Vol 14, No 3 (March 31, 2025): Translational Lung Cancer Research

Editorial Commentary

Will INSPIRE crown iruplinalkib as a new standard choice in first-line advanced ALK-positive non-small cell lung cancer?
Blerina Resuli, Diego Kauffmann-Guerrero
Translational Lung Cancer Research  
2025;
14
(3)
:653-656
.
 (31 March 2025) 
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Optimizing long-term treatment with ALK inhibitors: balancing efficacy and safety
Ayuka Dai, Takaaki Sasaki
Translational Lung Cancer Research  
2025;
14
(3)
:657-661
.
 (31 March 2025) 
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Original Article

ANKRD11 as a potential biomarker for brain metastasis from lung adenocarcinoma via cerebrospinal fluid liquid biopsy
Qinhong Sun, Peng Xing, Qinglin Wang, Zhijun Xia, Jianyu Li, Zhitong Li, Fancheng Meng, Tongyan Liu, Siwei Wang, Rong Yin
Translational Lung Cancer Research  
2025;
14
(3)
:662-676
.
 (31 March 2025) 
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Persistent and novel changes in plasma microRNA profiles in patients with non-small cell lung cancer following tumour resection
Maria Sromek, Maciej Głogowski, Magdalena Chechlińska, Mariusz Kulińczak, Michalina Zajdel, Natalia Żeber-Lubecka, Aneta Bałabas, Łukasz M. Szafron, Maria Kulecka, Jan K. Siwicki
Translational Lung Cancer Research  
2025;
14
(3)
:677-706
.
 (31 March 2025) 
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Amivantamab as a salvage therapy post-EGFR-tyrosine kinase inhibitor failure in patients with mutated EGFR non-small cell lung cancer
Bilal Krayim, Waleed Kian, Maria Spector, Inbal Granot, Julia Dudnik, Michal Nissim, Dolev Kahala, Areen Abu Remilah, Naama R. Bogot, Gleb Kornev, Noam Asna, Nir Peled, Laila C. Roisman
Translational Lung Cancer Research  
2025;
14
(3)
:707-717
.
 (31 March 2025) 
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Circulating lung cancer exosomes damage the niche of intestinal stem cells
Ke Wang, Lu Xu, Jianhua Feng, Shubin Wang, Xi Wang, Junyi Zou, Zhenni Xu, Lingxiao Huang, Wenjun Jiang, Jin Zhou, Xudan Lei, Dengqun Liu
Translational Lung Cancer Research  
2025;
14
(3)
:718-735
.
 (31 March 2025) 
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Predicting survival in small cell lung cancer patients undergoing various treatments: a machine learning approach
Ziran Zhao, Xi Cheng, Yibo Gao, Fengwei Tan, Qi Xue, Shugeng Gao, Jie He
Translational Lung Cancer Research  
2025;
14
(3)
:736-748
.
 (31 March 2025) 
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Prognostic significance of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in second-line immunotherapy for patients with non-small cell lung cancer
Magdalena Knetki-Wróblewska, Aleksandra Grzywna, Paweł Krawczyk, Kamila Wojas-Krawczyk, Izabela Chmielewska, Tomasz Jankowski, Janusz Milanowski, Maciej Krzakowski
Translational Lung Cancer Research  
2025;
14
(3)
:749-760
.
 (31 March 2025) 
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Connecting the dots: (RANKL+) extracellular vesicle count in blood plasma in relation to bone metastases, skeletal related events and osimertinib treatment in patients with EGFR mutated non-small cell lung cancer
Anita J. W. M. Brouns, Iris J. Robbesom-van den Berge, Sophie M. Ernst, Christi M. J. Steendam, Wouter W. Woud, Liang Wu, Anne-Marie C. Dingemans, Lizza E. L. Hendriks, Marjolein van Driel
Translational Lung Cancer Research  
2025;
14
(3)
:761-774
.
 (31 March 2025) 
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A better option for localization of multiple pulmonary nodules in the ipsilateral lung: electromagnetic navigation bronchoscopy-guided preoperative localization
Rui Wang, Yongjiang Chen, Chudong Wang, Zijian Li, Yunpeng Zhong, Yunjuan Liang, Shuben Li
Translational Lung Cancer Research  
2025;
14
(3)
:775-784
.
 (31 March 2025) 
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Short-term peri- and intra-tumoral CT radiomics to predict immunotherapy response in advanced non-small cell lung cancer
Ting Wang, Lei Chen, Xiao Bao, Zijuan Han, Zezhou Wang, Shengdong Nie, Yajia Gu, Jing Gong
Translational Lung Cancer Research  
2025;
14
(3)
:785-797
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 (31 March 2025) 
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Diagnostic utility of bronchoscopy for newly emerging peripheral pulmonary lesions after pulmonary resection
Takahiro Suzuki, Yuji Matsumoto, Hideaki Furuse, Keigo Uchimura, Tatsuya Imabayashi, Takaaki Tsuchida
Translational Lung Cancer Research  
2025;
14
(3)
:798-809
.
 (31 March 2025) 
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Closer proximity of pre-treatment CD4+ T cells to CD8+ T cells favor response to neoadjuvant immunotherapy in patients with PD-L1 low-expressing non-small cell lung cancer
Liying Yang, Jiaxiao Geng, Hao Yang, Miaoqing Zhao, Hongtu Yuan, Yushan Yan, Li Wu, Fanghan Cao, Ligang Xing, Xiaorong Sun
Translational Lung Cancer Research  
2025;
14
(3)
:810-823
.
 (31 March 2025) 
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Single cell RNA-seq and bulk RNA-seq analysis identifies MUC1 as a key gene for lung adenocarcinoma to neuroendocrine transformation
Hongxia Li, Tiantian Yang, Yu Chen, Zhiqin Xie
Translational Lung Cancer Research  
2025;
14
(3)
:824-841
.
 (31 March 2025) 
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Nomogram based on computed tomography radiomics features and clinicopathological factors to predict the prognosis of patients with non-small cell lung cancer receiving immune checkpoint inhibitor rechallenge
Junfeng Zhao, Ying Li, Ruyue Li, Xiujing Yao, Xue Dong, Lin Su, Yintao Li
Translational Lung Cancer Research  
2025;
14
(3)
:842-856
.
 (31 March 2025) 
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Integrated multiomics machine learning and mediated Mendelian randomization investigate the molecular subtypes and prognosis lung squamous cell carcinoma
Zhanghao Huang, Jing Li, You Lang Zhou, Jiahai Shi
Translational Lung Cancer Research  
2025;
14
(3)
:857-877
.
 (31 March 2025) 
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Targeting of arachidonic acid-modulated autophagy to enhance the sensitivity of ROS1+ or ALK+ non-small cell lung cancer to crizotinib therapy
Hui Jie, Hongjin Lai, Zihuai Wang, Min Yi, Yi Liu, Edyta Maria Urbanska, Eric Santoni-Rugiu, Shiyou Wei, Yuhao Chen, Chuan Li, Tengyong Wang, Nanzhi Luo, Lunxu Liu, Senyi Deng, Chenglin Guo
Translational Lung Cancer Research  
2025;
14
(3)
:878-896
.
 (31 March 2025) 
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Enhancing the precision of auxiliary diagnosis for lung cancer through use of SHOX2 and RASSF1A methylation status in lung biopsy and lymph node biopsy specimens
Ping Gu, Yue Wang, Chunlei Shi, Yuqing Chen, Jialin Qian, Yanjie Niu, Hai Zhang, Yunxia Bao, Bin She, Xiaosha Ren, Iyare Izevbaye, Baohui Han, Hua Zhong, Yu Dong
Translational Lung Cancer Research  
2025;
14
(3)
:897-911
.
 (31 March 2025) 
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Analysis of baseline interstitial lung abnormality on the risk of checkpoint inhibitor-related pneumonitis and survival in advanced non-small cell lung cancer patients treated with first-line PD-1/PD-L1 inhibitors
Yu Li, Shuo Liang, Yanjun Du, Jun Yao, Yuxin Jiang, Wanjun Lu, Qiuxia Wu, Fumihiro Yamaguchi, Marko Jakopović, Wolfgang M. Brueckl, Dong Wang, Fang Zhang, Qin Wang, Tangfeng Lv, Ping Zhan
Translational Lung Cancer Research  
2025;
14
(3)
:912-930
.
 (31 March 2025) 
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Palliative surgery is effective in patients with EGFR-mutant lung adenocarcinoma with pleural metastasis
Yue Liu, Yifei Zhou, Shuangyi Li, Qianxin Zhou, Jun Li, Nobuhiro Kanaji, Sara Ricciardi, Raja M. Flores, Marcello Migliore, Kakeru Hisakane, Yuming Zhu, Wenxin He, Linsong Chen, Dongliang Bian
Translational Lung Cancer Research  
2025;
14
(3)
:931-939
.
 (31 March 2025) 
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Identification and validation of crotonylation-related diagnostic markers for lung adenocarcinoma via weighted correlation network analysis and machine learning
Bowen Hu, Xin Chen, Dan Zou, Xiaoyue Du, Sitong Feng, Yiwen Shen, Xiaofeng Sha, Feng Jiang, Guoren Zhou, Fan Lin, Lukas Käsmann, Bo Shen
Translational Lung Cancer Research  
2025;
14
(3)
:940-962
.
 (31 March 2025) 
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Neoadjuvant immunochemotherapy demonstrated improved efficacy and comparable safety to neoadjuvant chemotherapy for limited-stage small-cell lung cancer: a cohort study
Lijiang Song, Xiaowei Mao, Haichuan Hu, Hu Zhang, Xinxin Ying, Lichen Zhang, Kai Liu, Huiyong Han, Dongde Li, Zhengfu He
Translational Lung Cancer Research  
2025;
14
(3)
:963-974
.
 (31 March 2025) 
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Review Article

Recent advancements in lung cancer research: a narrative review
Fuk Hay Tang, Heylie Y. T. Wong, Phyllis S. W. Tsang, Mabel Yau, Shing Yau Tam, Lawla Law, Katherine Yau, Jade Wong, Fatema Hassan Mustafa Farah, Jacky Wong
Translational Lung Cancer Research  
2025;
14
(3)
:975-990
.
 (31 March 2025) 
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Multidisciplinary management of N2 stage III non-small cell lung cancer: opportunities and challenges for radiation oncology
Hongcheng Zhu, Daniel G. Schep, Marta Isolano, Piergiorgio Muriana, Sarayut L. Geater, Giulia Veronesi, Fangqiu Fu, Roberto Ferrara, Kuaile Zhao, Alexander V. Louie
Translational Lung Cancer Research  
2025;
14
(3)
:991-1006
.
 (31 March 2025) 
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Clinical application of minimal residual disease detection by ctDNA testing in non-small cell lung cancer: a narrative review
Yishan Wang, Wenjun Shao, Hui Li, Peiyan Zhao, Lin Tian, Liang Zhang, Shaowei Lan, Rui Zhong, Shuang Zhang, Ying Cheng
Translational Lung Cancer Research  
2025;
14
(3)
:1007-1020
.
 (31 March 2025) 
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Case Report

Metachronous development of L858R and T790M EGFR mutations following ALK inhibitor therapy in stage IV lung adenocarcinoma: a case report
So-Yun Kim, Jisoo Lee, Dongil Park, Jeong Eun Lee, Joo-Eun Lee, Hyun-Yi Kim, Da Hyun Kang, Chaeuk Chung
Translational Lung Cancer Research  
2025;
14
(3)
:1021-1031
.
 (31 March 2025) 
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Pathological complete response and long-term survival by pembrolizumab based immunochemotherapy in epidermal growth factor receptor mutated non-small cell lung cancer post-tyrosine kinase inhibitor failure: a case report and tumor microenvironment analysis
Sangtian Liu, Wenhua Liang, Shicui Quan, Qilin Deng, Wenhai Fu, Yalei Zhang, Hong Du, Jianxing He
Translational Lung Cancer Research  
2025;
14
(3)
:1032-1041
.
 (31 March 2025) 
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