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New Impact Factor for Translational Lung Cancer Research: 4

We are pleased to announce that the Translational Lung Cancer Research (TLCR) has attained its latest impact factor update for the 2023 citation year: 4.

Translational Lung Cancer Research 2023 CiteScore Released: 7.2

We are pleased to announce that the Translational Lung Cancer Research (TLCR) has received its 2023 CiteScore: 7.2, ranking 92 out of 404 journals in the Oncology category.

Furthermore, we are delighted to highlight the remarkable achievements made by all AME journals in the CiteScore ranking.

Interviews with Outstanding Authors (2024)

In 2024, many authors make outstanding contributions to our journal. Their articles published with us have received very well feedback in the field and stimulate a lot of discussions and new insights among the peers.

Hereby, we would like to highlight some of our outstanding authors, with a brief interview of their thoughts and insights as authors. Allow us to express our heartfelt gratitude for their tremendous effort and valuable contributions to the scientific process.

Reviewer of the Month (2024)

In 2024, TLCR reviewers continue to make outstanding contributions to the peer review process. They demonstrated professional effort and enthusiasm in their reviews and provided comments that genuinely help the authors to enhance their work.

Hereby, we would like to highlight some of our outstanding reviewers, with a brief interview of their thoughts and insights as a reviewer. Allow us to express our heartfelt gratitude for their tremendous effort and valuable contributions to the scientific process.

TLCR Annual Report 2023

Welcome to the 2023 annual report for Translational Lung Cancer Research. In 2023, the TLCR has continued its mission to increase the quality and impact of the journal, and to provide readers with a novel, well-organized, informative, enlightening and educational journal.

We would like to sincerely thank our Editorial Board Members, Guest editors, Reviewers, Authors, Readers for all your supports and contributions to TLCR in 2023, and we look forward to continuing our work with you in the new year.

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Vol 13, No 9 (September, 2024)

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Editorial Commentary

Circulating tumor DNA (ctDNA)—the next generation biomarker in non-small cell lung cancer patients treated with immunotherapy?

Per Hydbring

PDF Pages: 2103-2105 Full Text (132) Peer Review File COI Form Open Access

Original Article

Utility of atezolizumab plus bevacizumab, carboplatin, and paclitaxel combination for the treatment of advanced non-squamous non-small cell lung cancer patients with malignant pleural effusion

Kakeru Hisakane, Kenichiro Atsumi, Masahiro Seike, Takashi Hirose

PDF Pages: 2106-2115 Full Text (209) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

TFAP2A-activated ITGB4 promotes lung adenocarcinoma progression and inhibits CD4⁺/CD8⁺ T-cell infiltrations by targeting NF-κB signaling pathway

Cheng Pan, Zhibo Wang, Qi Wang, Hongshun Wang, Xiaheng Deng, Liang Chen, Zhihua Li

PDF Pages: 2116-2138 Full Text (192) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

IL-1 receptor-associated kinase 3 (IRAK3) in lung adenocarcinoma predicts prognosis and immunotherapy resistance: involvement of multiple inflammation-related pathways

Yang Zhou, Wei Rao, Zhao Li, Wei Guo, Fei Shao, Zhen Zhang, Hao Zhang, Tiejun Liu, Zitong Li, Fengwei Tan, Qi Xue, Shugeng Gao, Jie He

PDF Pages: 2139-2161 Full Text (234) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Ten-year survival outcomes of video-assisted thoracic surgery vs. open major lung resection for stage I–III non-small cell lung cancer: a large cohort study in China

Yiming Li, Jiandong Mei, Zhenyu Yang, Chenglin Guo, Chengwu Liu, Hu Liao, Lin Ma, Feng Lin, Yidan Lin, Yong Yuan, Yunke Zhu, Yuyang Xu, Zheng Liu, Kaidi Li, Yang Hu, Yun Wang, Nan Chen, Zhu Wu, Chuan Li, Liang Xia, Jian Zhou, Xiaolong Zhang, Cheng Shen, Qiang Pu, Lunxu Liu

PDF Pages: 2162-2174 Full Text (146) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Diagnostic efficacy of cryobiopsy for peripheral pulmonary lesions with ground-glass opacity: a propensity score-matched analysis

Hideaki Furuse, Yuji Matsumoto, Toshiyuki Nakai, Midori Tanaka, Kanako Nishimatsu, Keigo Uchimura, Tatsuya Imabayashi, Takaaki Tsuchida

PDF Pages: 2175-2186 Full Text (145) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Incidence, prevalence, and survival of lung cancer in the United Kingdom from 2000–2021: a population-based cohort study

George Corby, Nicola L. Barclay, Eng Hooi Tan, Edward Burn, Antonella Delmestri, Talita Duarte-Salles, Asieh Golozar, Wai Yi Man, Ilona Tietzova, Daniel Prieto-Alhambra, Danielle Newby

PDF Pages: 2187-2201 Full Text (217) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Trends in the prescription of immune checkpoint inhibitors for non-small cell lung cancer in the Netherlands from 2016 to 2020, a national cancer registry analysis

Erick Suazo-Zepeda, Willemijn J. Maas, Petra C. Vinke, T. Jeroen N. Hiltermann, Mieke J. Aarts, Geertruida Hendrika de Bock, Marjolein A. Heuvelmans

PDF Pages: 2202-2211 Full Text (114) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Efficacy of first-line immune checkpoint inhibitors in pulmonary sarcomatoid carcinoma

Gary Birsen, Valérie Gounant, Nicolas Girard, Jacques Cadranel, Isabelle Monnet, Christine Raynaud-Donzel, Elizabeth Fabre, Etienne Giroux Leprieur, Karen Leroy, Diane Damotte, Marco Alifano, Jennifer Arrondeau, Isabelle Cremer, Jeanne Chapron, Marie Wislez

PDF Pages: 2212-2221 Full Text (207) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Molecular subtypes and prognostic factors of lung large cell neuroendocrine carcinoma

Tingting Liu, Xueyuan Chen, Silang Mo, Ting Zhou, Wenjuan Ma, Gang Chen, Xiang Chen, Mengting Shi, Yuwen Yang, Yan Huang, Hongyun Zhao, Wenfeng Fang, Yunpeng Yang, Jing Li, Li Zhang, Yuanyuan Zhao

PDF Pages: 2222-2235 Full Text (140) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Lymph nodes rather than pleural metabolic activity in ¹⁸F-FDG PET/CT correlates with malignant pleural effusion recurrence in advanced non-small cell lung cancer

Yuxin Jiang, Tao Liu, Ke Xu, Qinpei Cheng, Wanjun Lu, Jingyuan Xie, Mo Chen, Yu Li, Yanjun Du, Shuo Liang, Yong Song, Jiang Wu, Tangfeng Lv, Ping Zhan

PDF Pages: 2236-2253 Full Text (182) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Establishment of a survival predictive model for patients with two synchronous multiple primary lung cancers: a multicenter cohort analysis

Ying Ji, Qing Zhao, Yi Liu, Bin Qiu, Guangyu Bai, Siyuan Ai, Wei Feng, Ligong Yuan, Xin Wang, Lulu Rong, Hua Fu, Huihui Xie, Linlin Qi, Ye Tao, Longyu Jin, Jing Zhou, Bin Hu, Shugeng Gao

PDF Pages: 2254-2268 Full Text (164) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Establishing a predictive model for tumor mutation burden status based on ¹⁸F-FDG PET/CT and clinical features of non-small cell lung cancer patients

Zheng Chen, Xueping Chen, Linjun Ju, Yue Li, Wenbo Li, Hua Pang

PDF Pages: 2269-2281 Full Text (120) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Serum tumor markers and outcomes in lung cancer patients with brain metastases: a retrospective longitudinal cohort study

Yingtong Liu, Shuang Dai, Zheran Liu, Ling He, Lili Zhu, Zijian Qin, Haohan Fan, Fang Fang, Yuping Xie, Xingchen Peng

PDF Pages: 2282-2295 Full Text (160) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Tremelimumab and durvalumab with chemotherapy in first-line treatment for metastatic non-small cell lung cancer: a US-based cost-effectiveness analysis

Ziying Zhao, Xiaohui Zeng, Zhen Zhou, Qiao Liu

PDF Pages: 2296-2306 Full Text (139) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

TRIM27 revealing by tumor educated platelet RNA-sequencing, as a potential biomarker for malignant ground-glass opacities diagnosis mediates glycolysis of non-small cell lung cancer cells partially through HOXM1

Yan Hu, Chao Zeng, Jina Li, Siying Ren, Mengqi Shao, Weixuan Lei, Junqi Yi, Wei Han, Jieming Cao, Jian Zou, Quanming Fei, Zeyu Cheng, Wenliang Liu

PDF Pages: 2307-2325 Full Text (124) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Prognostic value of circulating proteins at diagnosis among patients with lung cancer: a comprehensive analysis by smoking status

Xiaoshuang Feng, Hilary A. Robbins, Anush Mukeriya, Lenka Foretova, Ivana Holcatova, Vladimir Janout, Jolanta Lissowska, Miodrag Ognjanovic, Beata Swiatkowska, David Zaridze, Paul Brennan, Mattias Johansson, Mahdi Sheikh

PDF Pages: 2326-2339 Full Text (140) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Establishment of lung cancer cell lines and tumorigenesis in mice from malignant pleural effusion in patients with lung cancer

Nobuhiro Kanaji, Masanao Yokohira, Takuya Inoue, Naoki Watanabe, Hitoshi Mizoguchi, Yuta Komori, Kosuke Kawada, Norimitsu Kadowaki

PDF Pages: 2340-2351 Full Text (190) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Stem-like exhausted CD8 T cells in pleural effusions predict improved survival in non-small cell lung cancer (NSCLC) and mesothelioma

Linda Ye, Heeju Ryu, David Granadier, Long T. Nguyen, Yannick Simoni, Ian Dick, Tina Firth, Ebony Rouse, Peter Chiang, Y. C. Gary Lee, Bruce W. Robinson, Jenette Creaney, Evan W. Newell, Alec J. Redwood

PDF Pages: 2352-2372 Full Text (209) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

A multi-level investigation of the genetic relationship between gastroesophageal reflux disease and lung cancer

Dongsheng Wu, Jian Zhou, Lujia Song, Quan Zheng, Tengyong Wang, Zhizhen Ren, Yuchen Huang, Shuqiao Liu, Lunxu Liu

PDF Pages: 2373-2387 Full Text (214) Reporting Checklist Peer Review File COI Form Open Access

Association between fruit intake and non-small cell lung cancer: a Mendelian randomization study

Chongde Pan, Ying Du, Yu Jiang, Yuechun Lin, Yulin Zhao, Huiwen Yu, Hengrui Liang, Wanzhe Liao, Xin Xu, Ying Huang

PDF Pages: 2388-2394 Full Text (189) Reporting Checklist Peer Review File COI Form Open Access

Tumor immune microenvironment analysis of non-small cell lung cancer development through multiplex immunofluorescence

Jiaping Zhao, Yu Lu, Zhaofeng Wang, Haiying Wang, Ding Zhang, Jinping Cai, Bei Zhang, Junling Zhang, Mengli Huang, Andreas Pircher, Krishna H. Patel, Honggang Ke, Yong Song

PDF Pages: 2395-2410 Full Text (104) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Effect of laterality on the postoperative survival of non-small cell lung cancer patients undergoing pneumonectomy

Zi-Ming Wang, Liang Guo, Yang Yang, Bo Tao, Wen-Qiang Zhang, Diego Gonzalez-Rivas, Jens-C Rueckert, Chee Yik Er, Calvin S. H. Ng, Moshe Lapidot, Gaetano Rocco, Mahmoud Ismail, Chen-Lu Yang, De-Ping Zhao

PDF Pages: 2411-2423 Full Text (150) Reporting Checklist Peer Review File COI Form Open Access

Histopathologic pattern and molecular risk stratification are associated with prognosis in patients with stage IB lung adenocarcinoma

Weiran Liu, Chen Chen, Qiang Zhang, Jiping Xie, Xinyi Wu, Zhenfa Zhang, Lin Shao, Haiwei Du, Songan Chen, Hirokazu Iso, Kakeru Hisakane, Dongsheng Yue, Bin Zhang

PDF Pages: 2424-2434 Full Text (116) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

EGFR mutations in patients with lung adenocarcinoma and malignant pleural effusion: a propensity score-matched analysis of a single-center database

Qiwei Yang, Ziyi Wang, Qiang Fu, Xiaohai Hu, Liang Chen, Weiyang Chen, Ling Lv, Zhenghua Liu, Wanfu Men, Danni Li, Wenya Li

PDF Pages: 2435-2447 Full Text (128) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Case Report

Double immune checkpoint inhibitor therapy for unresectable pleural mesothelioma rarely induces hyperprogressive disease: a case report

Gaspard Naulleau, Isabelle Monnet, Gaëlle Rousseau-Bussac, Florent Vinas, Gilles Mangiapan, Laurence Jabot, Amel Boudjemaa, Christos Chouaïd, Jean-Bernard Auliac, Jean-Baptiste Assié

PDF Pages: 2448-2452 Full Text (152) Reporting Checklist Peer Review File COI Form Open Access

ALK-tyrosine kinase inhibitor intrinsic resistance due to de novo MET-amplification in metastatic ALK-rearranged non-small cell lung cancer effectively treated by alectinib-crizotinib combination—case report

Edyta M. Urbanska, Morten Grauslund, Siv M. S. Berger, Junia C. Costa, Peter R. Koffeldt, Jens B. Sørensen, Eric Santoni-Rugiu

PDF Pages: 2453-2462 Full Text (184) Reporting Checklist Peer Review File COI Form Open Access

Images in Clinical Medicine

Squamous-cell carcinoma of the recipient’s explanted lung

Yuan Zeng, Guilin Peng, Chao Yang, Mengyang Liu, Weixue Cui, Jinzhu Mao, Jianxing He, Xin Xu

PDF Pages: 2463-2465 Full Text (214) Peer Review File COI Form Open Access

Review Articles

Management of ground-glass opacities: should all pulmonary lesions with ground-glass opacity be surgically resected?

Yoshihisa Kobayashi, Tetsuya Mitsudomi

Published online: 22 October 2013

PDF Pages: 354-363 Full Text (335668) Open Access

Editorial Commentary

Ground glass nodules with 5 years’ stability can grow after 10-year follow-up: do genetic features determine the fate?

Yoshihisa Kobayashi, Tetsuya Mitsudomi

Published online: 31 December 2019

PDF Pages: S425-S427 Full Text (71628) Open Access

Review Articles

Irreversible EGFR-TKIs: dreaming perfection

Lorenza Landi, Federico Cappuzzo

Published online: 14 January 2013

PDF Pages: 40-49 Full Text (69086) Open Access

Review Article

Non-small cell lung cancer: current treatment and future advances

Cecilia Zappa, Shaker A. Mousa

Published online: 30 June 2016

PDF Pages: 288-300 Full Text (68946) Open Access

Review Article

Pulmonary ground-glass opacity: computed tomography features, histopathology and molecular pathology

Jian-Wei Gao, Stefania Rizzo, Li-Hong Ma, Xiang-Yu Qiu, Arne Warth, Nobuhiko Seki, Mizue Hasegawa, Jia-Wei Zou, Qian Li, Marco Femia, Tang-Feng Lv, Yong Song, written on behalf of the AME Lung Cancer Collaborative Group

Published online: 28 February 2017

PDF Pages: 68-75 Full Text (51963) Open Access

Review Article

Recurrence after surgery in patients with NSCLC

Hidetaka Uramoto, Fumihiro Tanaka

Published online: 28 August 2014

PDF Pages: 242-249 Full Text (42117) Open Access

Review Article

Lung cancer prediction using machine learning and advanced imaging techniques

Timor Kadir, Fergus Gleeson

Published online: 14 June 2018

PDF Pages: 304-312 Full Text (41120) Open Access

Review Article

Targeted therapy for non-small cell lung cancer: current standards and the promise of the future

Bryan A. Chan, Brett G.M. Hughes

Published online: 24 February 2015

PDF Pages: 36-54 Full Text (40756) Open Access

Review Article

The past, present and future of immunotherapy against tumor

Tao Jiang, Caicun Zhou

Published online: 24 June 2015

PDF Pages: 253-264 Full Text (38857) Open Access

Review Article

Treatment of uncommon EGFR mutations in non-small cell lung cancer: new evidence and treatment

Tianli Zhang, Bing Wan, Yuan Zhao, Chuling Li, Hongbing Liu, Tangfeng Lv, Ping Zhan, Yong Song

Published online: 30 June 2019

PDF Pages: 302-316 Full Text (36163) Open Access

Review Article

Ground-glass nodules of the lung in never-smokers and smokers: clinical and genetic insights

Yoshihisa Kobayashi, Chiara Ambrogio, Tetsuya Mitsudomi

Published online: 28 August 2018

PDF Pages: 487-497 Full Text (33030) Chinese (2865) Open Access

Review Articles

KRAS mutant NSCLC, a new opportunity for the synthetic lethality therapeutic approach

Javier de Castro Carpeño, Cristóbal Belda-Iniesta

Published online: 03 April 2013

PDF Pages: 142-151 Full Text (31883) Open Access

Review Article

Molecular testing strategies in non-small cell lung cancer: optimizing the diagnostic journey

Jeffrey P. Gregg, Tianhong Li, Ken Y. Yoneda

Published online: 30 June 2019

PDF Pages: 286-301 Full Text (30368) Open Access

Review Article on Update on Pathology and Predictive Biomarkers of Lung Cancer

Biology of invasive mucinous adenocarcinoma of the lung

Yoon Jin Cha, Hyo Sup Shim

Published online: 11 October 2017

PDF Pages: 508-512 Full Text (29517) Open Access

Review Article

The epidemiology of lung cancer

Patricia M. de Groot, Carol C. Wu, Brett W. Carter, Reginald F. Munden

Published online: 14 June 2018

PDF Pages: 220-233 Full Text (29038) Open Access

Review Articles

New TNM classification: achievements and hurdles

Peter Goldstraw

Published online: 17 August 2013

PDF Pages: 264-272 Full Text (28367) Open Access

Consensus

Tubeless video-assisted thoracic surgery for pulmonary ground-glass nodules: expert consensus and protocol (Guangzhou)

Jianxing He, Hengrui Liang, Wei Wang, Andrey Akopov, Alberto Aiolfi, Keng-Leong Ang, Luca Bertolaccini, Kaican Cai, Qingdong Cao, Baojun Chen, Chang Chen, Chun Chen, Donglai Chen, Fengxia Chen, Jun Chen, Lei Chen, Mingwu Chen, Yongbing Chen, Zhuxing Chen, Chao Cheng, Dong Cui, Fei Cui, Tianyang Dai, Qinglong Dong, Paolo A. Ferrari, Raja M. Flores, Junke Fu, Soichiro Funaki, Marios E. Froudarakis, Xiangfeng Gan, Mingfei Geng, Jialong Guo, Qiang Guo, Yongtao Han, Jintao He, Kaiming He, Kyoji Hirai, Jian Hu, Shuqiao Hu, Jian Huang, Jun Huang, Wenfa Jiang, Kyung Soo Kim, Gabor Kiss, Fanyi Kong, Lan Lan, Xuefeng Leng, Bin Li, Gaofeng Li, Hecheng Li, Hefei Li, Heng Li, Jiwei Li, Xiaoqiang Li, Shuben Li, Yinfen Li, Zhuoyi Li, Yi Liang, Lixia Liang, Wenhua Liang, Yongde Liao, Wanli Lin, Xu Lin, Hongxu Liu, Hui Liu, Jixian Liu, Jun Liu, Xiang Liu, Zihao Liu, Xingzhao Lu, Qingquan Luo, Naiquan Mao, Qi Pan, Dazhi Pang, Jun Peng, Jun Peng, Eugenio Pompeo, Rulin Qian, Kun Qiao, Bassam Redwan, Zi Sang, Wenlong Shao, Jianfei Shen, Weiyu Shen, Sook-Whan Sung, Wenfang Tang, Tianhu Wang, Guangsuo Wang, Haitao Wang, Huien Wang, Jiyong Wang, Wen Wang, Yongyong Wang, Zhenyuan Wang, Li Wei, Wei Wei, Hao Wu, Jie Wu, Zhaohua Xia, Chenyang Xu, Enwu Xu, Hai Xu, Ning Xu, Quan Xu, Rongyu Xu, Shun Xu, Chaokun Yang, Hanyu Yang, Shengli Yang, Jun Yi, Guangjian Zhang, Hao Zhang, Jia Zhang, Man Zhang, Xiao Zhang, Yajie Zhang, Zhe Zhang, Zhifeng Zhang, Honglin Zhao, Jian Zhao, Xiaodong Zhao, Jianping Zhou, Yanran Zhou, Chengchu Zhu, Shaojin Zhu, Xinhai Zhu, Jian Cui, Yubo Yan, Ke-Neng Chen

Published online: 28 August 2021

PDF Pages: 3503-3519 Full Text (27946) COI Form Open Access

Review Article

Lung cancer screening: nodule identification and characterization

Ioannis Vlahos, Konstantinos Stefanidis, Sarah Sheard, Arjun Nair, Charles Sayer, Joanne Moser

Published online: 14 June 2018

PDF Pages: 288-303 Full Text (27548) Open Access

Review Article

Beyond ALK-RET, ROS1 and other oncogene fusions in lung cancer

Takashi Kohno, Takashi Nakaoku, Koji Tsuta, Katsuya Tsuchihara, Shingo Matsumoto, Kiyotaka Yoh, Koichi Goto

Published online: 19 April 2015

PDF Pages: 156-164 Full Text (27419) Open Access

Review Articles

Angiogenesis in cancer: anti-VEGF escape mechanisms

Gerald W. Prager, Marina Poettler, Matthias Unseld, Christoph C. Zielinski

Published online: 18 February 2012

PDF Pages: 14-25 Full Text (27294) Open Access

Full Most Read article list >>

Original Article

Prognostic value of Twist in lung cancer: systematic review and meta-analysis

Junli Zeng, Ping Zhan, Guannan Wu, Wen Yang, Wenjun Liang, Tangfeng Lv, Yong Song

BRAF mutations in non-small cell lung cancer

Peter P. Luk, Bing Yu, Chiu Chin Ng, Belinda Mercorella, Christina Selinger, Trina Lum, Steven Kao, Sandra A. O’Toole, Wendy A. Cooper

The suitability of small biopsy and cytology specimens for EGFR and other mutation testing in non-small cell lung cancer

Shu Wang, Bing Yu, Chiu Chin Ng, Belinda Mercorella, Christina I. Selinger, Sandra A. O’Toole, Wendy A. Cooper

Itraconazole can inhibit malignant pleural effusion by suppressing lymphangiogenesis in mice

Yunfen Wang, Yanwen Yao, Hongbin Liu, Xingqun Ma, Tangfeng Lv, Dongmei Yuan, Xinwu Xiao, Jie Yin, Yong Song

Ratio of maximum standardized uptake value to primary tumor size is a prognostic factor in patients with advanced non-small cell lung cancer

Fangfang Chen, Yanwen Yao, Chunyan Ma, Xingqun Ma, Zhaofeng Wang, Tangfeng Lv, Xinwu Xiao, Jie Yin, Yong Song

Advanced proton beam dosimetry part II: Monte Carlo vs. pencil beam-based planning for lung cancer

Dominic Maes, Jatinder Saini, Jing Zeng, Ramesh Rengan, Tony Wong, Stephen R. Bowen

The cytokinesis-blocked micronucleus assay as a novel biomarker for selection of lung cancer screening participants

Randa A. El-Zein, Carol J. Etzel, Reginald F. Munden

The use of TCP based EUD to rank and compare lung radiotherapy plans: in-silico study to evaluate the correlation between TCP with physical quality indices

Abdulhamid Chaikh, Jacques Balosso

Review Article

Beyond ALK-RET, ROS1 and other oncogene fusions in lung cancer

Takashi Kohno, Takashi Nakaoku, Koji Tsuta, Katsuya Tsuchihara, Shingo Matsumoto, Kiyotaka Yoh, Koichi Goto

Overview of clinicopathologic features of ALK-rearranged lung adenocarcinoma and current diagnostic testing for ALK rearrangement

Hyojin Kim, Jin-Haeng Chung

Neoadjuvant and adjuvant epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy for lung cancer

Haoran Zhai, Wenzhao Zhong, Xuening Yang, Yi-Long Wu

Known and putative mechanisms of resistance to EGFR targeted therapies in NSCLC patients with EGFR mutations—a review

Erin L. Stewart, Samuel Zhixing Tan, Geoffrey Liu, Ming-Sound Tsao

Clinical trials for lung cancer in China

Fei-Yu Niu, Wen-Zhao Zhong, Qing Zhou, Yi-Long Wu

Recurrence after surgery in patients with NSCLC

Hidetaka Uramoto, Fumihiro Tanaka

Prognostic markers in lung cancer: is it ready for prime time?

Chang-Qi Zhu, Ming-Sound Tsao

Potential biomarkers for lung cancer screening

Gabriella Sozzi, Mattia Boeri

Particle therapy in non-small cell lung cancer

Zhongxing Liao, Charles B. Simone II

Computer Aided Nodule Analysis and Risk Yield (CANARY) characterization of adenocarcinoma: radiologic biopsy, risk stratification and future directions

Ryan Clay, Srinivasan Rajagopalan, Ronald Karwoski, Fabien Maldonado, Tobias Peikert, Brian Bartholmai

Immunotherapy and radiation therapy for operable early stage and locally advanced non-small cell lung cancer

Neil K. Taunk, Andreas Rimner, Melissa Culligan, Joseph S. Friedberg, Julie Brahmer, Jamie Chaft

Combining immunotherapy and radiation therapy for small cell lung cancer and thymic tumors

Suchit H. Patel, Andreas Rimner, Roger B. Cohen

Intraoperative near-infrared imaging of mesothelioma

Gregory Thomas Kennedy, Andrew Newton, Jarrod Predina, Sunil Singhal

BAP1, a tumor suppressor gene driving malignant mesothelioma

Mitchell Cheung, Joseph R. Testa

Uncovering the immune tumor microenvironment in non-small cell lung cancer to understand response rates to checkpoint blockade and radiation

Jonathan E. Schoenhals, Steven N. Seyedin, Clark Anderson, Eric D. Brooks, Yun R. Li, Ahmed I. Younes, Sharareh Niknam, Ailin Li, Hampartsoum B. Barsoumian, Maria Angelica Cortez, James W. Welsh

Diagnostic and prognostic biomarkers for malignant mesothelioma: an update

Zhongjian Chen, Giovanni Gaudino, Harvey I. Pass, Michele Carbone, Haining Yang

Immunotherapy for malignant pleural mesothelioma: current status and future directions

Jordan Dozier, Hua Zheng, Prasad S. Adusumilli

Biology and clinical significance of circulating tumor cell subpopulations in lung cancer

Linda O’Flaherty, Harriet Wikman, Klaus Pantel

Routine clinical use of circulating tumor cells for diagnosis of mutations and chromosomal rearrangements in non-small cell lung cancer—ready for prime-time?

Emma Pailler, Vincent Faugeroux, Marianne Oulhen, Cyril Catelain, Françoise Farace

Challenges and unanswered questions for the next decade of circulating tumour cell research in lung cancer

Sumitra Mohan, Francesca Chemi, Ged Brady

Biophysical technologies for understanding circulating tumor cell biology and metastasis

Derrick W. Su, Jorge Nieva

Clinical utility of circulating tumor cells in patients with non-small-cell lung cancer

Marianna Gallo, Antonella De Luca, Monica Rosaria Maiello, Amelia D’Alessio, Claudia Esposito, Nicoletta Chicchinelli, Laura Forgione, Maria Carmela Piccirillo, Gaetano Rocco, Alessandro Morabito, Gerardo Botti, Nicola Normanno

Integrating immunotherapy into chemoradiation regimens for medically inoperable locally advanced non-small cell lung cancer

Salma K. Jabbour, Abigail T. Berman, Charles B. Simone II

Editorial

An alternative way to initiate Notch1 signaling in non-small cell lung cancer

Yi-Lin Yang, David Jablons, Liang You

Combination MET- and EGFR-directed therapy in MET-overexpressing non-small cell lung cancers: time to move on to better biomarkers?

Fernando C. Santini, Siddharth Kunte, Alexander Drilon

Systematic Review and Meta-analysis

Association of the metformin with the risk of lung cancer: a meta-analysis

Li Wang, Yong Song, Guan-Nan Wu, Dong-Mei Yuan

China Lung Cancer Research Highlight

Dll4/Notch1 signaling from tip/stalk endothelial cell specification to stroma-dependent lung tumor inhibition: a flavor of Dll4/Notch1 pleiotropy in tumor cell biology

Maria Felice Brizzi, Paola Defilippi

Editorials

Dulanermin in cancer therapy: Still much to do

Cristina Quintavalle, Gerolama Condorelli

Review Articles

EGFR molecular testing in African-American non-small cell lung cancer patients - a review of discrepant data

Bradley T. Clifford, Pingfu Fu, Nathan A. Pennell, Balazs Halmos, Rom S. Leidner

Copy number gains of FGFR1 and 3q chromosome in squamous cell carcinoma of the lung

Pedro Mendez, Jose Luis Ramirez

Role of HGF/MET axis in resistance of lung cancer to contemporary management

Kanwal Pratap Singh Raghav, Ana Maria Gonzalez-Angulo, George R. Blumenschein Jr

Circulating soluble intercellular adhesion Molecule-1 in lung cancer: a systematic review

Xiaoling Gu, Chunyan Ma, Dongmei Yuan, Yong Song

Ceritinib

Clinical development and approval of second generation ALK inhibitors for ALK rearranged lung cancer

Daniel B. Costa

Onartuzumab plus erlotinib

Targeting MET in NSCLC: looking for a needle in a haystack

Lorenza Landi, Federico Cappuzzo

Nivolumab

Nivolumab (anti-PD-1, BMS-936558, ONO-4538) in patients with advanced non-small cell lung cancer

Arun Rajan, James L. Gulley

Brief Report

The role of Imaging and Radiation Oncology Core for precision medicine era of clinical trial

Ying Xiao, Mark Rosen

Review Article on Update on Pathology and Predictive Biomarkers of Lung Cancer

Biology of invasive mucinous adenocarcinoma of the lung

Yoon Jin Cha, Hyo Sup Shim

Immunohistochemistry for predictive biomarkers in non-small cell lung cancer

Mari Mino- Kenudson

Below are the latest Translational Lung Cancer Research articles published online ahead of print publication.

Erratum

Erratum to EGFR exon 20 insertion mutations and ERBB2 mutations in lung cancer: a narrative review on approved targeted therapies from oral kinase inhibitors to antibody-drug conjugates

Editorial Office

Published online: 12 October 2024

Original Article

Detailed characterization of combination treatment with MET inhibitor plus EGFR inhibitor in EGFR-mutant and MET-amplified non-small cell lung cancer

Youngjoo Lee, Seog-Yun Park, Geon Kook Lee, Hyun-Ju Lim, Yu-Ra Choi, Jaemin Kim, Ji-Youn Han

Published online: 11 October 2024

Journal Highlight more

Translational Lung Cancer Research is an international, peer-reviewed, open-access journal indexed by Science Citation Index Expanded (SCIE) and PubMed/PubMed Central, focusing on cutting-edge development on the transition from preclinical to clinical research, including but not limited to multimodality therapy, markers, imaging, tumor biology, pathology, chemoprevention, and technical advances related to lung cancer and relevant thoracic diseases.