Most Read article list (ranking real-time pageviews since the publication of the article)

Wenhua Liang, Kaican Cai, Chun Chen, Haiquan Chen, Qixun Chen, Junke Fu, Jian Hu, Tao Jiang, Wenjie Jiao, Shuben Li, Changhong Liu, Deruo Liu, Wei Liu, Yang Liu, Haitao Ma, Xiaojie Pan, Guibin Qiao, Hui Tian, Li Wei, Yi Zhang, Song Zhao, Xiaojing Zhao, Chengzhi Zhou, Yuming Zhu, Ran Zhong, Feng Li, Rafael Rosell, Mariano Provencio, Erminia Massarelli, Mara B. Antonoff, Toyoaki Hida, Marc de Perrot, Steven H. Lin, Massimo Di Maio, Antonio Rossi, Dirk De Ruysscher, Robert A. Ramirez, Wolfram C. M. Dempke, D. Ross Camidge, Nicolas Guibert, Raffaele Califano, Qi Wang, Shengxiang Ren, Caicun Zhou, Jianxing He

Published online: 31 December 2020

PDF Pages: 2696-2715 Full Text (17317) COI Form Open Access

Review Article

The role of the immune system in non-small cell lung carcinoma and potential for therapeutic intervention

Joanna Domagala-Kulawik

Published online: 19 April 2015

PDF Pages: 177-190 Full Text (17286) Open Access

Original Article

Brain metastases from lung cancer with neuropsychiatric symptoms as the first symptoms

Kai Dong, Lei Liu, Zhipeng Yu, Di Wu, Qian Zhang, Xiaoqin Huang, Jianping Ding, Haiqing Song

Published online: 29 October 2019

PDF Pages: 682-691 Full Text (16977) Open Access

Evidence-Based Medicine

Prognostic value of circulating endothelial cells in non-small cell lung cancer patients: a systematic review and meta-analysis

Yafang Liu, Dongmei Yuan, Wei Ye, Tangfeng Lv, Yong Song

Published online: 28 October 2015

PDF Pages: 610-618 Full Text (16781) Open Access

Review Articles

Role of HGF/MET axis in resistance of lung cancer to contemporary management

Kanwal Pratap Singh Raghav, Ana Maria Gonzalez-Angulo, George R. Blumenschein Jr

Published online: 27 September 2012

PDF Pages: 179-193 Full Text (16719) Open Access

Review Article on Update on Pathology and Predictive Biomarkers of Lung Cancer

Classification of pulmonary neuroendocrine tumors: new insights

Giuseppe Pelosi, Angelica Sonzogni, Sergio Harari, Adriana Albini, Enrica Bresaola, Caterina Marchiò, Federica Massa, Luisella Righi, Gaia Gatti, Nikolaos Papanikolaou, Namrata Vijayvergia, Fiorella Calabrese, Mauro Papotti

Published online: 11 October 2017

PDF Pages: 513-529 Full Text (16414) Open Access

Editorial Commentary

The natural course of incidentally detected, small, subsolid lung nodules—is follow-up needed beyond current guideline recommendations?

Benedikt H. Heidinger, Mario Silva, Constance de Margerie-Mellon, Paul A. VanderLaan, Alexander A. Bankier

Published online: 31 December 2019

PDF Pages: S412-S417 Full Text (16408) Open Access

Review Article

Application of immunohistochemistry in diagnosis and management of malignant mesothelioma

David B. Chapel, Jefree J. Schulte, Aliya N. Husain, Thomas Krausz

Published online: 28 February 2020

PDF Pages: S3-S27 Full Text (16167) Open Access

Review Article

PiggyBac transposon vectors: the tools of the human gene encoding

Shuang Zhao, Enze Jiang, Shuangshuang Chen, Yuan Gu, Anna Junjie Shangguan, Tangfeng Lv, Liguo Luo, Zhenghong Yu

Published online: 02 February 2016

PDF Pages: 120-125 Full Text (15901) Open Access

Review Articles

From tissue to molecular phenotyping: Pre-analytical requirements

Thomas R. Muley, Felix JF. Herth, Philipp A. Schnabel, Hendrik Dienemann, Michael Meister

Published online: 30 June 2012

PDF Pages: 111-121 Full Text (15840) Open Access

Original Article

Ratio of maximum standardized uptake value to primary tumor size is a prognostic factor in patients with advanced non-small cell lung cancer

Fangfang Chen, Yanwen Yao, Chunyan Ma, Xingqun Ma, Zhaofeng Wang, Tangfeng Lv, Xinwu Xiao, Jie Yin, Yong Song

Published online: 24 February 2015

PDF Pages: 18-26 Full Text (15825) Open Access

Review Article

Diagnostic and prognostic biomarkers for malignant mesothelioma: an update

Zhongjian Chen, Giovanni Gaudino, Harvey I. Pass, Michele Carbone, Haining Yang

Published online: 29 June 2017

PDF Pages: 259-269 Full Text (15602) Open Access

Controversies on Lung Cancer: Pros and Cons (Section Chairs: Suresh Senan, Helmut H. Popper)

Pros: Can tissue biopsy be replaced by liquid biopsy?

Marius Ilié, Paul Hofman

Published online: 29 August 2016

PDF Pages: 420-423 Full Text (15603) Open Access

Perspectives

Functional CT imaging techniques for the assessment of angiogenesis in lung cancer

Thomas Henzler, Jingyun Shi, Hashim Jafarov, Stefan O. Schoenberg, Christian Manegold, Christian Fink, Gerald Schmid-Bindert

Published online: 18 February 2012

PDF Pages: 78-83 Full Text (15331) Open Access

Review Article

BAP1, a tumor suppressor gene driving malignant mesothelioma

Mitchell Cheung, Joseph R. Testa

Published online: 29 June 2017

PDF Pages: 270-278 Full Text (15241) Open Access

Review Article on Small Cell Lung Cancer

Cellular and molecular biology of small cell lung cancer: an overview

Niki Karachaliou, Sara Pilotto, Chiara Lazzari, Emilio Bria, Filippo de Marinis, Rafael Rosell

Published online: 02 February 2016

PDF Pages: 2-15 Full Text (15075) Open Access

Review Article

Targeting ferroptosis for cancer therapy: exploring novel strategies from its mechanisms and role in cancers

Minlin Jiang, Meng Qiao, Chuanliang Zhao, Juan Deng, Xuefei Li, Caicun Zhou

Published online: 28 August 2020

PDF Pages: 1569-1584 Full Text (14950) Peer Review File COI Form Open Access

Review Article

Histopathological transformation to small-cell lung carcinoma in non-small-cell lung carcinoma tumors

Rita Dorantes-Heredia, José Manuel Ruiz-Morales, Fernando Cano-García

Published online: 29 August 2016

PDF Pages: 401-412 Full Text (14848) Open Access

Original Article

Comparison of methods for circulating cell-free DNA isolation using blood from cancer patients: impact on biomarker testing

Clara Pérez-Barrios, Irene Nieto-Alcolado, María Torrente, Carolina Jiménez-Sánchez, Virginia Calvo, Lourdes Gutierrez-Sanz, Magda Palka, Encarnación Donoso-Navarro, Mariano Provencio, Atocha Romero

Published online: 29 December 2016

PDF Pages: 665-672 Full Text (14779) Open Access

Review Articles on Small Cell Lung Cancer: New Models, Markers and Beyond

Current standards for clinical management of small cell lung cancer

Anna F. Farago, Florence K. Keane

Published online: 15 February 2018

PDF Pages: 69-79 Full Text (14624) Open Access

Editorial Commentary

Optimal management of pulmonary ground-glass opacity nodules

Yeon Wook Kim, Choon-Taek Lee

Published online: 31 December 2019

PDF Pages: S418-S424 Full Text (14683) Open Access

Review Article

ALK and crizotinib: after the honeymoon…what else? Resistance mechanisms and new therapies to overcome it

Christian Rolfo, Francesco Passiglia, Marta Castiglia, Luis E. Raez, Paul Germonpre, Ignacio Gil-Bazo, Karen Zwaenepoel, Annemieke De Wilde, Giuseppe Bronte, Antonio Russo, Jan P. Van Meerbeeck, Paul Van Schil, Patrick Pauwels

Published online: 28 August 2014

PDF Pages: 250-261 Full Text (14522) Open Access

Review Article

Phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin (PI3K-Akt-mTOR) signaling pathway in non-small cell lung cancer

Po Yee Yip

Published online: 19 April 2015

PDF Pages: 165-176 Full Text (14527) Open Access

Original Article on Small Cell Lung Cancer: New Models, Markers and Beyond

Small cell lung cancer tumors and preclinical models display heterogeneity of neuroendocrine phenotypes

Wei Zhang, Luc Girard, Yu-An Zhang, Tomohiro Haruki, Mahboubeh Papari-Zareei, Victor Stastny, Hans K. Ghayee, Karel Pacak, Trudy G. Oliver, John D. Minna, Adi F. Gazdar

Published online: 15 February 2018

PDF Pages: 32-49 Full Text (14320) Open Access

Original Article

The association of PD-L1 expression with the efficacy of anti- PD-1/PD-L1 immunotherapy and survival of non-small cell lung cancer patients: a meta-analysis of randomized controlled trials

Yangyang Xu, Bing Wan, Xi Chen, Ping Zhan, Yuan Zhao, Tianli Zhang, Hongbing Liu, Muhammad Zubair Afzal, Said Dermime, Steven N. Hochwald, Paul Hofman, Hossein Borghaei, Dang Lin, Tangfeng Lv, Yong Song, written on behalf of AME Lung Cancer Collaborative Group

Published online: 31 August 2019

PDF Pages: 413-428 Full Text (14381) Open Access

Consensus

International consensus on severe lung cancer—the first edition

Chengzhi Zhou, Shiyue Li, Jun Liu, Qian Chu, Liyun Miao, Linbo Cai, Xiuyu Cai, Yu Chen, Fei Cui, Yuchao Dong, Wen Dong, Wenfeng Fang, Yong He, Weifeng Li, Min Li, Wenhua Liang, Gen Lin, Jie Lin, Xinqing Lin, Hongbing Liu, Ming Liu, Xinlin Mu, Yi Hu, Jie Hu, Yang Jin, Ziming Li, Yinyin Qin, Shengxiang Ren, Gengyun Sun, Yihong Shen, Chunxia Su, Kejing Tang, Lin Wu, Mengzhao Wang, Huijuan Wang, Kai Wang, Yuehong Wang, Ping Wang, Hongmei Wang, Qi Wang, Zhijie Wang, Xiaohong Xie, Zhanhong Xie, Xin Xu, Fei Xu, Meng Yang, Boyan Yang, Xiangjun Yi, Xiaoqun Ye, Feng Ye, Zongyang Yu, Dongsheng Yue, Bicheng Zhang, Jian Zhang, Jianqing Zhang, Xiaoju Zhang, Wei Zhang, Wei Zhao, Bo Zhu, Zhengfei Zhu, Wenzhao Zhong, Chunxue Bai, Liangan Chen, Baohui Han, Chengping Hu, Shun Lu, Weimin Li, Yong Song, Jie Wang, Caicun Zhou, Jianying Zhou, Yanbin Zhou, Yuichi Saito, Yoshinobu Ichiki, Hitoshi Igai, Satoshi Watanabe, Sara Bravaccini, Alfonso Fiorelli, Francesco Petrella, Takeo Nakada, Piergiorgio Solli, Nikolaos Tsoukalas, Yuki Kataoka, Taichiro Goto, Rossana Berardi, Jianxing He, Nanshan Zhong

Published online: 29 June 2021

PDF Pages: 2633-2666 Full Text (14253) COI Form Open Access

Review Articles

Inhibition of insulin-like growth factor receptor: end of a targeted therapy?

Rathi N. Pillai, Suresh S. Ramalingam

Published online: 14 January 2013

PDF Pages: 14-22 Full Text (14115) Open Access

Review Article

Inherited lung cancer syndromes targeting never smokers

Hiromasa Yamamoto, Yasushi Yatabe, Shinichi Toyooka

Published online: 28 August 2018

PDF Pages: 498-504 Full Text (14160) Open Access

Review Article

Biology and clinical significance of circulating tumor cell subpopulations in lung cancer

Linda O’Flaherty, Harriet Wikman, Klaus Pantel

Published online: 24 August 2017

PDF Pages: 431-443 Full Text (13861) Open Access

Review Article on Small Cell Lung Cancer

Small cell lung cancer (SCLC): no treatment advances in recent years

Filippos Koinis, Athanasios Kotsakis, Vasileios Georgoulias

Published online: 02 February 2016

PDF Pages: 39-50 Full Text (13818) Open Access

Review Article

Prognostic markers in lung cancer: is it ready for prime time?

Chang-Qi Zhu, Ming-Sound Tsao

Published online: 29 June 2014

PDF Pages: 149-158 Full Text (13798) Open Access

Review Article

Lung cancer in females—sex-based differences from males in epidemiology, biology, and outcomes: a narrative review

Kaylan Gee, Sai Yendamuri

Published online: 29 January 2024

PDF Pages: 163-178 Full Text (13588) Reporting Checklist Peer Review File COI Form Open Access

Review Article

Methods of measurement for tumor mutational burden in tumor tissue

Bárbara Meléndez, Claude Van Campenhout, Sandrine Rorive, Myriam Remmelink, Isabelle Salmon, Nicky D’Haene

Published online: 01 December 2018

PDF Pages: 661-667 Full Text (13453) Open Access

Review Article

A narrative review of tumor-associated macrophages in lung cancer: regulation of macrophage polarization and therapeutic implications

Sahar Sadat Sedighzadeh, Amin Pastaki Khoshbin, Sepideh Razi, Mahsa Keshavarz-Fathi, Nima Rezaei

Published online: 29 April 2021

PDF Pages: 1889-1916 Full Text (13411) Reporting Checklist Peer Review File COI Form Open Access

Review Article

Concordance of IHC, FISH and RT-PCR for EML4-ALK rearrangements

Cristina Teixidó, Niki Karachaliou, Vicente Peg, Ana Gimenez-Capitan, Rafael Rosell

Published online: 15 April 2014

PDF Pages: 70-74 Full Text (13194) Open Access

Review Articles on Non-Small Cell Lung Cancer

Epigenetics in non-small cell lung cancer: from basics to therapeutics

Junaid Ansari, Rodney E. Shackelford, Hazem El-Osta

Published online: 28 April 2016

PDF Pages: 155-171 Full Text (12764) Open Access

Review Article on New Developments in Lung Cancer Diagnosis and Pathological Patient Management Strategies

A narrative review of digital pathology and artificial intelligence: focusing on lung cancer

Taro Sakamoto, Tomoi Furukawa, Kris Lami, Hoa Hoang Ngoc Pham, Wataru Uegami, Kishio Kuroda, Masataka Kawai, Hidenori Sakanashi, Lee Alex Donald Cooper, Andrey Bychkov, Junya Fukuoka

Published online: 28 October 2020

PDF Pages: 2255-2276 Full Text (12756) Reporting Checklist Peer Review File COI Form Open Access

Original Article

Characterization of the lung microbiome and exploration of potential bacterial biomarkers for lung cancer

Chen Cheng, Zhifeng Wang, Jingqiao Wang, Chao Ding, Chuang Sun, Pingli Liu, Xiaoqiang Xu, Yanan Liu, Bi Chen, Bing Gu

Published online: 29 June 2020

PDF Pages: 693-704 Full Text (12739) COI Form Open Access

Review Articles on Small Cell Lung Cancer: New Models, Markers and Beyond

Targeting DNA damage repair in small cell lung cancer and the biomarker landscape

Triparna Sen, Carl M. Gay, Lauren Averett Byers

Published online: 15 February 2018

PDF Pages: 50-68 Full Text (12602) Open Access

Consensus

International expert consensus on immunotherapy for early-stage non-small cell lung cancer

Wenhua Liang, Kaican Cai, Qingdong Cao, Chun Chen, Haiquan Chen, Jun Chen, Ke-Neng Chen, Qixun Chen, Tianqing Chu, Yuchao Dong, Jiang Fan, Wentao Fang, Junke Fu, Xiangning Fu, Shugeng Gao, Di Ge, Guojun Geng, Qing Geng, Jie He, Jian Hu, Jie Hu, Wei-Dong Hu, Feng Jiang, Tao Jiang, Wenjie Jiao, He-Cheng Li, Qiang Li, Shanqing Li, Shuben Li, Xiangnan Li, Yong-De Liao, Changhong Liu, Hongxu Liu, Yang Liu, Zhuming Lu, Qingquan Luo, Haitao Ma, Xiaojie Pan, Guibin Qiao, Shengxiang Ren, Weiyu Shen, Yong Song, Daqiang Sun, Guangsuo Wang, Jie Wang, Mengzhao Wang, Qiwen Wang, Wen-Xiang Wang, Li Wei, Ming Wu, Nan Wu, Hui Xia, Shi-Dong Xu, Fan Yang, Kang Yang, Yue Yang, Fenglei Yu, Zhen-Tao Yu, Dong-Sheng Yue, Lanjun Zhang, Weidong Zhang, Zhenfa Zhang, Guofang Zhao, Jian Zhao, Xiaojing Zhao, Chengzhi Zhou, Qinghua Zhou, Kunshou Zhu, Yuming Zhu, Toyoaki Hida, Wolfram C. M. Dempke, Antonio Rossi, Marc de Perrot, Robert A. Ramirez, Mariano Provencio, Jay M. Lee, Antonio Passaro, Lorenzo Spaggiari, Jonathan Spicer, Nicolas Girard, Patrick M. Forde, Tony S. K. Mok, Tina Cascone, Jianxing He; CATO consensus group

Published online: 30 September 2022

PDF Pages: 1742-1762 Full Text (12573) COI Form Open Access

Review Article

Blood-based tumor biomarkers in lung cancer for detection and treatment

Hirva Mamdani, Shahid Ahmed, Samantha Armstrong, Tony Mok, Shadia I. Jalal

Published online: 16 October 2017

PDF Pages: 648-660 Full Text (12403) Open Access

Review Articles

Non-neuronal cholinergic system in airways and lung cancer susceptibility

Laura Saracino, Michele Zorzetto, Simona Inghilleri, Ernesto Pozzi, Giulia Maria Stella

Published online: 17 August 2013

PDF Pages: 284-294 Full Text (12335) Open Access

Review Article

Tobacco and the lung cancer epidemic in China

Mark Parascandola, Lin Xiao

Published online: 30 May 2019

PDF Pages: S21-S30 Full Text (12243) Open Access

Review Article

Recent developments in limited stage small cell lung cancer

Kristin A. Higgins, Sophia Gorgens, Lisa J. Sudmeier, Corinne Faivre-Finn

Published online: 12 September 2019

PDF Pages: S147-S152 Full Text (12237) Open Access

Review Article

Lung cancer vaccines: current status and future prospects

Charmaine A. Ramlogan-Steel, Jason C. Steel, John C. Morris

Published online: 24 February 2014

PDF Pages: 46-52 Full Text (12224) Open Access

Systematic Review and Meta-analysis

Comparison between endobronchial ultrasound-guided transbronchial biopsy and CT-guided transthoracic lung biopsy for the diagnosis of peripheral lung cancer: a systematic review and meta-analysis

Ping Zhan, Qing-Qing Zhu, Ying-Ying Miu, Ya-Fang Liu, Xiao-Xia Wang, Ze-Jun Zhou, Jia-Jia Jin, Qian Li, Shinji Sasada, Takehiro Izumo, Chih-Yen Tu, Wen-Chien Cheng, Matthew Evison, Tang-Feng Lv, Yong Song, written on behalf of the AME Lung Cancer Collaborative Group

Published online: 28 February 2017

PDF Pages: 23-34 Full Text (12203) Open Access