Vol 8, No 4 (August 31, 2019) - Translational Lung Cancer Research

Editorial

Lung cavitation in lung metastases of gastric and non-small-cell lung cancer patients treated with apatinib

Fabiana Letizia Cecere, Andres Aguilar, Rafael Rosell

PDF Pages: 317-318 Full Text (1885) Open Access

Influence and mechanism of lung cavitation development on antiangiogenic therapy: is cavitation the new caveat?

Lorenzo Calvetti, Giuseppe Aprile

PDF Pages: 319-322 Full Text (3735) Open Access

Original Article

Presence of intra-tumoral CD61+ megakaryocytes predicts poor prognosis in non-small cell lung cancer

Weizhe Huang, Shen Zhao, Wei Xu, Zhikui Zhang, Xiangdong Ding, Jianxing He, Wenhua Liang

PDF Pages: 323-331 Full Text (5004) Open Access

Prospective assessment of demographic characteristics associated with worse health related quality of life measures following definitive chemoradiation in patients with locally advanced non-small cell lung cancer

Jennifer Vogel, Xingmei Wang, Andrea B. Troxel, Charles B. Simone II, Ramesh Rengan, Lilie L. Lin

PDF Pages: 332-339 Full Text (1769) Open Access

Hsp90 inhibitors enhance the antitumoral effect of osimertinib in parental and osimertinib-resistant non-small cell lung cancer cell lines

Jordi Codony-Servat, Santiago Viteri, Carles Codony-Servat, Masaoki Ito, Jillian Willhelmina Paulina Bracht, Jordi Berenguer, Imane Chaib, Miguel Angel Molina-Vila, Niki Karachaliou, Rafael Rosell

PDF Pages: 340-351 Full Text (2637) Open Access

OX40 and OX40L protein expression of tumor infiltrating lymphocytes in non-small cell lung cancer and its role in clinical outcome and relationships with other immune biomarkers

Yayi He, Xiaoshen Zhang, Keyi Jia, Rafal Dziadziuszko, Sha Zhao, Juan Deng, Hao Wang, Fred R. Hirsch, Caicun Zhou

PDF Pages: 352-366 Full Text (4921) Open Access

Incidence, prognostic factors, and a nomogram of lung cancer with bone metastasis at initial diagnosis: a population-based study

Xuan-Qi Zheng, Jin-Feng Huang, Jia-Liang Lin, Liang Chen, Ting-Ting Zhou, Dong Chen, Dong-Dong Lin, Jian-Fei Shen, Ai-Min Wu

PDF Pages: 367-379 Full Text (2966) Open Access

Exploring barriers to lung cancer patient access, diagnosis, referral and treatment in Kwazulu-Natal, South Africa: the health providers’ perspectives

Buhle Lubuzo, Themba Ginindza, Khumbulani Hlongwana

PDF Pages: 380-391 Full Text (4210) Open Access

Liquid biopsies using pleural effusion-derived exosomal DNA in advanced lung adenocarcinoma

Zhengbo Song, Zhijian Cai, Junrong Yan, Yang W. Shao, Yiping Zhang

PDF Pages: 392-400 Full Text (2381) Open Access

Quantitative features of dual-energy spectral computed tomography for solid lung adenocarcinoma with EGFR and KRAS mutations, and ALK rearrangement: a preliminary study

Meng Li, Li Zhang, Wei Tang, Pei-Qing Ma, Li-Na Zhou, Yu-Jing Jin, Lin-Lin Qi, Ning Wu

PDF Pages: 401-412 Full Text (2676) Open Access

The association of PD-L1 expression with the efficacy of anti- PD-1/PD-L1 immunotherapy and survival of non-small cell lung cancer patients: a meta-analysis of randomized controlled trials

Yangyang Xu, Bing Wan, Xi Chen, Ping Zhan, Yuan Zhao, Tianli Zhang, Hongbing Liu, Muhammad Zubair Afzal, Said Dermime, Steven N. Hochwald, Paul Hofman, Hossein Borghaei, Dang Lin, Tangfeng Lv, Yong Song, written on behalf of AME Lung Cancer Collaborative Group

PDF Pages: 413-428 Full Text (12965) Open Access

The clinicopathological and prognostic significance of PD-L1 expression assessed by immunohistochemistry in lung cancer: a meta-analysis of 50 studies with 11,383 patients

Huijuan Li, Yangyang Xu, Bing Wan, Yong Song, Ping Zhan, Yangbo Hu, Qun Zhang, Fang Zhang, Hongbing Liu, Tianhong Li, Haruhiko Sugimura, Federico Cappuzzo, Dang Lin, Tangfeng Lv, written on behalf of AME Lung Cancer Collaborative Group

PDF Pages: 429-449 Full Text (4787) Open Access

Retrospective analysis of docetaxel in combination with ramucirumab for previously treated non-small cell lung cancer patients

Akihiro Yoshimura, Tadaaki Yamada, Yusuke Okuma, Rui Kitadai, Takayuki Takeda, Takanori Kanematsu, Hisatsugu Goto, Hiroto Yoneda, Taishi Harada, Yutaka Kubota, Takahiro Yamada, Koji Date, Shinsuke Shiotsu, Kazuhiro Nagata, Yusuke Chihara, Yoshiko Kaneko, Junji Uchino, Yasuhiko Nishioka, Koichi Takayama

PDF Pages: 450-460 Full Text (3510) Open Access

Lung cancer in Spain: information from the Thoracic Tumors Registry (TTR study)

Mariano Provencio, Enric Carcereny, Delvys Rodríguez-Abreu, Rafael López-Castro, María Guirado, Carlos Camps, Joaquim Bosch-Barrera, Rosario García-Campelo, Ana Laura Ortega-Granados, José Luis González-Larriba, Joaquín Casal-Rubio, Manuel Domine, Bartomeu Massutí, María Ángeles Sala, Reyes Bernabé, Juana Oramas, Elvira del Barco

PDF Pages: 461-475 Full Text (4887) Open Access

MUC16 in non-small cell lung cancer patients affected by familial lung cancer and indoor air pollution: clinical characteristics and cell behaviors

Ying Chen, Yunchao Huang, Madiha Kanwal, Guangjian Li, Jiapeng Yang, Huatao Niu, Zhenhui Li, Xiaojie Ding

PDF Pages: 476-488 Full Text (3997) Open Access

Metabolic profiles of serum samples from ground glass opacity represent potential diagnostic biomarkers for lung cancer

Jian-Zhong Li, Yuan-Yang Lai, Jian-Yong Sun, Li-Na Guan, Hong-Fei Zhang, Chen Yang, Yue-Feng Ma, Tao Liu, Wen Zhao, Xiao-Long Yan, Shao-Min Li

PDF Pages: 489-499 Full Text (2065) Open Access

Influence and mechanism of lung cavitation development on antiangiogenic therapy

Man Jiang, Chuantao Zhang, Dong Liu, Yongjie Wang, Hongmei Wang, Tianjun Li, Helei Hou, Na Zhou, Jingjuan Zhu, Hongying Lv, Chuanyu Zhang, Bingliang Fang, Xiaochun Zhang

PDF Pages: 500-512 Full Text (2213) Open Access

Brief Report

Sensitive molecular testing methods can demonstrate NSCLC driver mutations in malignant pleural effusion despite non-malignant cytology

Daniel P. Steinfort, Sevastjan Kranz, Anthony Dowers, Leakhena Leas, Voula Dimitriadis, Kym Pham, Arthur Hsu, Steven Bozinovski, Louis B. Irving, Paula Loveland, Michael Christie

PDF Pages: 513-518 Full Text (1716) Open Access

Study Protocol

Rationale and design of a phase II study to evaluate prophylactic treatment of dacomitinib-induced dermatologic adverse events in epidermal growth factor receptor-mutated advanced non-small cell lung cancer (SPIRAL-Daco study)

Masahiro Iwasaku, Junji Uchino, Tadaaki Yamada, Yusuke Chihara, Takayuki Shimamoto, Nobuyo Tamiya, Yoshiko Kaneko, Fumiaki Kiyomi, Koichi Takayama

PDF Pages: 519-523 Full Text (1869) Open Access

Review Article

Treatment modes for EGFR mutations in patients with brain metastases from non-small cell lung cancer: controversy, causes, and solutions

Hongqing Zhuang, Siyu Shi, Joe Y. Chang

PDF Pages: 524-531 Full Text (1753) Open Access

Case Report

Effective targeted therapy based on dynamic monitoring of gene mutations in non-small cell lung cancer

Tan Deng, Jiao Tang, Lijun Zhou, Huaxin Duan

PDF Pages: 532-538 Full Text (1842) Open Access

News

The first attempt worldwide to test PD-1 antibody on multiple “Stage 0” lung cancer

Editorial Office

PDF Pages: 556-557 Full Text (1108) Open Access

Erratum

Erratum: Precision radiotherapy for patients with locally advanced non-small cell lung cancer in the era of immunotherapy and precision medicine

Editorial Team

PDF Pages: 558 Full Text (898) Open Access

Vol 8, No 4 (August 31, 2019): Translational Lung Cancer Research