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New Impact Factor for Translational Lung Cancer Research: 4

We are pleased to announce that the Translational Lung Cancer Research (TLCR) has attained its latest impact factor update for the 2023 citation year: 4.

Translational Lung Cancer Research 2023 CiteScore Released: 7.2

We are pleased to announce that the Translational Lung Cancer Research (TLCR) has received its 2023 CiteScore: 7.2, ranking 92 out of 404 journals in the Oncology category.

Furthermore, we are delighted to highlight the remarkable achievements made by all AME journals in the CiteScore ranking.

Interviews with Outstanding Authors (2024)

In 2024, many authors make outstanding contributions to our journal. Their articles published with us have received very well feedback in the field and stimulate a lot of discussions and new insights among the peers.

Hereby, we would like to highlight some of our outstanding authors, with a brief interview of their thoughts and insights as authors. Allow us to express our heartfelt gratitude for their tremendous effort and valuable contributions to the scientific process.

Reviewer of the Month (2024)

In 2024, TLCR reviewers continue to make outstanding contributions to the peer review process. They demonstrated professional effort and enthusiasm in their reviews and provided comments that genuinely help the authors to enhance their work.

Hereby, we would like to highlight some of our outstanding reviewers, with a brief interview of their thoughts and insights as a reviewer. Allow us to express our heartfelt gratitude for their tremendous effort and valuable contributions to the scientific process.

TLCR Annual Report 2023

Welcome to the 2023 annual report for Translational Lung Cancer Research. In 2023, the TLCR has continued its mission to increase the quality and impact of the journal, and to provide readers with a novel, well-organized, informative, enlightening and educational journal.

We would like to sincerely thank our Editorial Board Members, Guest editors, Reviewers, Authors, Readers for all your supports and contributions to TLCR in 2023, and we look forward to continuing our work with you in the new year.

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Vol 13, No 10 (October, 2024)

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Expert Consensus

Systems mapping: a novel approach to national lung cancer screening implementation in Australia

Sandra Marjanovic, Andrew Page, Emily Stone, Danielle J. Currie, Nicole M. Rankin, Renelle Myers, Fraser Brims, Neal Navani, Kate A. McBride

PDF Pages: 2466-2478 Full Text (943) Peer Review File COI Form Open Access

Original Article

Adding immune checkpoint inhibitors to chemotherapy confers modest survival benefit in patients with small cell lung cancer and brain metastases: a retrospective analysis

Baishen Zhang, Jing Chen, Hui Yu, Meichen Li, Likun Chen

PDF Pages: 2479-2490 Full Text (434) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Exploring immunotherapy efficacy in non-small cell lung cancer patients with BRAF mutations: a case series and literature review

Izabela Chmielewska, Paweł Krawczyk, Magdalena Wójcik-Superczyńska, Anna Grenda, Michał Gil, Katarzyna Stencel, Robert Kieszko, Tomasz Jankowski, Janusz Milanowski

PDF Pages: 2491-2499 Full Text (495) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Efficacy and safety of radial probe endobronchial ultrasound-guided biopsy for peripheral lung lesions in chronic obstructive pulmonary disease patients

Young Seok Lee, Kyung Soo Hong, Jong Geol Jang, June Hong Ahn

PDF Pages: 2500-2510 Full Text (369) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Detailed characterization of combination treatment with MET inhibitor plus EGFR inhibitor in EGFR-mutant and MET-amplified non-small cell lung cancer

Youngjoo Lee, Seog-Yun Park, Geon Kook Lee, Hyun-Ju Lim, Yu-Ra Choi, Jaemin Kim, Ji-Youn Han

PDF Pages: 2511-2523 Full Text (470) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Exposure-lag response of surface net solar radiation on lung cancer incidence: a global time-series analysis

Xuanzhuang Lu, Runchen Wang, Jianfu Li, Shixuan Lyu, Jianrong Zhang, Qixia Wang, Wenhao Chi, Ran Zhong, Chao Chen, Xinjian Wu, Ruiyu Hu, Zhixuan You, Yuqi Mai, Songlin Xie, Jiayu Lin, Boyu Zheng, Qiu Zhong, Jianxing He, Wenhua Liang

PDF Pages: 2524-2537 Full Text (567) Reporting Checklist Peer Review File COI Form Open Access

Triple-targeted therapy of dabrafenib, trametinib, and osimertinib for the treatment of the acquired BRAF V600E mutation after progression on EGFR-tyrosine kinase inhibitors in advanced EGFR-mutated non-small cell lung cancer patients

Cheng-Di Weng, Ke-Jun Liu, Shi Jin, Jun-Wei Su, Yi-Hui Yao, Cheng-Zhi Zhou, Yu-Fa Li, Ze-Xin Chen, Hua-Jun Chen, Yan-Ying Li, Ke-Jing Tang, Jin-Ji Yang

PDF Pages: 2538-2548 Full Text (797) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Insights into sex differences in perioperative outcomes of non-small cell lung cancer patients

Quan Zheng, Jian Zhou, Yuanjin Zhang, Tengyong Wang, Dongsheng Wu, Qiang Pu, Jiandong Mei, Hu Liao, Lunxu Liu

PDF Pages: 2549-2560 Full Text (382) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Electromagnetic navigation bronchoscopy-guided preoperative lung nodule localization in video-assisted thoracic surgery (VATS): a learning curve analysis

Menghua Xue, Ke Lan, Xiaolong Yan, Tao Jiang, Xiaoping Wang, Feng Tian, Yunfeng Ni, Jinbo Zhao

PDF Pages: 2561-2572 Full Text (221) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Impact of docetaxel plus ramucirumab therapy on interstitial lung disease in recurrent advanced non-small cell lung cancer patients

Noriyuki Ebi, Hiroyuki Inoue, Yuta Fujimoto, Maiya Chen, Rei Sanai, Natsumi Kushima, Yusuke Osaki, Takato Ikeda, Akira Nakao, Yuki Shundo, Toyoshi Yanagihara, Naoki Hamada, Masaki Fujita

PDF Pages: 2573-2584 Full Text (509) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Predicting prognosis in patients with stage IA lung adenocarcinoma with a micropapillary component using a nomogram based on computed tomography radiomics and clinicopathologic factors: a retrospective analysis

Ying Li, Junfeng Zhao, Ruyue Li, Xiujing Yao, Xue Dong, Ying Zhao, Zhongshuo Xia, Yali Xu, Yintao Li

PDF Pages: 2585-2602 Full Text (433) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Prognostic significance of bone metastasis and clinical value of bone radiotherapy in metastatic non-small cell lung cancer receiving PD-1/PD-L1 inhibitors: results from a multicenter, prospective, observational study

Huiling Dong, Aihua Lan, Jie Gao, Yulin An, Li Chu, Xi Yang, Xiao Chu, Jie Hu, Qian Chu, Jianjiao Ni, Zhengfei Zhu

PDF Pages: 2603-2616 Full Text (481) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

A nomogram for predicting invasiveness of lung adenocarcinoma manifesting as ground-glass nodules based on follow-up CT imaging

Hanting Li, Qinyue Luo, Yuting Zheng, Chengyu Ding, Jinrong Yang, Leqing Chen, Xiaoqing Liu, Tingting Guo, Jun Fan, Xiaoyu Han, Heshui Shi

PDF Pages: 2617-2635 Full Text (278) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Inflammation, tertiary lymphoid structures, and lung cancer: a bibliometric analysis

Xiwen Liu, Huiting Liu, Linchong Huang, Lixuan Lin, Qi Cai, Yang Xiang, Zengfu Liu, Shuxin Zeng, Jianxing He, Wenhua Liang

PDF Pages: 2636-2648 Full Text (442) Peer Review File COI Form Open Access

Response to platinum-based therapies in second-line after immunotherapy in advanced or metastatic non-small-cell lung cancer PD-L1 ≥50%

Alejandro Olivares-Hernández, Luis Posado-Domínguez, Juan Carlos Redondo-González, Laura Corvo-Félix, Lorena Bellido Hernández, Emilio Fonseca-Sánchez, Edel del Barco-Morillo

PDF Pages: 2649-2659 Full Text (417) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

SWItch/Sucrose Nonfermentable complex-deficient pulmonary neoplasms: clinicopathologic characteristics and outcomes to radiotherapy and immunotherapy

Yu Gu, Songtao Lai, Juan Yang, Junhua Zhang, Xingwen Fan, Qiang Zheng

PDF Pages: 2660-2672 Full Text (471) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Phase II study of ramucirumab and docetaxel for previously platinum-treated patients with non-small cell lung cancer and malignant pleural effusion (PLEURAM study)

Shinnosuke Takemoto, Minoru Fukuda, Ryosuke Ogata, Hiroaki Senju, Nanae Sugasaki, Katsumi Nakatomi, Hiromi Tomono, Takayuki Suyama, Eisuke Sasaki, Midori Matsuo, Kazumasa Akagi, Fumiko Hayashi, Yosuke Dotsu, Sawana Ono, Noritaka Honda, Hirokazu Taniguchi, Hiroshi Gyotoku, Takaya Ikeda, Seiji Nagashima, Hiroshi Soda, Akitoshi Kinoshita, Hiroshi Mukae

PDF Pages: 2673-2682 Full Text (454) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Microbiota modulate immune repertories in lung adenocarcinoma via microbiota-immunity interactive network

Peng Liang, Qianxi Chen, Xiaoping Chen, Xiaolin Zhang, Yizhen Xiao, Guangni Liang, Ming Liu, Jianxing He, Wenhua Liang, Yufeng Liang, Bo Chen

PDF Pages: 2683-2697 Full Text (564) Reporting Checklist Peer Review File COI Form Open Access

Construction of a lung cancer 3D culture model based on alginate/gelatin micro-beads for drug evaluation

Ziying Zhao, Xiaoqing Feng, Huijuan Wu, Shuisheng Chen, Changsong Ma, Ziyun Guan, Luwen Lei, Kejing Tang, Xiao Chen, Yong Dong, Yubo Tang

PDF Pages: 2698-2712 Full Text (418) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Necroptosis-related lncRNAs: biomarkers for predicting prognosis and immune response in lung adenocarcinoma

Chunxuan Lin, Kunpeng Lin, Xiaochun Lin, Hai Yuan, Yingying Zhang, Zhijun Xie, Yong Dai, Luhao Liu, Yoshihisa Shimada, Taichiro Goto, Katsuhiro Okuda, Taisheng Liu, Chenggong Wei

PDF Pages: 2713-2728 Full Text (483) Reporting Checklist Peer Review File COI Form Open Access

Role of CENPL, DARS2, and PAICS in determining the prognosis of patients with lung adenocarcinoma

Rongjian Xu, Fengyi Han, Yandong Zhao, Ao Liu, Ning An, Baogang Wang, Patrick Zardo, José Sanz-Santos, Aimée J. P. M. Franssen, Erik R. de Loos, Min Zhao

PDF Pages: 2729-2745 Full Text (709) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

DeepGR: a deep-learning prognostic model based on glycolytic radiomics for non-small cell lung cancer

Tingting Fu, Peipei Yan, Lina Zhou, Zhihua Lu, Ao Liu, Xiao Ding, Jacopo Vannucci, Paul Hofman, Andrzej Swierniak, Edyta Szurowska, Junjun Zhang, Shicheng Li

PDF Pages: 2746-2760 Full Text (516) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

The time-to-surgery interval and its effect on pathological response after neoadjuvant chemoimmunotherapy in non-small cell lung cancer: a retrospective cohort study

Shuai-Dong Lin, Chang-Yong Tong, Dan-Dong Huang, Antonio Rossi, Hiroyuki Adachi, Miao Miao, Wen-Xin Zheng, Jing Guo

PDF Pages: 2761-2772 Full Text (318) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Blood biomarkers to predict the efficacy of neoadjuvant chemo-immunotherapy in non-small cell lung cancer patients

Yang Pan, Xuanhong Jin, Jiandong Hong, Yuxia Wang, Haoting Xu, Jingwei Lin, Yan Zhang, Kailai Yin, Jinhao Zhang, Kentaro Inamura, Dujiang Liu, Feng Li, Jian Zeng

PDF Pages: 2773-2786 Full Text (403) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Association of concomitant H1 antihistamine and immune checkpoint inhibitor therapy on survival outcome and safety in patients with advanced primary lung cancer: a cohort study

Wei-Hong Zhang, Bing-Xue Li, Chen-Xi Ma, Jian Wang, Fan Yang, Yan-Juan Xiong, Shu-Zhan Li, Jia-Li Zhang, Wei-Jiao Du, Zhen-Zhen Hui, Meng Shen, Li Zhou, Run-Mei Li, Xiao Tian, Ying Han, Bao-Zhu Ren, Yoshinobu Ichiki, Sang Chul Lee, Xin-Wei Zhang, Shui Cao, Xiu-Bao Ren, Liang Liu

PDF Pages: 2787-2801 Full Text (444) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Clinical, pathological, and computed tomography morphological features of lung cancer with spread through air spaces

Xiuming Zhang, Wei Qiao, Jiannan Shen, Qianlai Jiang, Chunhan Pan, Yunnong Wang, Joanna Bidzińska, Feng Dai, Lei Zhang

PDF Pages: 2802-2812 Full Text (316) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Review Article

What do we know about the role of neoadjuvant targeted therapy in early-stage EGFR-mutant and ALK-fused non-small cell lung cancer?—a narrative review of the current literature

Marcel Kemper, Sandra Elges, Peter Kies, Karsten Wiebe, Georg Lenz, Annalen Bleckmann, Georg Evers

PDF Pages: 2813-2827 Full Text (525) Reporting Checklist Peer Review File COI Form Open Access

Study Protocol

TQB2450 with or without anlotinib as maintenance treatment in subjects with locally advanced/unresectable non-small cell lung cancer that have not progressed after prior concurrent/sequential chemoradiotherapy (R-ALPS): study protocol for a randomized, double-blind, placebo-controlled, multicenter phase III trial

Baiqiang Dong, Long Chen, Qingsong Pang, Ou Jiang, Hong Ge, Yufeng Cheng, Rongrong Zhou, Xiangjiao Meng, Jie Li, Xuan Zhu, Xunqiang Wang, Qiuyue Cao, Yongling Ji, Ming Chen

PDF Pages: 2828-2837 Full Text (524) Reporting Checklist Peer Review File COI Form Open Access

Navigation of video-assisted thoracoscopic surgery using electromagnetic versus CT-guided localization (NOVEL): a study protocol for comparing procedural success and complication rates in a prospective, multicenter, randomized controlled, non-inferiority phase III trial

Juntao Xie, Dingpei Han, Yang Zhou, Boxuan Huang, Can Ge, Agathe Seguin-Givelet, Ajay Wagh, Yeon Wook Kim, Weicheng Kong, Censong Xu, Hecheng Li, Jie Zhang; the NOVEL study group

PDF Pages: 2838-2846 Full Text (275) Reporting Checklist Peer Review File COI Form Open Access

Case Report

Esophagomediastinal fistula during durvalumab plus tremelimumab with chemotherapy in angiotensin-converting enzyme 2-positive non-small cell lung cancer: a case report

Toshiyuki Sumi, Takumi Ikeda, Kotomi Arioka, Yuji Sakuma, Miki Yamaguchi, Taiki Ishigooka, Keigo Matsuura, Yuichi Yamada, Hirofumi Chiba

PDF Pages: 2847-2852 Full Text (801) Reporting Checklist Peer Review File COI Form Open Access

Editorial Commentary

Consolidation osimertinib for unresectable stage III epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer: redefining standard care

Fang Wu, Yue Zeng, Joel W. Neal

PDF Pages: 2853-2855 Full Text (399) Peer Review File COI Form Open Access

Predictive biomarkers for immune checkpoint efficacy: is multi-omics breaking the deadlock?

Alice Mogenet, Laurent Greillier, Pascale Tomasini

PDF Pages: 2856-2860 Full Text (163) Peer Review File COI Form Open Access

Erratum

Erratum to EGFR exon 20 insertion mutations and ERBB2 mutations in lung cancer: a narrative review on approved targeted therapies from oral kinase inhibitors to antibody-drug conjugates

Editorial Office

PDF Pages: 2861-2863 Full Text (184) Open Access

Review Articles

Management of ground-glass opacities: should all pulmonary lesions with ground-glass opacity be surgically resected?

Yoshihisa Kobayashi, Tetsuya Mitsudomi

Published online: 22 October 2013

PDF Pages: 354-363 Full Text (336040) Open Access

Editorial Commentary

Ground glass nodules with 5 years’ stability can grow after 10-year follow-up: do genetic features determine the fate?

Yoshihisa Kobayashi, Tetsuya Mitsudomi

Published online: 31 December 2019

PDF Pages: S425-S427 Full Text (74289) Open Access

Review Article

Non-small cell lung cancer: current treatment and future advances

Cecilia Zappa, Shaker A. Mousa

Published online: 30 June 2016

PDF Pages: 288-300 Full Text (70785) Open Access

Review Articles

Irreversible EGFR-TKIs: dreaming perfection

Lorenza Landi, Federico Cappuzzo

Published online: 14 January 2013

PDF Pages: 40-49 Full Text (69258) Open Access

Review Article

Pulmonary ground-glass opacity: computed tomography features, histopathology and molecular pathology

Jian-Wei Gao, Stefania Rizzo, Li-Hong Ma, Xiang-Yu Qiu, Arne Warth, Nobuhiko Seki, Mizue Hasegawa, Jia-Wei Zou, Qian Li, Marco Femia, Tang-Feng Lv, Yong Song, written on behalf of the AME Lung Cancer Collaborative Group

Published online: 28 February 2017

PDF Pages: 68-75 Full Text (53746) Open Access

Review Article

Recurrence after surgery in patients with NSCLC

Hidetaka Uramoto, Fumihiro Tanaka

Published online: 28 August 2014

PDF Pages: 242-249 Full Text (43244) Open Access

Review Article

Lung cancer prediction using machine learning and advanced imaging techniques

Timor Kadir, Fergus Gleeson

Published online: 14 June 2018

PDF Pages: 304-312 Full Text (41378) Open Access

Review Article

Targeted therapy for non-small cell lung cancer: current standards and the promise of the future

Bryan A. Chan, Brett G.M. Hughes

Published online: 24 February 2015

PDF Pages: 36-54 Full Text (41211) Open Access

Review Article

The past, present and future of immunotherapy against tumor

Tao Jiang, Caicun Zhou

Published online: 24 June 2015

PDF Pages: 253-264 Full Text (38935) Open Access

Review Article

Treatment of uncommon EGFR mutations in non-small cell lung cancer: new evidence and treatment

Tianli Zhang, Bing Wan, Yuan Zhao, Chuling Li, Hongbing Liu, Tangfeng Lv, Ping Zhan, Yong Song

Published online: 30 June 2019

PDF Pages: 302-316 Full Text (37717) Open Access

Review Article

Ground-glass nodules of the lung in never-smokers and smokers: clinical and genetic insights

Yoshihisa Kobayashi, Chiara Ambrogio, Tetsuya Mitsudomi

Published online: 28 August 2018

PDF Pages: 487-497 Full Text (33729) Chinese (3184) Open Access

Review Articles

KRAS mutant NSCLC, a new opportunity for the synthetic lethality therapeutic approach

Javier de Castro Carpeño, Cristóbal Belda-Iniesta

Published online: 03 April 2013

PDF Pages: 142-151 Full Text (31948) Open Access

Review Article

Molecular testing strategies in non-small cell lung cancer: optimizing the diagnostic journey

Jeffrey P. Gregg, Tianhong Li, Ken Y. Yoneda

Published online: 30 June 2019

PDF Pages: 286-301 Full Text (30784) Open Access

Review Article

The epidemiology of lung cancer

Patricia M. de Groot, Carol C. Wu, Brett W. Carter, Reginald F. Munden

Published online: 14 June 2018

PDF Pages: 220-233 Full Text (29987) Open Access

Review Article on Update on Pathology and Predictive Biomarkers of Lung Cancer

Biology of invasive mucinous adenocarcinoma of the lung

Yoon Jin Cha, Hyo Sup Shim

Published online: 11 October 2017

PDF Pages: 508-512 Full Text (29955) Open Access

Consensus

Tubeless video-assisted thoracic surgery for pulmonary ground-glass nodules: expert consensus and protocol (Guangzhou)

Jianxing He, Hengrui Liang, Wei Wang, Andrey Akopov, Alberto Aiolfi, Keng-Leong Ang, Luca Bertolaccini, Kaican Cai, Qingdong Cao, Baojun Chen, Chang Chen, Chun Chen, Donglai Chen, Fengxia Chen, Jun Chen, Lei Chen, Mingwu Chen, Yongbing Chen, Zhuxing Chen, Chao Cheng, Dong Cui, Fei Cui, Tianyang Dai, Qinglong Dong, Paolo A. Ferrari, Raja M. Flores, Junke Fu, Soichiro Funaki, Marios E. Froudarakis, Xiangfeng Gan, Mingfei Geng, Jialong Guo, Qiang Guo, Yongtao Han, Jintao He, Kaiming He, Kyoji Hirai, Jian Hu, Shuqiao Hu, Jian Huang, Jun Huang, Wenfa Jiang, Kyung Soo Kim, Gabor Kiss, Fanyi Kong, Lan Lan, Xuefeng Leng, Bin Li, Gaofeng Li, Hecheng Li, Hefei Li, Heng Li, Jiwei Li, Xiaoqiang Li, Shuben Li, Yinfen Li, Zhuoyi Li, Yi Liang, Lixia Liang, Wenhua Liang, Yongde Liao, Wanli Lin, Xu Lin, Hongxu Liu, Hui Liu, Jixian Liu, Jun Liu, Xiang Liu, Zihao Liu, Xingzhao Lu, Qingquan Luo, Naiquan Mao, Qi Pan, Dazhi Pang, Jun Peng, Jun Peng, Eugenio Pompeo, Rulin Qian, Kun Qiao, Bassam Redwan, Zi Sang, Wenlong Shao, Jianfei Shen, Weiyu Shen, Sook-Whan Sung, Wenfang Tang, Tianhu Wang, Guangsuo Wang, Haitao Wang, Huien Wang, Jiyong Wang, Wen Wang, Yongyong Wang, Zhenyuan Wang, Li Wei, Wei Wei, Hao Wu, Jie Wu, Zhaohua Xia, Chenyang Xu, Enwu Xu, Hai Xu, Ning Xu, Quan Xu, Rongyu Xu, Shun Xu, Chaokun Yang, Hanyu Yang, Shengli Yang, Jun Yi, Guangjian Zhang, Hao Zhang, Jia Zhang, Man Zhang, Xiao Zhang, Yajie Zhang, Zhe Zhang, Zhifeng Zhang, Honglin Zhao, Jian Zhao, Xiaodong Zhao, Jianping Zhou, Yanran Zhou, Chengchu Zhu, Shaojin Zhu, Xinhai Zhu, Jian Cui, Yubo Yan, Ke-Neng Chen

Published online: 28 August 2021

PDF Pages: 3503-3519 Full Text (28554) COI Form Open Access

Review Article

Lung cancer screening: nodule identification and characterization

Ioannis Vlahos, Konstantinos Stefanidis, Sarah Sheard, Arjun Nair, Charles Sayer, Joanne Moser

Published online: 14 June 2018

PDF Pages: 288-303 Full Text (28597) Open Access

Review Articles

New TNM classification: achievements and hurdles

Peter Goldstraw

Published online: 17 August 2013

PDF Pages: 264-272 Full Text (28539) Open Access

Review Article

Beyond ALK-RET, ROS1 and other oncogene fusions in lung cancer

Takashi Kohno, Takashi Nakaoku, Koji Tsuta, Katsuya Tsuchihara, Shingo Matsumoto, Kiyotaka Yoh, Koichi Goto

Published online: 19 April 2015

PDF Pages: 156-164 Full Text (27722) Open Access

Review Articles

Angiogenesis in cancer: anti-VEGF escape mechanisms

Gerald W. Prager, Marina Poettler, Matthias Unseld, Christoph C. Zielinski

Published online: 18 February 2012

PDF Pages: 14-25 Full Text (27553) Open Access

Full Most Read article list >>

Original Article

Prognostic value of Twist in lung cancer: systematic review and meta-analysis

Junli Zeng, Ping Zhan, Guannan Wu, Wen Yang, Wenjun Liang, Tangfeng Lv, Yong Song

BRAF mutations in non-small cell lung cancer

Peter P. Luk, Bing Yu, Chiu Chin Ng, Belinda Mercorella, Christina Selinger, Trina Lum, Steven Kao, Sandra A. O’Toole, Wendy A. Cooper

The suitability of small biopsy and cytology specimens for EGFR and other mutation testing in non-small cell lung cancer

Shu Wang, Bing Yu, Chiu Chin Ng, Belinda Mercorella, Christina I. Selinger, Sandra A. O’Toole, Wendy A. Cooper

Itraconazole can inhibit malignant pleural effusion by suppressing lymphangiogenesis in mice

Yunfen Wang, Yanwen Yao, Hongbin Liu, Xingqun Ma, Tangfeng Lv, Dongmei Yuan, Xinwu Xiao, Jie Yin, Yong Song

Ratio of maximum standardized uptake value to primary tumor size is a prognostic factor in patients with advanced non-small cell lung cancer

Fangfang Chen, Yanwen Yao, Chunyan Ma, Xingqun Ma, Zhaofeng Wang, Tangfeng Lv, Xinwu Xiao, Jie Yin, Yong Song

Advanced proton beam dosimetry part II: Monte Carlo vs. pencil beam-based planning for lung cancer

Dominic Maes, Jatinder Saini, Jing Zeng, Ramesh Rengan, Tony Wong, Stephen R. Bowen

The cytokinesis-blocked micronucleus assay as a novel biomarker for selection of lung cancer screening participants

Randa A. El-Zein, Carol J. Etzel, Reginald F. Munden

The use of TCP based EUD to rank and compare lung radiotherapy plans: in-silico study to evaluate the correlation between TCP with physical quality indices

Abdulhamid Chaikh, Jacques Balosso

Review Article

Beyond ALK-RET, ROS1 and other oncogene fusions in lung cancer

Takashi Kohno, Takashi Nakaoku, Koji Tsuta, Katsuya Tsuchihara, Shingo Matsumoto, Kiyotaka Yoh, Koichi Goto

Overview of clinicopathologic features of ALK-rearranged lung adenocarcinoma and current diagnostic testing for ALK rearrangement

Hyojin Kim, Jin-Haeng Chung

Neoadjuvant and adjuvant epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy for lung cancer

Haoran Zhai, Wenzhao Zhong, Xuening Yang, Yi-Long Wu

Known and putative mechanisms of resistance to EGFR targeted therapies in NSCLC patients with EGFR mutations—a review

Erin L. Stewart, Samuel Zhixing Tan, Geoffrey Liu, Ming-Sound Tsao

Clinical trials for lung cancer in China

Fei-Yu Niu, Wen-Zhao Zhong, Qing Zhou, Yi-Long Wu

Recurrence after surgery in patients with NSCLC

Hidetaka Uramoto, Fumihiro Tanaka

Prognostic markers in lung cancer: is it ready for prime time?

Chang-Qi Zhu, Ming-Sound Tsao

Potential biomarkers for lung cancer screening

Gabriella Sozzi, Mattia Boeri

Particle therapy in non-small cell lung cancer

Zhongxing Liao, Charles B. Simone II

Computer Aided Nodule Analysis and Risk Yield (CANARY) characterization of adenocarcinoma: radiologic biopsy, risk stratification and future directions

Ryan Clay, Srinivasan Rajagopalan, Ronald Karwoski, Fabien Maldonado, Tobias Peikert, Brian Bartholmai

Immunotherapy and radiation therapy for operable early stage and locally advanced non-small cell lung cancer

Neil K. Taunk, Andreas Rimner, Melissa Culligan, Joseph S. Friedberg, Julie Brahmer, Jamie Chaft

Combining immunotherapy and radiation therapy for small cell lung cancer and thymic tumors

Suchit H. Patel, Andreas Rimner, Roger B. Cohen

Intraoperative near-infrared imaging of mesothelioma

Gregory Thomas Kennedy, Andrew Newton, Jarrod Predina, Sunil Singhal

BAP1, a tumor suppressor gene driving malignant mesothelioma

Mitchell Cheung, Joseph R. Testa

Uncovering the immune tumor microenvironment in non-small cell lung cancer to understand response rates to checkpoint blockade and radiation

Jonathan E. Schoenhals, Steven N. Seyedin, Clark Anderson, Eric D. Brooks, Yun R. Li, Ahmed I. Younes, Sharareh Niknam, Ailin Li, Hampartsoum B. Barsoumian, Maria Angelica Cortez, James W. Welsh

Diagnostic and prognostic biomarkers for malignant mesothelioma: an update

Zhongjian Chen, Giovanni Gaudino, Harvey I. Pass, Michele Carbone, Haining Yang

Immunotherapy for malignant pleural mesothelioma: current status and future directions

Jordan Dozier, Hua Zheng, Prasad S. Adusumilli

Biology and clinical significance of circulating tumor cell subpopulations in lung cancer

Linda O’Flaherty, Harriet Wikman, Klaus Pantel

Routine clinical use of circulating tumor cells for diagnosis of mutations and chromosomal rearrangements in non-small cell lung cancer—ready for prime-time?

Emma Pailler, Vincent Faugeroux, Marianne Oulhen, Cyril Catelain, Françoise Farace

Challenges and unanswered questions for the next decade of circulating tumour cell research in lung cancer

Sumitra Mohan, Francesca Chemi, Ged Brady

Biophysical technologies for understanding circulating tumor cell biology and metastasis

Derrick W. Su, Jorge Nieva

Clinical utility of circulating tumor cells in patients with non-small-cell lung cancer

Marianna Gallo, Antonella De Luca, Monica Rosaria Maiello, Amelia D’Alessio, Claudia Esposito, Nicoletta Chicchinelli, Laura Forgione, Maria Carmela Piccirillo, Gaetano Rocco, Alessandro Morabito, Gerardo Botti, Nicola Normanno

Integrating immunotherapy into chemoradiation regimens for medically inoperable locally advanced non-small cell lung cancer

Salma K. Jabbour, Abigail T. Berman, Charles B. Simone II

Editorial

An alternative way to initiate Notch1 signaling in non-small cell lung cancer

Yi-Lin Yang, David Jablons, Liang You

Combination MET- and EGFR-directed therapy in MET-overexpressing non-small cell lung cancers: time to move on to better biomarkers?

Fernando C. Santini, Siddharth Kunte, Alexander Drilon

Systematic Review and Meta-analysis

Association of the metformin with the risk of lung cancer: a meta-analysis

Li Wang, Yong Song, Guan-Nan Wu, Dong-Mei Yuan

China Lung Cancer Research Highlight

Dll4/Notch1 signaling from tip/stalk endothelial cell specification to stroma-dependent lung tumor inhibition: a flavor of Dll4/Notch1 pleiotropy in tumor cell biology

Maria Felice Brizzi, Paola Defilippi

Editorials

Dulanermin in cancer therapy: Still much to do

Cristina Quintavalle, Gerolama Condorelli

Review Articles

EGFR molecular testing in African-American non-small cell lung cancer patients - a review of discrepant data

Bradley T. Clifford, Pingfu Fu, Nathan A. Pennell, Balazs Halmos, Rom S. Leidner

Copy number gains of FGFR1 and 3q chromosome in squamous cell carcinoma of the lung

Pedro Mendez, Jose Luis Ramirez

Role of HGF/MET axis in resistance of lung cancer to contemporary management

Kanwal Pratap Singh Raghav, Ana Maria Gonzalez-Angulo, George R. Blumenschein Jr

Circulating soluble intercellular adhesion Molecule-1 in lung cancer: a systematic review

Xiaoling Gu, Chunyan Ma, Dongmei Yuan, Yong Song

Ceritinib

Clinical development and approval of second generation ALK inhibitors for ALK rearranged lung cancer

Daniel B. Costa

Onartuzumab plus erlotinib

Targeting MET in NSCLC: looking for a needle in a haystack

Lorenza Landi, Federico Cappuzzo

Nivolumab

Nivolumab (anti-PD-1, BMS-936558, ONO-4538) in patients with advanced non-small cell lung cancer

Arun Rajan, James L. Gulley

Brief Report

The role of Imaging and Radiation Oncology Core for precision medicine era of clinical trial

Ying Xiao, Mark Rosen

Review Article on Update on Pathology and Predictive Biomarkers of Lung Cancer

Biology of invasive mucinous adenocarcinoma of the lung

Yoon Jin Cha, Hyo Sup Shim

Immunohistochemistry for predictive biomarkers in non-small cell lung cancer

Mari Mino- Kenudson

Below are the latest Translational Lung Cancer Research articles published online ahead of print publication.

Original Article

Phase Ib/II study of imprime PGG and pembrolizumab in patients with previously treated advanced non-small cell lung cancer (NSCLC): BTCRC LUN 15-017

Muhammad Furqan, Jyoti Malhotra, Ardaman Shergill, Li Liu, Sarah L. Mott, Mary M. Pasquinelli, Alicia Hulbert, Kathleen Kennedy, Lawrence Feldman

Published online: 19 November 2024

Original Article

Lung autotransplantation for advanced central lung cancer after neoadjuvant immuno-chemotherapy: a case series study

Yongjiang Chen, Rui Wang, Dong Lin, Hui Pan, Chao Yang, Hongxu Liu, Wei Huang, Jiang Fan, Shuben Li

Published online: 18 November 2024

Original Article

Optimizing epidermal growth factor receptor-tyrosine kinase inhibitor treatment in lung cancer: a systematic review and meta-analysis of the influence of gastric acid suppressants

Beong Ki Kim, Ye Seul Seong, Se Hyun Kwak, Eun Hye Lee, Sang Hoon Lee, Eun Young Kim, Yoon Soo Chang, Chi Young Kim

Published online: 18 November 2024

Original Article

Construction of a risk prediction model for isolated pulmonary nodules 5–15 mm in diameter

Siting Xie, Xingguang Luo, Yuxin Guo, Xiulian Huang, Jinyu Long, Ying Chen, Ping Lin, Jinhe Xu, Shangwen Xu, Chunlei Zhao, Baoquan Lin, Chunxia Su, Nagarashee Seetharamu, Duilio Divisi, Mingliang Jin, Zongyang Yu

Published online: 14 November 2024

Original Article

Prognostic impact of targetable driver alterations in resected early-stage lung cancer

Angelika Terbuch, Selma Konjic, Verena Schlintl, Gudrun Absenger, Philipp J. Jost, Jörg Lindenmann, Paul Swatek, Nikolaus John, Teresa John, Robert Wurm, Martin Zacharias, Florian Posch, Maximilian J. Hochmair, Hannah Fabikan, Christoph Weinlinger, Oliver Illini, Lena Horvath, Gabriele Gamerith, Dominik Wolf, Florian Augustin, Luka Brcic

Published online: 14 November 2024

Original Article

The potential high-risk population for lung cancer screening: determination of initial screening age and heterogeneity in histology and sex

Keyi Chen, Yanze Yin, Chao Wang, Ao Zeng, Xinyun Fang, Abudumijiti Abuduwayiti, Zhilong Xu, Jie Dai, Gening Jiang

Published online: 13 November 2024

Case Report

Invasive mucinous adenocarcinoma harbored MET exon 14 skipping mutation: case report

Atsushi Washioka, Hiroaki Akamatsu, Takeya Sugimoto, Daiki Kitahara, Takahiro Kaki, Eriko Murakami, Atsushi Hayata, Ryuta Iwamoto, Nobuyuki Yamamoto

Published online: 12 November 2024

Original Article

Mutational differences between primary cancer tissue and circulating tumor cells in early-stage non-small cell lung cancer

Woojung Kim, Sukki Cho, Joonseok Lee, Jinsu Lee, Soojeong Ji, Hyejin Sung, Woohyun Jung, Jae Hyun Jeon, Kwhanmien Kim, Sanghoon Jheon

Published online: 12 November 2024

Editorial Commentary

Epidermal growth factor receptor exon 20 insertion mutations: are we getting closer to solving the puzzle?

Thomas E. Stinchcombe

Published online: 12 November 2024

Original Article

Treatment of metastatic ALK-positive non-small cell lung cancer: real-world outcomes in a single center study

Caroline Kamali, Georgios Tsakonas, Per Hydbring, Kenbugul Jatta, Anders Berglund, Kristina Viktorsson, Rolf Lewensohn, Luigi De Petris, Simon Ekman

Published online: 12 November 2024

Original Article

Comparing the outcomes of MR-based versus CT-based tumor delineation in locally advanced non-small cell lung cancer treated with hypo-fractionated radiotherapy and concurrent chemotherapy

Pengxin Zhang, Shouliang Ding, Kangqiang Peng, Haoqiang He, Daquan Wang, Rui Zhou, Bin Wang, Jinyu Guo, Hongdong Liu, Xiaoyan Huang, Chuanmiao Xie, Hui Liu, Bo Qiu

Published online: 06 November 2024

Original Article

Altered carnitine transporter genes (SLC22A5, SLC22A16, SLC6A14) expression pattern among lung cancer patients

Konrad Kędzia, Dagmara Szmajda-Krygier, Adrian Krygier, Sławomir Jabłoński, Ewa Balcerczak, Szymon Wcisło

Published online: 05 November 2024

Journal Highlight more

Translational Lung Cancer Research is an international, peer-reviewed, open-access journal indexed by Science Citation Index Expanded (SCIE) and PubMed/PubMed Central, focusing on cutting-edge development on the transition from preclinical to clinical research, including but not limited to multimodality therapy, markers, imaging, tumor biology, pathology, chemoprevention, and technical advances related to lung cancer and relevant thoracic diseases.