Vol 13, No 12 (December 31, 2024) - Translational Lung Cancer Research

Original Article

Anatomic and clinical implications of venous drainage variations in superior segment resections for clinical T1N0 non-small cell lung cancer

Chengyu Bian, Chenghao Fu, Wentao Xue, Yan Gu, Hongchang Wang, Wenhao Zhang, Guang Mu, Mei Yuan, Liang Chen, Qianyun Wang, Jun Wang

PDF Pages: 3256-3266 Full Text (50) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

A novel bioassay reflecting response to immune checkpoint inhibitor therapy in non-small cell lung cancer with malignant pleural effusion

Ayako Takigami, Naoko Mato, Koichi Hagiwara, Makoto Maemondo

PDF Pages: 3267-3277 Full Text (28) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Successful long-term outcome of neoadjuvant sequential targeted therapy and chemotherapy for stage III non-small cell lung carcinoma: 10 case series

Masaya Aoki, Ryo Miyata, Go Kamimura, Shoichiro Morizono, Takuya Tokunaga, Aya Harada-Takeda, Koki Maeda, Toshiyuki Nagata, Kazuhiro Ueda

PDF Pages: 3278-3288 Full Text (38) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Health-related quality of life analysis from ENTER, a randomized, controlled phase III trial of whole-brain radiotherapy with and without concurrent erlotinib in NSCLC with brain metastases

Fei Tang, Jingyi Zhang, Zaicheng Xu, Yu Zhang, Xiaoyue Zhang, Yuan Peng, Zhenzhou Yang

PDF Pages: 3289-3302 Full Text (46) Reporting Checklist Trial Protocol Data Sharing Statement Peer Review File COI Form Open Access

Radiomicsmetabolic signature profiles for advanced non-small cell lung cancer with chemoimmunotherapy by reflecting biological function and survival

Yuxin Jiang, Tao Liu, Ke Xu, Wanjun Lu, Qinpei Cheng, Jingyuan Xie, Mo Chen, Xiangyu Bian, Tangfeng Lv, Jiang Wu, Yong Song, Ping Zhan

PDF Pages: 3303-3322 Full Text (42) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Quantitative peripheral live single T-cell dynamic polyfunctionality profiling predicts lung cancer checkpoint immunotherapy treatment response and clinical outcomes

Zuan-Fu Lim, Xiaoliang Wu, Lin Zhu, Heidar Albandar, Maria Hafez, Chenchen Zhao, Mohammed Almubarak, Matthew Smolkin, Hong Zheng, Sijin Wen, Patrick C. Ma

PDF Pages: 3323-3343 Full Text (29) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Osimertinib as a neoadjuvant therapy in resectable EGFR-mutant non-small cell lung cancer: a real-world, multicenter retrospective study

Jialong Li, Youyu Wang, Zerui Zhao, Sihua Wang, Wanpu Yan, Xiaohui Chen, Tianxiang Chen, Pengfei Li, Sheng Wang, Qiang Fang, Lin Peng, Yongtao Han, Jian Tang, Xuefeng Leng

PDF Pages: 3344-3351 Full Text (26) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Development and validation of a nomogram for predicting visceral pleural invasion in patients with early-stage non-small cell lung cancer

Qinyue Luo, Hanting Li, Xiaoqing Liu, Yuting Zheng, Tingting Guo, Jun Fan, Na Wang, Xiaoyu Han, Heshui Shi

PDF Pages: 3352-3363 Full Text (35) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

A non-interventional biomarker study in patients with adenocarcinoma of the lung treated with nintedanib plus docetaxel following progression on chemotherapy and/or immunotherapy: LUME-BioNIS

Martin Reck, Konstantinos Syrigos, Skaidrius Miliauskas, Susan C. van’t Westeinde, Bartomeu Massuti, Hannes Buchner, Alexey V. Salnikov, Robert M. Lorence, Anne-Marit Ellingboe, Thomas Kitzing, Keith Kerr

PDF Pages: 3364-3381 Full Text (38) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Efficacy, safety, and quality of life of dabrafenib plus trametinib treatment in Chinese patients with BRAF^V600E mutation-positive metastatic non-small cell lung cancer

Yun Fan, Jianying Zhou, Yuanyuan Zhao, Yan Yu, Nong Yang, Juan Li, Jialei Wang, Jun Zhao, Zhehai Wang, Jun Chen, Tong Zhu, Haifu Li, Vanessa Q. Passos, Denise Bury-Maynard, Li Zhang

PDF Pages: 3382-3391 Full Text (35) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

A prognostic nomogram of non-small cell lung cancer based on tumor marker inflammatory nutrition score

Yan Feng, Han Qiao, Xiaolei Han, Huaping Tang

PDF Pages: 3392-3406 Full Text (40) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Construction of a neutrophil extracellular trap formation-related gene model for predicting the survival of lung adenocarcinoma patients and their response to immunotherapy

Yuan Wang, Shuang Liang, Qian Hong, Juwei Mu, Yuxin Wu, Kexin Li, Yiling Li, Yue Wu, Xiaoying Lou, Danfei Xu, Wei Cui

PDF Pages: 3407-3425 Full Text (41) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Inhibition of miR-9-3p facilitates ferroptosis by activating SAT1/p53 pathway in lung adenocarcinoma

Anqi Wu, Anping Zhang, Tianyi Wang, Jianle Chen, Jiahai Shi

PDF Pages: 3426-3442 Full Text (38) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Prediction of early lung adenocarcinoma spread through air spaces by machine learning radiomics: a cross-center cohort study

Cong Liu, Ao Meng, Xiu-Qing Xue, Yu-Feng Wang, Chao Jia, Da-Peng Yao, Yun-Jian Wu, Qian Huang, Ping Gong, Xiao-Feng Li

PDF Pages: 3443-3459 Full Text (40) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

A retrospective study of the efficacy and safety of immune checkpoint inhibitors combined with chemotherapy for the treatment of SMARCA4-deficient thoracic tumors

Bin Wang, Heng You, Dongfan Ye, Yuanyue Yi, Yu Liu, Bin Qing, Chuangye Wang, Jincheng Liu, Jian Zhang, Nanbo Wang, Pengfei Wan, Linlin Shen, Zhi Xu

PDF Pages: 3460-3472 Full Text (33) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Effectiveness of artificial intelligence for detecting operable lung cancer on chest radiographs

Hyun Joo Shin, Se Hyun Kwak, Kyeong Yeon Kim, Na Young Kim, Kyungsun Nam, Young Jin Kim, Eun-Kyung Kim, Young Joo Suh, Eun Hye Lee

PDF Pages: 3473-3485 Full Text (43) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Performance of deep learning model and radiomics model for preoperative prediction of spread through air spaces in the surgically resected lung adenocarcinoma: a two-center comparative study

Xiang Wang, Chao Ma, Qinling Jiang, Xuebin Zheng, Jun Xie, Chuan He, Pengchen Gu, Yanyan Wu, Yi Xiao, Shiyuan Liu

PDF Pages: 3486-3499 Full Text (36) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

EGFR inhibitors plus dabrafenib and trametinib in patients with EGFR-mutant lung cancer and resistance mediated by BRAF^V600E mutation: a multi-center real-world experience in China

Wenyue Yang, Xiangran Feng, Jian Ni, Xin Zhang, Hui Yu, Xianghua Wu, Huijie Wang, Xinmin Zhao, Zhihuang Hu, Bo Yu, Yao Zhang, Ying Lin, Yi Xiang, Jialei Wang

PDF Pages: 3500-3512 Full Text (37) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Long-term high fat diet aggravates the risk of lung fibrosis and lung cancer: transcriptomic analysis in the lung tissues of obese mice

Jihyun Park, Danbi Jo, Seo Yoon Choi, Sumin Oh, Yoon Seok Jung, Oh Yoen Kim, Juhyun Song

PDF Pages: 3513-3525 Full Text (48) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Validation of T stage classification strategy for >2 cm ground-glass opacity non-small cell lung cancer: a retrospective cohort study

Yiming Li, Zhenyu Yang, Hui Jie, Liying Zhang, Chenglin Guo, Chengwu Liu, Qiang Pu, Lunxu Liu

PDF Pages: 3526-3537 Full Text (37) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Characteristics of the immune microenvironment and their clinical significance in lung adenocarcinoma patients with different ALK fusion variants

Yinbo Xiao, Hao Wang, Junliang Lu, Junyi Pang, Shiyi Liu, Yang Zhou, Xiaohua Shi, Zhiyong Liang

PDF Pages: 3538-3554 Full Text (34) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Spontaneous ventilation video-assisted thoracoscopic surgery for octogenarian non-small cell lung cancer patients: a non-inferiority study

Yulin Zhao, Xuanzhuang Lu, Runchen Wang, Keyao Dai, Huiwen Yu, Chongde Pan, Jiaqin Zhang, Xianzhe Fan, Yanwei Lin, Hengrui Liang, Jianxing He, Wei Wang, Lan Lan

PDF Pages: 3555-3565 Full Text (32) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Enhancing the prediction of KRAS mutation status in Asian lung adenocarcinoma: a comprehensive approach combining clinical, dual-energy spectral computed tomography, and radiomics features

Jing-Wen Ma, Cai-Xing Yuan, Shan Muhammad, Yan-Mei Wang, Lin-Lin Qi, Jiu-Ming Jiang, Xu Jiang, Lei Miao, Meng-Wen Liu, Xin Liang, Tian Qiu, Li Zhang, Meng Li

PDF Pages: 3566-3578 Full Text (39) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Machine learning-based radiomics for guiding lymph node dissection in clinical stage I lung adenocarcinoma: a multicenter retrospective study

Hao Zhang, Yuan Li, Sikai Wu, Yue Peng, Yang Liu, Shugeng Gao

PDF Pages: 3579-3589 Full Text (49) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Discrepancies in PD-L1 expression, lymphocyte infiltration, and tumor mutational burden in non-small cell lung cancer and matched brain metastases

Yanhui Zhang, Runfen Cheng, Tingting Ding, Jianghua Wu

PDF Pages: 3590-3602 Full Text (31) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Radiotherapy for oligoprogressive disease in non-small cell lung cancer treated with pembrolizumab in first-line setting: a retrospective study

Camille Santonja, Paul Gougis, Elise Dumas, Camille Rolland Debord, Patrick Merle, Aurélie Belliere, Luca Campedel, Baptiste Abbar

PDF Pages: 3603-3615 Full Text (37) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Quantitative evaluation of accumulated and planned dose deviations in patients undergoing gated and non-gated lung stereotactic body radiation therapy patients: a retrospective analysis

Shuangyan Yang, Bin Su, Hui Liu

PDF Pages: 3616-3628 Full Text (41) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Prognostic value of ground-glass opacity on computed tomography for patients with pathological stage IA3 lung adenocarcinoma: a multicenter retrospective cohort study

Chao Chen, Shao-Jun Xu, Xiao-Qiang Du, Jia-Hua Tu, Ren-He Yan, Hui Chen, Duilio Divisi, Sang-Won Um, Yun-Fan Luo, Zhi-Fan Zhang, Cheng-Xiong You, Shao-Bin Yu, Shu-Chen Chen

PDF Pages: 3629-3641 Full Text (27) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Development of an AI model for predicting hypoxia status and prognosis in non-small cell lung cancer using multi-modal data

Lina Zhou, Chenkai Mao, Tingting Fu, Xiao Ding, Luca Bertolaccini, Ao Liu, Junjun Zhang, Shicheng Li

PDF Pages: 3642-3656 Full Text (42) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Identification and validation of pyroptosis patterns with a novel quantification system for the prediction of prognosis in lung squamous cell carcinoma

Xianyu Qin, Jiayan Wu, Fei Qin, Yuzhen Zheng, Junguo Chen, Zui Liu, Jian Tan, Weijie Cai, Shiyun He, Bozhu Jian, Haosheng Zheng, Hongying Liao

PDF Pages: 3657-3674 Full Text (35) Reporting Checklist Peer Review File COI Form Open Access

Efficacy and safety of consolidative thoracic radiotherapy after first-line chemoimmunotherapy in patients with extensive-stage small-cell lung cancer: a retrospective cohort study

Lin Zheng, Yang Yang, Fan Bu, Ruizhi Ye, Fengming Zhang, Zhixiang Ji, Xirong Zhu, Hong Chen, Rongjun Shao, Lidan Liu, Xixi Ying, Lingying Zhu, Enyu Wang, Jifeng Feng, Zhiyong Shi, Jun Fang, Yuezhen Wang, Zhirui Zhou, Guangxian You

PDF Pages: 3675-3691 Full Text (52) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Review Article

Fuel for thought: targeting metabolism in lung cancer

Jaime L. Schneider, SeongJun Han, Christopher S. Nabel

PDF Pages: 3692-3717 Full Text (37) Peer Review File COI Form Open Access

Emerging insights into STK11, KEAP1 and KRAS mutations: implications for immunotherapy in patients with advanced non-small cell lung cancer

Magdalena Knetki-Wróblewska, Kamila Wojas-Krawczyk, Paweł Krawczyk, Maciej Krzakowski

PDF Pages: 3718-3730 Full Text (45) Peer Review File COI Form Open Access

Impact of lymph node involvement in pulmonary carcinoids: a narrative review

Michał Dziedzic, Marcin Cackowski, Maciej Pawlica, Zuzanna Gabrysz, Krzysztof Gofron, Tomasz Marjański

PDF Pages: 3731-3740 Full Text (49) Reporting Checklist Peer Review File COI Form Open Access

Lung cancer organoid-based drug evaluation models and new drug development application trends

Eunyoung Lee, Sang-Yun Lee, Yu-Jeong Seong, Bosung Ku, Hyeong Jun Cho, Kyuhwan Kim, Yongki Hwang, Chan Kwon Park, Joon Young Choi, Sung Won Kim, Seung Joon Kim, Jeong Uk Lim, Chang Dong Yeo, Dong Woo Lee

PDF Pages: 3741-3763 Full Text (65) Peer Review File COI Form Open Access