Vol 8, No 5 (October 29, 2019): Translational Lung Cancer Research

Original Article

Does selected immunological panel possess the value of predicting the prognosis of early-stage resectable non-small cell lung cancer?
Xiaoshen Zhang, Yayi He, Keyi Jia, Rafal Dziadziuszko, Sha Zhao, Juan Deng, Hao Wang, Fred R. Hirsch, Caicun Zhou
Translational Lung Cancer Research  
2019;
8
(5)
:559-574
.
The impact of previous therapy strategy on the efficiency of anlotinib hydrochloride as a third-line treatment on patients with advanced non-small cell lung cancer (NSCLC): a subgroup analysis of ALTER0303 trial
Lili Wang, Zhen He, Sen Yang, Hong Tang, Yufeng Wu, Shaomei Li, Baohui Han, Kai Li, Li Zhang, Jianhua Shi, Zhehai Wang, Ying Cheng, Jianxing He, Yuankai Shi, Weiqiang Chen, Yi Luo, Lin Wu, Xiuwen Wang, Kejun Nan, Faguang Jin, Jian Dong, Baolan Li, Yan Sun, Qiming Wang
Translational Lung Cancer Research  
2019;
8
(5)
:575-583
.
EGFR T790M detection rate in lung adenocarcinomas at baseline using droplet digital PCR and validation by ultra-deep next generation sequencing
Lucio Lettig, Nora Sahnane, Francesco Pepe, Roberta Cerutti, Chiara Albeni, Francesca Franzi, Giovanni Veronesi, Francesca Ogliari, Alessia Pastore, Alessandro Tuzi, Graziella Pinotti, Antonella Bovio, Claudio Verusio, Monica Giordano, Giancarlo Troncone, Fausto Sessa, Umberto Malapelle, Daniela Furlan
Translational Lung Cancer Research  
2019;
8
(5)
:584-592
.
Survival score to characterize prognosis in inoperable stage III NSCLC after chemoradiotherapy
Julian Taugner, Lukas Käsmann, Chukwuka Eze, Maurice Dantes, Olarn Roengvoraphoj, Kathrin Gennen, Monika Karin, Oleg Petruknov, Amanda Tufman, Claus Belka, Farkhad Manapov
Translational Lung Cancer Research  
2019;
8
(5)
:593-604
.
Comparison of Veterans Affairs, Mayo, Brock classification models and radiologist diagnosis for classifying the malignancy of pulmonary nodules in Chinese clinical population
Xiaonan Cui, Marjolein A. Heuvelmans, Daiwei Han, Yingru Zhao, Shuxuan Fan, Sunyi Zheng, Grigory Sidorenkov, Harry J. M. Groen, Monique D. Dorrius, Matthijs Oudkerk, Geertruida H. de Bock, Rozemarijn Vliegenthart, Zhaoxiang Ye
Translational Lung Cancer Research  
2019;
8
(5)
:605-613
.
Systematic analysis identifies three-lncRNA signature as a potentially prognostic biomarker for lung squamous cell carcinoma using bioinformatics strategy
Jing Hu, Lutong Xu, Tao Shou, Qiang Chen
Translational Lung Cancer Research  
2019;
8
(5)
:614-635
.
Validation of a serum 4-microRNA signature for the detection of lung cancer
Xia Yang, Wenmei Su, Xiuyuan Chen, Qianqian Geng, Jingyi Zhai, Hu Shan, Chunfang Guo, Zhuwen Wang, Han Fu, Hui Jiang, Jules Lin, Kiran Hari Lagisetty, Jie Zhang, Yali Li, Shuanying Yang, Pierre P. Massion, David G. Beer, Andrew C. Chang, Nithya Ramnath, Guoan Chen
Translational Lung Cancer Research  
2019;
8
(5)
:636-648
.
Synchronous multiple lung cancers presenting as multifocal pure ground glass nodules: are whole-body positron emission tomography/computed tomography and brain enhanced magnetic resonance imaging necessary?
Meng Li, Yuan Wan, Li Zhang, Li-Na Zhou, Zhuo Shi, Rui Zhang, Yan-Lei Hou, Ning Wu
Translational Lung Cancer Research  
2019;
8
(5)
:649-657
.
Management of the inter-segmental plane using the “Combined Dimensional Reduction Method” is safe and viable in uniport video-assisted thoracoscopic pulmonary segmentectomy
Bin Zheng, Guobing Xu, Xiayu Fu, Weidong Wu, Mingqiang Liang, Taidui Zeng, Shuliang Zhang, Yong Zhu, Wei Zheng, Chun Chen, Benoît Bédat, Scott J. Swanson, Terumoto Koike, Hisashi Iwata, Benedetta Bedetti, Masaaki Sato, written on behalf of the AME Thoracic Surgery Collaborative Group
Translational Lung Cancer Research  
2019;
8
(5)
:658-666
.
Targeting PKCι-PAK1 in EGFR-mutation positive non-small cell lung cancer
Masaoki Ito, Carles Codony-Servat, Niki Karachaliou, Rafael Rosell
Translational Lung Cancer Research  
2019;
8
(5)
:667-673
.
Prognostic roles of the expression of sphingosine-1-phosphate metabolism enzymes in non-small cell lung cancer
Yingqin Wang, Yaxing Shen, Xia Sun, Tinah L. Hong, Long Shuang Huang, Ming Zhong
Translational Lung Cancer Research  
2019;
8
(5)
:674-681
.
Brain metastases from lung cancer with neuropsychiatric symptoms as the first symptoms
Kai Dong, Lei Liu, Zhipeng Yu, Di Wu, Qian Zhang, Xiaoqin Huang, Jianping Ding, Haiqing Song
Translational Lung Cancer Research  
2019;
8
(5)
:682-691
.

Review Article

Current perspectives on statins as potential anti-cancer therapeutics: clinical outcomes and underlying molecular mechanisms
Ali Fatehi Hassanabad
Translational Lung Cancer Research  
2019;
8
(5)
:692-699
.

Case Report

Primary pleural epithelioid sarcoma of the proximal type: a diagnostic and therapeutic challenge
Zeeshan Ahmad, Qasim Stanazai, Staphanie Wright, Matthew Smolkin, Patrick C. Ma
Translational Lung Cancer Research  
2019;
8
(5)
:700-705
.

Editorial Commentary

KEYNOTE-021 cohorts D and H suggest modest benefit in combining ipilimumab with pembrolizumab in second-line or later advanced non-small cell lung cancer treatment
Amy Lauren Cummings, Kate M. Santoso, Jonathan W. Goldman
Translational Lung Cancer Research  
2019;
8
(5)
:706-709
.
Immunotherapy in EGFR mutant non-small cell lung cancer: when, who and how?
Debora Bruno, Afshin Dowlati
Translational Lung Cancer Research  
2019;
8
(5)
:710-714
.
Can PD-L1 tumor proportion score be used as the key to unlocking the KEYNOTE studies of pembrolizumab in advanced lung cancer?
Andrew J. Piper, Kartik Sehgal, Daniel B. Costa, Deepa Rangachari
Translational Lung Cancer Research  
2019;
8
(5)
:715-722
.
KEYNOTE-042: is lowering the PD-L1 threshold for first-line pembrolizumab monotherapy a good idea?
Jose M. Pacheco
Translational Lung Cancer Research  
2019;
8
(5)
:723-727
.
First-line immunotherapy for patients with advanced stage or metastatic non-small cell lung cancer…finally what threshold of PD-L1 expression on tumor cells?
Paul Hofman
Translational Lung Cancer Research  
2019;
8
(5)
:728-730
.
The KEY to the end of the chemotherapy in advanced non-small cell lung cancer, or not yet?
Yiqing Huang, Robert J. Walsh, Ross A. Soo
Translational Lung Cancer Research  
2019;
8
(5)
:731-737
.