo
Translational Lung Cancer Research  
2025;
14
(2)
:323-327
.
Novel immune checkpoint inhibitor strategies in advanced non-small cell lung cancer: towards biomarker-driven therapies?
M. Benthe Muntinghe-Wagenaar, T. Jeroen N. Hiltermann
Translational Lung Cancer Research  
2025;
14
(2)
:328-333
.
Sunvozertinib: shining light on lung cancer’s exon 20 fight
Tetsuya Mitsudomi
Translational Lung Cancer Research  
2025;
14
(2)
:334-340
.

Original Article

Study of the radiologic and pathologic correlations for subsolid lung adenocarcinoma with the application of whole-mount sections (ECTOP1011)
Ting Ye, Xuxia Shen, Shengping Wang, Haoxuan Wu, Yue Wang, Hong Hu, Yang Zhang, Qingyuan Huang, Zezhou Wang, Yajia Gu, Yuan Li, Haiquan Chen
Translational Lung Cancer Research  
2025;
14
(2)
:341-352
.
Rapid detection of non-small cell lung cancer driver mutations using droplet digital polymerase chain reaction analysis of bronchial washings: a prospective multicenter study
Kohei Somekawa, Nobuaki Kobayashi, Satoshi Nagaoka, Kenichi Seki, Yukihito Kajita, Suguru Muraoka, Ami Izawa, Ayami Kaneko, Yukiko Otsu, Momo Hirata, Sousuke Kubo, Ryo Nagasawa, Kota Murohashi, Hiroaki Fuji, Shuhei Teranishi, Ken Tashiro, Keisuke Watanabe, Nobuyuki Horita, Yu Hara, Makoto Kudo, Takeshi Kaneko
Translational Lung Cancer Research  
2025;
14
(2)
:353-362
.
Comparison of metastasis and treatment patterns among different histopathologic types of lung cancer: analysis of 6 years of nationwide lung cancer cohort data in Korea
Jeong Uk Lim, Kyu Yean Kim, Ho Cheol Kim, Tae-Jung Kim, Hong Kwan Kim, Mi Hyoung Moon, Kyongmin Sarah Beck, Yang Gun Suh, Chang Hoon Song, Jin Seok Ahn, Jeong Eun Lee, Jae Hyun Jeon, Chi Young Jung, Jeong Su Cho, Yoo Duk Choi, Seung Sik Hwang, Young Sik Park, Soon Ho Yoon, Joon Young Choi, Chang-Min Choi, Seung Hun Jang; Korean Association for Lung Cancer; Korea Central Cancer Registry
Translational Lung Cancer Research  
2025;
14
(2)
:363-384
.
Dual-layer spectral detector computed tomography multiparameter machine learning model for prediction of invasive lung adenocarcinoma
Jiayu Wan, Xue Lin, Zhaokai Wang, Peng Sun, Shen Gui, Tianhe Ye, Qianqian Fan, Weiwei Liu, Feng Pan, Bo Yang, Xiaotong Geng, Zhen Quan, Lian Yang
Translational Lung Cancer Research  
2025;
14
(2)
:385-397
.
Predictive value of perioperative carcinoembryonic antigen changes for recurrence in non-small cell lung cancer
Hua Sun, Sikai Wu, Zhongxiao Chen, Hao Liu, William C. Cho, Pasan Witharana, Minhua Ye, Dehua Ma, Chunguo Wang, Chengchu Zhu, Jianfei Shen
Translational Lung Cancer Research  
2025;
14
(2)
:398-407
.
Sleeve lobectomy versus lobectomy after neoadjuvant chemo-immunotherapy for non-small cell lung cancer invading the lobar bronchial orifice: a multicenter retrospective cohort study
Tianyue Ma, Jun Yi, Yong Ge, Haitang Yang, Jiayi Wang, Shuyuan Li, Ran Ma, Guodong Zhang, Hao Peng, Pingping Song, Feng Yao, Hao Zhang
Translational Lung Cancer Research  
2025;
14
(2)
:408-421
.
Immunotherapy efficacy between exon 19 deletion and exon 21 L858R mutation in advanced EGFR mutant non-small-cell lung cancer: a direct and indirect meta-analysis
Zihong Chen, Lanlan Pang, Yuwen Yang, Xinyi He, Jianhua Zhan, Lin Zhang, Kangqiao Xiong, Wenfeng Fang, Li Zhang, Yaxiong Zhang
Translational Lung Cancer Research  
2025;
14
(2)
:422-430
.
Spectral dual-layer detector CT-based radiomics-deep learning for predicting pathological aggressiveness of stage I lung adenocarcinoma: discrimination of precursor glandular lesions and invasive adenocarcinomas
Tong Wang, Zheng Fan, Yong Yue, Xiaomei Lu, Xiaoxu Deng, Yang Hou
Translational Lung Cancer Research  
2025;
14
(2)
:431-448
.
Whole-section digital analysis of immune profiles in surgically resected small cell lung carcinoma and their associations with molecular subtypes
Yanli Zhu, Jianghua Wu, Haiyue Wang, Kaiwen Chi, Xinting Diao, Minglei Zhuo, Dongmei Lin
Translational Lung Cancer Research  
2025;
14
(2)
:449-466
.
Real-world comparison of neoadjuvant pembrolizumab plus chemotherapy versus tislelizumab plus chemotherapy in patients with resectable non-small cell lung cancer: a retrospective cohort study of treatment outcomes
Yan Hu, Siying Ren, Juan Feng, Chao Zeng, Lulu Yang, Jinyou Liu, Fang Wu, Wenliang Liu
Translational Lung Cancer Research  
2025;
14
(2)
:467-479
.
Dual-phase computed tomography imaging for lung function assessment in patients with early-stage non-small cell lung cancer
Yizhen Jia, Qinmin Hao, Fen Wang, Jun Wang, Liang Chen, Mei Yuan
Translational Lung Cancer Research  
2025;
14
(2)
:480-490
.
Aspirin impedes non-small cell lung cancer development via fine-tuning the CD36 localization regulated by GPIHBP1
Wei Liu, Dujuan Qiao, Jia Chen, Ya Gao, Katsuhiro Okuda, Yoshihisa Shimada, Linong Yao
Translational Lung Cancer Research  
2025;
14
(2)
:491-512
.
Clinical application of three-dimensional reconstruction in anatomical analysis of the right anterior, lateral, and posterior basal segments (RS8, RS9, and RS10) for RS9 segmentectomy
Jiafu Zhu, Sui Chen, Yukang Lin, Jiangshan Huang, Marcus Taylor, Junji Ichinose, Yeon Wook Kim, Zihao Zheng, Jinyang Shi, Litao Yang, Jiangbo Lin
Translational Lung Cancer Research  
2025;
14
(2)
:513-525
.
Clinical-genomic nomogram for predicting sensitivity to second-line immunotherapy for advanced non-small cell lung cancer
Ying Hua, Ai Wang, Chao Xie, Apostolos C. Agrafiotis, Pinlang Zhang, Baosheng Li
Translational Lung Cancer Research  
2025;
14
(2)
:526-537
.
Efficacy of neoadjuvant immunochemotherapy in the treatment of stage III non-small-cell lung cancer with cancer driver gene mutations
Yuhong Yang, Jiacong Liu, Linhai Zhu, Xuhua Huang, Jiayue Ye, Nagashree Seetharamu, Hiroyuki Adachi, Jinming Xu, Yiqing Wang, Pinghui Xia, Wang Lv, Chong Zhang, Jian Hu
Translational Lung Cancer Research  
2025;
14
(2)
:538-551
.
Risk factors for postoperative pulmonary complications in non-adenocarcinoma non-small cell lung cancer patients undergoing surgery after neoadjuvant therapy
Hu Zhang, Xiaowei Mao, Jingwei Xu, Lijiang Song, Zhengwei Huang, Yao Li, Jiajing Sun, Jiali Qian, Shan Xu, Fabrizio Minervini, Kentaro Inamura, Zhengfu He
Translational Lung Cancer Research  
2025;
14
(2)
:552-562
.
Comparative outcomes of first-line PD-1/PD-L1 inhibitors plus chemotherapy for advanced squamous non-small cell lung cancer: a systematic review and network meta-analysis of randomized clinical trials
Zhefeng Liu, Zhikuan Wang, Jun Zhu, Haitao Tao, Ziwei Huang, Lu Han, Akshay J. Patel, Yi Hu
Translational Lung Cancer Research  
2025;
14
(2)
:563-574
.

Review Article

Lung cancer organoids: a new strategy for precision medicine research
Yuan Meng, Xinyi Shu, Jie Yang, Yangyueying Liang, Meiying Zhu, Xuerui Wang, Yue Li, Fanming Kong
Translational Lung Cancer Research  
2025;
14
(2)
:575-590
.
Radiotherapy as salvage therapy and an adjunct to immunotherapy: exploring local and abscopal mechanisms to overcome immunotherapy resistance: a narrative review
Yunxin Yang, Tong Liu, Song Mi, Xin Liu, Salma K. Jabbour, Ning Liang, Guodong Deng, Pingping Hu, Jiandong Zhang
Translational Lung Cancer Research  
2025;
14
(2)
:591-606
.

Case Report | iMDT Corner

Cerebrospinal fluid cytology for the diagnosis of lung cancer brain metastasis: a case report
Lidan Xing, Jiajia Liu, Haiyang Yan, Jing Chen, Lingling Gao, Muhammad Zubair Afzal, Toyoaki Hida, Shuai Zhao, Jingna Sun
Translational Lung Cancer Research  
2025;
14
(2)
:607-613
.

Case Report

Pathologic complete response following salvage surgery after lazertinib treatment in advanced EGFR-mutated lung adenocarcinoma: case report and literature review
Chanmi Kim, Jongsoo Park, Jang Hoon Lee, Seong Yong Jeong, June Hong Ahn
Translational Lung Cancer Research  
2025;
14
(2)
:614-618
.
Ion robotic bronchoscopy laser ablation and Da Vinci robotic segmentectomy for bilateral pulmonary nodules: a case report
Teng Sun, Yong Ge, Zhiqiao Chen, Tianyue Ma, Shoujie Feng, Hao Zhang
Translational Lung Cancer Research  
2025;
14
(2)
:619-624
.
Novel LZTR1 germline mutation as a mechanism of resistance to osimertinib in EGFR-mutated lung adenocarcinoma: a case report
Wai Park, Jeremy Fricke, Isa Mambetsariev, Giovanny Velasquez, Reza Nadaf-Rahrov, Shaira Therese Dingal, Pauline Kim, Razmig Babikian, Arya Amini, Michelle Afkhami, Ravi Salgia
Translational Lung Cancer Research  
2025;
14
(2)
:625-630
.
Partial response to lorlatinib in thoracic inflammatory myofibroblastic tumor harboring complex and rare ALK fusions: a case report
Li-Bo Tang, Ying-Long Peng, Xiao-Rong Yang, Jia-Ting Li, Chang Lu, Mei-Mei Zheng, Lu Sun, Zheng Yang, Li-Xu Yan, Yu Deng, Zhi-Hong Chen, Si-Di Lv, Qing Zhou, Chong-Rui Xu
Translational Lung Cancer Research  
2025;
14
(2)
:631-638
.
Unravelling the complexity of EGFR-mutated lung adenocarcinoma: a unique case report with histological transformations and co-alteration acquisition
Anissa Boutahir, Véronique Dalstein, Jean Baptiste Oudart, Gaëtan Deslee, Chistine Clavel, Maxime Dewolf, Anne Durlach, Julien Ancel
Translational Lung Cancer Research  
2025;
14
(2)
:639-648
.

Letter to the Editor

Learning from chronic disease screening success: developing efficient, convenient, and affordable lung cancer screening methods to achieve universal coverage
Jianxing He, Wenhua Liang, Nanshan Zhong
Translational Lung Cancer Research  
2025;
14
(2)
:649-651
.

Erratum

Erratum: Tumor cavitation in patients with non-small-cell lung cancer receiving anti-angiogenic therapy with apatinib
Editorial Office
Translational Lung Cancer Research  
2025;
14
(2)
:652
.