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Join us at the 33rd Annual Meeting of the European Society of Thoracic Surgery (ESTS)

The 33rd Annual Meeting of the European Society of Thoracic Surgery is going to be held in May 25-27, 2025 in Budapest, Hungary: https://estsmeeting.com.

This time, Translational Lung Cancer Research (TLCR) as well as its sister journals and books published by AME Publishing Company will be on display during this exciting academic event! We would like to seize this great opportunity to meet our authors, editorial board members and readers.

Interviews with Outstanding Authors (2025)

In 2025, many authors make outstanding contributions to our journal. Their articles published with us have received very well feedback in the field and stimulate a lot of discussions and new insights among the peers.

Hereby, we would like to highlight some of our outstanding authors, with a brief interview of their thoughts and insights as authors. Allow us to express our heartfelt gratitude for their tremendous effort and valuable contributions to the scientific process.

Reviewer of the Month (2025)

In 2025, TLCR reviewers continue to make outstanding contributions to the peer review process. They demonstrated professional effort and enthusiasm in their reviews and provided comments that genuinely help the authors to enhance their work.

Hereby, we would like to highlight some of our outstanding reviewers, with a brief interview of their thoughts and insights as a reviewer. Allow us to express our heartfelt gratitude for their tremendous effort and valuable contributions to the scientific process.

Join us at the 105th Annual Meeting of American Association for Thoracic Surgery (AATS)

The 105th Annual Meeting of American Association for Thoracic Surgery (AATS) is going to be held at the Seattle Convention Center, Seattle, WA, USA from May 2 to 5, 2025: https://events.aats.org/am25.

As the world's most prestigious thoracic surgery event, the annual meeting of AATS helps grow one’s expertise, network with leading experts, and build the future of thoracic surgery.

This year Translational Lung Cancer Research (TLCR) as well as its sister journals and books published by AME Publishing Company will be on display during this exciting academic event! We would like to seize this great opportunity to meet our authors, editorial board members and readers.

TLCR Annual Report 2024

Welcome to the 2024 annual report for Translational Lung Cancer Research. In 2024, the TLCR has continued its mission to increase the quality and impact of the journal, and to provide readers with a novel, well-organized, informative, enlightening and educational journal.

We would like to sincerely thank our Editorial Board Members, Guest editors, Reviewers, Authors, Readers for all your supports and contributions to TLCR in 2024, and we look forward to continuing our work with you in the new year.

Interviews with Editorial Board Members

TLCR features a distinguished editorial board, the members of which continue to instill the power of their expertise for the journal’s development. By launching this column, we are glad to introduce to you some of them in the form of interviews, in which they will share their unique career experiences and perspectives. We believe their insights will shed light on the knowledge of related fields.

Interviews with Guest Editors

Over the years, a number of TLCR guest editors have made valuable contributions to the journal. This column features interviews with our guest editors, who graciously share their experience in scientific careers and provide insightful perspectives on the special series.

New Impact Factor for Translational Lung Cancer Research: 4

We are pleased to announce that the Translational Lung Cancer Research (TLCR) has attained its latest impact factor update for the 2023 citation year: 4.

Translational Lung Cancer Research 2023 CiteScore Released: 7.2

We are pleased to announce that the Translational Lung Cancer Research (TLCR) has received its 2023 CiteScore: 7.2, ranking 92 out of 404 journals in the Oncology category.

Furthermore, we are delighted to highlight the remarkable achievements made by all AME journals in the CiteScore ranking.

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Vol 14, No 2 (February, 2025)

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Editorial Commentary

Light on the horizon for HER2 overexpressing non-small cell lung cancer?

Kira-Lee Koster, Martin Früh

PDF Pages: 305-309 Full Text (261) Peer Review File COI Form Open Access

Alectinib impressively enters the adjuvant setting for early-stage ALK-rearranged non-small cell lung cancer and outperforms chemotherapy—let’s define who benefits the most

Eric Santoni-Rugiu, Jens Benn Sørensen, Edyta Maria Urbanska

PDF Pages: 310-313 Full Text (240) Peer Review File COI Form Open Access

Trastuzumab deruxtecan in HER2 overexpressing non-small cell lung cancer (NSCLC)

Omali Pitiyarachchi, Aaron C. Tan

PDF Pages: 314-322 Full Text (272) Peer Review File COI Form Open Access

Will “Sun”-WUKONG, the monkey king, conquer EGFR exon 20 insertion mutation positive non-small cell lung cancer?

Molly Li, Ross A. Soo

PDF Pages: 323-327 Full Text (216) Peer Review File COI Form Open Access

Novel immune checkpoint inhibitor strategies in advanced non-small cell lung cancer: towards biomarker-driven therapies?

M. Benthe Muntinghe-Wagenaar, T. Jeroen N. Hiltermann

PDF Pages: 328-333 Full Text (230) Peer Review File COI Form Open Access

Sunvozertinib: shining light on lung cancer’s exon 20 fight

Tetsuya Mitsudomi

PDF Pages: 334-340 Full Text (213) Peer Review File COI Form Open Access

Original Article

Study of the radiologic and pathologic correlations for subsolid lung adenocarcinoma with the application of whole-mount sections (ECTOP1011)

Ting Ye, Xuxia Shen, Shengping Wang, Haoxuan Wu, Yue Wang, Hong Hu, Yang Zhang, Qingyuan Huang, Zezhou Wang, Yajia Gu, Yuan Li, Haiquan Chen

PDF Pages: 341-352 Full Text (277) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Rapid detection of non-small cell lung cancer driver mutations using droplet digital polymerase chain reaction analysis of bronchial washings: a prospective multicenter study

Kohei Somekawa, Nobuaki Kobayashi, Satoshi Nagaoka, Kenichi Seki, Yukihito Kajita, Suguru Muraoka, Ami Izawa, Ayami Kaneko, Yukiko Otsu, Momo Hirata, Sousuke Kubo, Ryo Nagasawa, Kota Murohashi, Hiroaki Fuji, Shuhei Teranishi, Ken Tashiro, Keisuke Watanabe, Nobuyuki Horita, Yu Hara, Makoto Kudo, Takeshi Kaneko

PDF Pages: 353-362 Full Text (258) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Comparison of metastasis and treatment patterns among different histopathologic types of lung cancer: analysis of 6 years of nationwide lung cancer cohort data in Korea

Jeong Uk Lim, Kyu Yean Kim, Ho Cheol Kim, Tae-Jung Kim, Hong Kwan Kim, Mi Hyoung Moon, Kyongmin Sarah Beck, Yang Gun Suh, Chang Hoon Song, Jin Seok Ahn, Jeong Eun Lee, Jae Hyun Jeon, Chi Young Jung, Jeong Su Cho, Yoo Duk Choi, Seung Sik Hwang, Young Sik Park, Soon Ho Yoon, Joon Young Choi, Chang-Min Choi, Seung Hun Jang; Korean Association for Lung Cancer; Korea Central Cancer Registry

PDF Pages: 363-384 Full Text (241) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Dual-layer spectral detector computed tomography multiparameter machine learning model for prediction of invasive lung adenocarcinoma

Jiayu Wan, Xue Lin, Zhaokai Wang, Peng Sun, Shen Gui, Tianhe Ye, Qianqian Fan, Weiwei Liu, Feng Pan, Bo Yang, Xiaotong Geng, Zhen Quan, Lian Yang

PDF Pages: 385-397 Full Text (305) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Predictive value of perioperative carcinoembryonic antigen changes for recurrence in non-small cell lung cancer

Hua Sun, Sikai Wu, Zhongxiao Chen, Hao Liu, William C. Cho, Pasan Witharana, Minhua Ye, Dehua Ma, Chunguo Wang, Chengchu Zhu, Jianfei Shen

PDF Pages: 398-407 Full Text (223) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Sleeve lobectomy versus lobectomy after neoadjuvant chemo-immunotherapy for non-small cell lung cancer invading the lobar bronchial orifice: a multicenter retrospective cohort study

Tianyue Ma, Jun Yi, Yong Ge, Haitang Yang, Jiayi Wang, Shuyuan Li, Ran Ma, Guodong Zhang, Hao Peng, Pingping Song, Feng Yao, Hao Zhang

PDF Pages: 408-421 Full Text (211) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Immunotherapy efficacy between exon 19 deletion and exon 21 L858R mutation in advanced EGFR mutant non-small-cell lung cancer: a direct and indirect meta-analysis

Zihong Chen, Lanlan Pang, Yuwen Yang, Xinyi He, Jianhua Zhan, Lin Zhang, Kangqiao Xiong, Wenfeng Fang, Li Zhang, Yaxiong Zhang

PDF Pages: 422-430 Full Text (251) Reporting Checklist Peer Review File COI Form Open Access

Spectral dual-layer detector CT-based radiomics-deep learning for predicting pathological aggressiveness of stage I lung adenocarcinoma: discrimination of precursor glandular lesions and invasive adenocarcinomas

Tong Wang, Zheng Fan, Yong Yue, Xiaomei Lu, Xiaoxu Deng, Yang Hou

PDF Pages: 431-448 Full Text (221) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Whole-section digital analysis of immune profiles in surgically resected small cell lung carcinoma and their associations with molecular subtypes

Yanli Zhu, Jianghua Wu, Haiyue Wang, Kaiwen Chi, Xinting Diao, Minglei Zhuo, Dongmei Lin

PDF Pages: 449-466 Full Text (183) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Real-world comparison of neoadjuvant pembrolizumab plus chemotherapy versus tislelizumab plus chemotherapy in patients with resectable non-small cell lung cancer: a retrospective cohort study of treatment outcomes

Yan Hu, Siying Ren, Juan Feng, Chao Zeng, Lulu Yang, Jinyou Liu, Fang Wu, Wenliang Liu

PDF Pages: 467-479 Full Text (276) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Dual-phase computed tomography imaging for lung function assessment in patients with early-stage non-small cell lung cancer

Yizhen Jia, Qinmin Hao, Fen Wang, Jun Wang, Liang Chen, Mei Yuan

PDF Pages: 480-490 Full Text (243) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Aspirin impedes non-small cell lung cancer development via fine-tuning the CD36 localization regulated by GPIHBP1

Wei Liu, Dujuan Qiao, Jia Chen, Ya Gao, Katsuhiro Okuda, Yoshihisa Shimada, Linong Yao

PDF Pages: 491-512 Full Text (247) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Clinical application of three-dimensional reconstruction in anatomical analysis of the right anterior, lateral, and posterior basal segments (RS8, RS9, and RS10) for RS9 segmentectomy

Jiafu Zhu, Sui Chen, Yukang Lin, Jiangshan Huang, Marcus Taylor, Junji Ichinose, Yeon Wook Kim, Zihao Zheng, Jinyang Shi, Litao Yang, Jiangbo Lin

PDF Pages: 513-525 Full Text (189) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Clinical-genomic nomogram for predicting sensitivity to second-line immunotherapy for advanced non-small cell lung cancer

Ying Hua, Ai Wang, Chao Xie, Apostolos C. Agrafiotis, Pinlang Zhang, Baosheng Li

PDF Pages: 526-537 Full Text (236) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Efficacy of neoadjuvant immunochemotherapy in the treatment of stage III non-small-cell lung cancer with cancer driver gene mutations

Yuhong Yang, Jiacong Liu, Linhai Zhu, Xuhua Huang, Jiayue Ye, Nagashree Seetharamu, Hiroyuki Adachi, Jinming Xu, Yiqing Wang, Pinghui Xia, Wang Lv, Chong Zhang, Jian Hu

PDF Pages: 538-551 Full Text (195) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Risk factors for postoperative pulmonary complications in non-adenocarcinoma non-small cell lung cancer patients undergoing surgery after neoadjuvant therapy

Hu Zhang, Xiaowei Mao, Jingwei Xu, Lijiang Song, Zhengwei Huang, Yao Li, Jiajing Sun, Jiali Qian, Shan Xu, Fabrizio Minervini, Kentaro Inamura, Zhengfu He

PDF Pages: 552-562 Full Text (288) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Comparative outcomes of first-line PD-1/PD-L1 inhibitors plus chemotherapy for advanced squamous non-small cell lung cancer: a systematic review and network meta-analysis of randomized clinical trials

Zhefeng Liu, Zhikuan Wang, Jun Zhu, Haitao Tao, Ziwei Huang, Lu Han, Akshay J. Patel, Yi Hu

PDF Pages: 563-574 Full Text (364) Reporting Checklist Peer Review File COI Form Open Access

Review Article

Lung cancer organoids: a new strategy for precision medicine research

Yuan Meng, Xinyi Shu, Jie Yang, Yangyueying Liang, Meiying Zhu, Xuerui Wang, Yue Li, Fanming Kong

PDF Pages: 575-590 Full Text (303) Peer Review File COI Form Open Access

Radiotherapy as salvage therapy and an adjunct to immunotherapy: exploring local and abscopal mechanisms to overcome immunotherapy resistance: a narrative review

Yunxin Yang, Tong Liu, Song Mi, Xin Liu, Salma K. Jabbour, Ning Liang, Guodong Deng, Pingping Hu, Jiandong Zhang

PDF Pages: 591-606 Full Text (241) Reporting Checklist Peer Review File COI Form Open Access

Case Report | iMDT Corner

Cerebrospinal fluid cytology for the diagnosis of lung cancer brain metastasis: a case report

Lidan Xing, Jiajia Liu, Haiyang Yan, Jing Chen, Lingling Gao, Muhammad Zubair Afzal, Toyoaki Hida, Shuai Zhao, Jingna Sun

PDF Pages: 607-613 Full Text (170) Reporting Checklist Peer Review File COI Form Open Access

Case Report

Pathologic complete response following salvage surgery after lazertinib treatment in advanced EGFR-mutated lung adenocarcinoma: case report and literature review

Chanmi Kim, Jongsoo Park, Jang Hoon Lee, Seong Yong Jeong, June Hong Ahn

PDF Pages: 614-618 Full Text (237) Reporting Checklist Peer Review File COI Form Open Access

Ion robotic bronchoscopy laser ablation and Da Vinci robotic segmentectomy for bilateral pulmonary nodules: a case report

Teng Sun, Yong Ge, Zhiqiao Chen, Tianyue Ma, Shoujie Feng, Hao Zhang

PDF Pages: 619-624 Full Text (171) Reporting Checklist Peer Review File COI Form Open Access

Novel LZTR1 germline mutation as a mechanism of resistance to osimertinib in EGFR-mutated lung adenocarcinoma: a case report

Wai Park, Jeremy Fricke, Isa Mambetsariev, Giovanny Velasquez, Reza Nadaf-Rahrov, Shaira Therese Dingal, Pauline Kim, Razmig Babikian, Arya Amini, Michelle Afkhami, Ravi Salgia

PDF Pages: 625-630 Full Text (211) Reporting Checklist Peer Review File COI Form Open Access

Partial response to lorlatinib in thoracic inflammatory myofibroblastic tumor harboring complex and rare ALK fusions: a case report

Li-Bo Tang, Ying-Long Peng, Xiao-Rong Yang, Jia-Ting Li, Chang Lu, Mei-Mei Zheng, Lu Sun, Zheng Yang, Li-Xu Yan, Yu Deng, Zhi-Hong Chen, Si-Di Lv, Qing Zhou, Chong-Rui Xu

PDF Pages: 631-638 Full Text (191) Reporting Checklist Peer Review File COI Form Open Access

Unravelling the complexity of EGFR-mutated lung adenocarcinoma: a unique case report with histological transformations and co-alteration acquisition

Anissa Boutahir, Véronique Dalstein, Jean Baptiste Oudart, Gaëtan Deslee, Chistine Clavel, Maxime Dewolf, Anne Durlach, Julien Ancel

PDF Pages: 639-648 Full Text (207) Reporting Checklist Peer Review File COI Form Open Access

Letter to the Editor

Learning from chronic disease screening success: developing efficient, convenient, and affordable lung cancer screening methods to achieve universal coverage

Jianxing He, Wenhua Liang, Nanshan Zhong

PDF Pages: 649-651 Full Text (190) Peer Review File COI Form Open Access

Erratum

Erratum: Tumor cavitation in patients with non-small-cell lung cancer receiving anti-angiogenic therapy with apatinib

Editorial Office

PDF Pages: 652 Full Text (123) Open Access

Review Articles

Management of ground-glass opacities: should all pulmonary lesions with ground-glass opacity be surgically resected?

Yoshihisa Kobayashi, Tetsuya Mitsudomi

Published online: 22 October 2013

PDF Pages: 354-363 Full Text (338456) Open Access

Editorial Commentary

Ground glass nodules with 5 years’ stability can grow after 10-year follow-up: do genetic features determine the fate?

Yoshihisa Kobayashi, Tetsuya Mitsudomi

Published online: 31 December 2019

PDF Pages: S425-S427 Full Text (82007) Open Access

Review Article

Non-small cell lung cancer: current treatment and future advances

Cecilia Zappa, Shaker A. Mousa

Published online: 30 June 2016

PDF Pages: 288-300 Full Text (77137) Open Access

Review Articles

Irreversible EGFR-TKIs: dreaming perfection

Lorenza Landi, Federico Cappuzzo

Published online: 14 January 2013

PDF Pages: 40-49 Full Text (70133) Open Access

Review Article

Pulmonary ground-glass opacity: computed tomography features, histopathology and molecular pathology

Jian-Wei Gao, Stefania Rizzo, Li-Hong Ma, Xiang-Yu Qiu, Arne Warth, Nobuhiko Seki, Mizue Hasegawa, Jia-Wei Zou, Qian Li, Marco Femia, Tang-Feng Lv, Yong Song, written on behalf of the AME Lung Cancer Collaborative Group

Published online: 28 February 2017

PDF Pages: 68-75 Full Text (59109) Open Access

Review Article

Recurrence after surgery in patients with NSCLC

Hidetaka Uramoto, Fumihiro Tanaka

Published online: 28 August 2014

PDF Pages: 242-249 Full Text (46841) Open Access

Review Article

Targeted therapy for non-small cell lung cancer: current standards and the promise of the future

Bryan A. Chan, Brett G.M. Hughes

Published online: 24 February 2015

PDF Pages: 36-54 Full Text (42962) Open Access

Review Article

Lung cancer prediction using machine learning and advanced imaging techniques

Timor Kadir, Fergus Gleeson

Published online: 14 June 2018

PDF Pages: 304-312 Full Text (42693) Open Access

Review Article

Treatment of uncommon EGFR mutations in non-small cell lung cancer: new evidence and treatment

Tianli Zhang, Bing Wan, Yuan Zhao, Chuling Li, Hongbing Liu, Tangfeng Lv, Ping Zhan, Yong Song

Published online: 30 June 2019

PDF Pages: 302-316 Full Text (42063) Open Access

Review Article

The past, present and future of immunotherapy against tumor

Tao Jiang, Caicun Zhou

Published online: 24 June 2015

PDF Pages: 253-264 Full Text (39418) Open Access

Review Article

Ground-glass nodules of the lung in never-smokers and smokers: clinical and genetic insights

Yoshihisa Kobayashi, Chiara Ambrogio, Tetsuya Mitsudomi

Published online: 28 August 2018

PDF Pages: 487-497 Full Text (36583) Chinese (5205) Open Access

Review Article

The epidemiology of lung cancer

Patricia M. de Groot, Carol C. Wu, Brett W. Carter, Reginald F. Munden

Published online: 14 June 2018

PDF Pages: 220-233 Full Text (33511) Open Access

Review Article

Lung cancer screening: nodule identification and characterization

Ioannis Vlahos, Konstantinos Stefanidis, Sarah Sheard, Arjun Nair, Charles Sayer, Joanne Moser

Published online: 14 June 2018

PDF Pages: 288-303 Full Text (32638) Open Access

Review Articles

KRAS mutant NSCLC, a new opportunity for the synthetic lethality therapeutic approach

Javier de Castro Carpeño, Cristóbal Belda-Iniesta

Published online: 03 April 2013

PDF Pages: 142-151 Full Text (32362) Open Access

Review Article

Molecular testing strategies in non-small cell lung cancer: optimizing the diagnostic journey

Jeffrey P. Gregg, Tianhong Li, Ken Y. Yoneda

Published online: 30 June 2019

PDF Pages: 286-301 Full Text (31922) Open Access

Review Article on Update on Pathology and Predictive Biomarkers of Lung Cancer

Biology of invasive mucinous adenocarcinoma of the lung

Yoon Jin Cha, Hyo Sup Shim

Published online: 11 October 2017

PDF Pages: 508-512 Full Text (31768) Open Access

Consensus

Tubeless video-assisted thoracic surgery for pulmonary ground-glass nodules: expert consensus and protocol (Guangzhou)

Jianxing He, Hengrui Liang, Wei Wang, Andrey Akopov, Alberto Aiolfi, Keng-Leong Ang, Luca Bertolaccini, Kaican Cai, Qingdong Cao, Baojun Chen, Chang Chen, Chun Chen, Donglai Chen, Fengxia Chen, Jun Chen, Lei Chen, Mingwu Chen, Yongbing Chen, Zhuxing Chen, Chao Cheng, Dong Cui, Fei Cui, Tianyang Dai, Qinglong Dong, Paolo A. Ferrari, Raja M. Flores, Junke Fu, Soichiro Funaki, Marios E. Froudarakis, Xiangfeng Gan, Mingfei Geng, Jialong Guo, Qiang Guo, Yongtao Han, Jintao He, Kaiming He, Kyoji Hirai, Jian Hu, Shuqiao Hu, Jian Huang, Jun Huang, Wenfa Jiang, Kyung Soo Kim, Gabor Kiss, Fanyi Kong, Lan Lan, Xuefeng Leng, Bin Li, Gaofeng Li, Hecheng Li, Hefei Li, Heng Li, Jiwei Li, Xiaoqiang Li, Shuben Li, Yinfen Li, Zhuoyi Li, Yi Liang, Lixia Liang, Wenhua Liang, Yongde Liao, Wanli Lin, Xu Lin, Hongxu Liu, Hui Liu, Jixian Liu, Jun Liu, Xiang Liu, Zihao Liu, Xingzhao Lu, Qingquan Luo, Naiquan Mao, Qi Pan, Dazhi Pang, Jun Peng, Jun Peng, Eugenio Pompeo, Rulin Qian, Kun Qiao, Bassam Redwan, Zi Sang, Wenlong Shao, Jianfei Shen, Weiyu Shen, Sook-Whan Sung, Wenfang Tang, Tianhu Wang, Guangsuo Wang, Haitao Wang, Huien Wang, Jiyong Wang, Wen Wang, Yongyong Wang, Zhenyuan Wang, Li Wei, Wei Wei, Hao Wu, Jie Wu, Zhaohua Xia, Chenyang Xu, Enwu Xu, Hai Xu, Ning Xu, Quan Xu, Rongyu Xu, Shun Xu, Chaokun Yang, Hanyu Yang, Shengli Yang, Jun Yi, Guangjian Zhang, Hao Zhang, Jia Zhang, Man Zhang, Xiao Zhang, Yajie Zhang, Zhe Zhang, Zhifeng Zhang, Honglin Zhao, Jian Zhao, Xiaodong Zhao, Jianping Zhou, Yanran Zhou, Chengchu Zhu, Shaojin Zhu, Xinhai Zhu, Jian Cui, Yubo Yan, Ke-Neng Chen

Published online: 28 August 2021

PDF Pages: 3503-3519 Full Text (30068) COI Form Open Access

Review Article

Beyond ALK-RET, ROS1 and other oncogene fusions in lung cancer

Takashi Kohno, Takashi Nakaoku, Koji Tsuta, Katsuya Tsuchihara, Shingo Matsumoto, Kiyotaka Yoh, Koichi Goto

Published online: 19 April 2015

PDF Pages: 156-164 Full Text (29104) Open Access

Review Articles

New TNM classification: achievements and hurdles

Peter Goldstraw

Published online: 17 August 2013

PDF Pages: 264-272 Full Text (28899) Open Access

Review Articles

Angiogenesis in cancer: anti-VEGF escape mechanisms

Gerald W. Prager, Marina Poettler, Matthias Unseld, Christoph C. Zielinski

Published online: 18 February 2012

PDF Pages: 14-25 Full Text (28708) Open Access

Full Most Read article list >>

Original Article

Prognostic value of Twist in lung cancer: systematic review and meta-analysis

Junli Zeng, Ping Zhan, Guannan Wu, Wen Yang, Wenjun Liang, Tangfeng Lv, Yong Song

BRAF mutations in non-small cell lung cancer

Peter P. Luk, Bing Yu, Chiu Chin Ng, Belinda Mercorella, Christina Selinger, Trina Lum, Steven Kao, Sandra A. O’Toole, Wendy A. Cooper

The suitability of small biopsy and cytology specimens for EGFR and other mutation testing in non-small cell lung cancer

Shu Wang, Bing Yu, Chiu Chin Ng, Belinda Mercorella, Christina I. Selinger, Sandra A. O’Toole, Wendy A. Cooper

Itraconazole can inhibit malignant pleural effusion by suppressing lymphangiogenesis in mice

Yunfen Wang, Yanwen Yao, Hongbin Liu, Xingqun Ma, Tangfeng Lv, Dongmei Yuan, Xinwu Xiao, Jie Yin, Yong Song

Ratio of maximum standardized uptake value to primary tumor size is a prognostic factor in patients with advanced non-small cell lung cancer

Fangfang Chen, Yanwen Yao, Chunyan Ma, Xingqun Ma, Zhaofeng Wang, Tangfeng Lv, Xinwu Xiao, Jie Yin, Yong Song

Advanced proton beam dosimetry part II: Monte Carlo vs. pencil beam-based planning for lung cancer

Dominic Maes, Jatinder Saini, Jing Zeng, Ramesh Rengan, Tony Wong, Stephen R. Bowen

The cytokinesis-blocked micronucleus assay as a novel biomarker for selection of lung cancer screening participants

Randa A. El-Zein, Carol J. Etzel, Reginald F. Munden

The use of TCP based EUD to rank and compare lung radiotherapy plans: in-silico study to evaluate the correlation between TCP with physical quality indices

Abdulhamid Chaikh, Jacques Balosso

Review Article

Beyond ALK-RET, ROS1 and other oncogene fusions in lung cancer

Takashi Kohno, Takashi Nakaoku, Koji Tsuta, Katsuya Tsuchihara, Shingo Matsumoto, Kiyotaka Yoh, Koichi Goto

Overview of clinicopathologic features of ALK-rearranged lung adenocarcinoma and current diagnostic testing for ALK rearrangement

Hyojin Kim, Jin-Haeng Chung

Neoadjuvant and adjuvant epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy for lung cancer

Haoran Zhai, Wenzhao Zhong, Xuening Yang, Yi-Long Wu

Known and putative mechanisms of resistance to EGFR targeted therapies in NSCLC patients with EGFR mutations—a review

Erin L. Stewart, Samuel Zhixing Tan, Geoffrey Liu, Ming-Sound Tsao

Clinical trials for lung cancer in China

Fei-Yu Niu, Wen-Zhao Zhong, Qing Zhou, Yi-Long Wu

Recurrence after surgery in patients with NSCLC

Hidetaka Uramoto, Fumihiro Tanaka

Prognostic markers in lung cancer: is it ready for prime time?

Chang-Qi Zhu, Ming-Sound Tsao

Potential biomarkers for lung cancer screening

Gabriella Sozzi, Mattia Boeri

Particle therapy in non-small cell lung cancer

Zhongxing Liao, Charles B. Simone II

Computer Aided Nodule Analysis and Risk Yield (CANARY) characterization of adenocarcinoma: radiologic biopsy, risk stratification and future directions

Ryan Clay, Srinivasan Rajagopalan, Ronald Karwoski, Fabien Maldonado, Tobias Peikert, Brian Bartholmai

Immunotherapy and radiation therapy for operable early stage and locally advanced non-small cell lung cancer

Neil K. Taunk, Andreas Rimner, Melissa Culligan, Joseph S. Friedberg, Julie Brahmer, Jamie Chaft

Combining immunotherapy and radiation therapy for small cell lung cancer and thymic tumors

Suchit H. Patel, Andreas Rimner, Roger B. Cohen

Intraoperative near-infrared imaging of mesothelioma

Gregory Thomas Kennedy, Andrew Newton, Jarrod Predina, Sunil Singhal

BAP1, a tumor suppressor gene driving malignant mesothelioma

Mitchell Cheung, Joseph R. Testa

Uncovering the immune tumor microenvironment in non-small cell lung cancer to understand response rates to checkpoint blockade and radiation

Jonathan E. Schoenhals, Steven N. Seyedin, Clark Anderson, Eric D. Brooks, Yun R. Li, Ahmed I. Younes, Sharareh Niknam, Ailin Li, Hampartsoum B. Barsoumian, Maria Angelica Cortez, James W. Welsh

Diagnostic and prognostic biomarkers for malignant mesothelioma: an update

Zhongjian Chen, Giovanni Gaudino, Harvey I. Pass, Michele Carbone, Haining Yang

Immunotherapy for malignant pleural mesothelioma: current status and future directions

Jordan Dozier, Hua Zheng, Prasad S. Adusumilli

Biology and clinical significance of circulating tumor cell subpopulations in lung cancer

Linda O’Flaherty, Harriet Wikman, Klaus Pantel

Routine clinical use of circulating tumor cells for diagnosis of mutations and chromosomal rearrangements in non-small cell lung cancer—ready for prime-time?

Emma Pailler, Vincent Faugeroux, Marianne Oulhen, Cyril Catelain, Françoise Farace

Challenges and unanswered questions for the next decade of circulating tumour cell research in lung cancer

Sumitra Mohan, Francesca Chemi, Ged Brady

Biophysical technologies for understanding circulating tumor cell biology and metastasis

Derrick W. Su, Jorge Nieva

Clinical utility of circulating tumor cells in patients with non-small-cell lung cancer

Marianna Gallo, Antonella De Luca, Monica Rosaria Maiello, Amelia D’Alessio, Claudia Esposito, Nicoletta Chicchinelli, Laura Forgione, Maria Carmela Piccirillo, Gaetano Rocco, Alessandro Morabito, Gerardo Botti, Nicola Normanno

Integrating immunotherapy into chemoradiation regimens for medically inoperable locally advanced non-small cell lung cancer

Salma K. Jabbour, Abigail T. Berman, Charles B. Simone II

Editorial

An alternative way to initiate Notch1 signaling in non-small cell lung cancer

Yi-Lin Yang, David Jablons, Liang You

Combination MET- and EGFR-directed therapy in MET-overexpressing non-small cell lung cancers: time to move on to better biomarkers?

Fernando C. Santini, Siddharth Kunte, Alexander Drilon

Systematic Review and Meta-analysis

Association of the metformin with the risk of lung cancer: a meta-analysis

Li Wang, Yong Song, Guan-Nan Wu, Dong-Mei Yuan

China Lung Cancer Research Highlight

Dll4/Notch1 signaling from tip/stalk endothelial cell specification to stroma-dependent lung tumor inhibition: a flavor of Dll4/Notch1 pleiotropy in tumor cell biology

Maria Felice Brizzi, Paola Defilippi

Editorials

Dulanermin in cancer therapy: Still much to do

Cristina Quintavalle, Gerolama Condorelli

Review Articles

EGFR molecular testing in African-American non-small cell lung cancer patients - a review of discrepant data

Bradley T. Clifford, Pingfu Fu, Nathan A. Pennell, Balazs Halmos, Rom S. Leidner

Copy number gains of FGFR1 and 3q chromosome in squamous cell carcinoma of the lung

Pedro Mendez, Jose Luis Ramirez

Role of HGF/MET axis in resistance of lung cancer to contemporary management

Kanwal Pratap Singh Raghav, Ana Maria Gonzalez-Angulo, George R. Blumenschein Jr

Circulating soluble intercellular adhesion Molecule-1 in lung cancer: a systematic review

Xiaoling Gu, Chunyan Ma, Dongmei Yuan, Yong Song

Ceritinib

Clinical development and approval of second generation ALK inhibitors for ALK rearranged lung cancer

Daniel B. Costa

Onartuzumab plus erlotinib

Targeting MET in NSCLC: looking for a needle in a haystack

Lorenza Landi, Federico Cappuzzo

Nivolumab

Nivolumab (anti-PD-1, BMS-936558, ONO-4538) in patients with advanced non-small cell lung cancer

Arun Rajan, James L. Gulley

Brief Report

The role of Imaging and Radiation Oncology Core for precision medicine era of clinical trial

Ying Xiao, Mark Rosen

Review Article on Update on Pathology and Predictive Biomarkers of Lung Cancer

Biology of invasive mucinous adenocarcinoma of the lung

Yoon Jin Cha, Hyo Sup Shim

Immunohistochemistry for predictive biomarkers in non-small cell lung cancer

Mari Mino- Kenudson

Below are the latest Translational Lung Cancer Research articles published online ahead of print publication.

Case Report

Pathological complete response and long-term survival by pembrolizumab based immunochemotherapy in epidermal growth factor receptor mutated non-small cell lung cancer post-tyrosine kinase inhibitor failure: a case report and tumor microenvironment analysis

Sangtian Liu, Wenhua Liang, Shicui Quan, Qilin Deng, Wenhai Fu, Yalei Zhang, Hong Du, Jianxing He

Published online: 23 March 2025

Original Article

Neoadjuvant immunochemotherapy demonstrated improved efficacy and comparable safety to neoadjuvant chemotherapy for limited-stage small-cell lung cancer: a cohort study

Lijiang Song, Xiaowei Mao, Haichuan Hu, Hu Zhang, Xinxin Ying, Lichen Zhang, Kai Liu, Huiyong Han, Dongde Li, Zhengfu He

Published online: 21 March 2025

Original Article

Analysis of baseline interstitial lung abnormality on the risk of checkpoint inhibitor-related pneumonitis and survival in advanced non-small cell lung cancer patients treated with first-line PD-1/PD-L1 inhibitors

Yu Li, Shuo Liang, Yanjun Du, Jun Yao, Yuxin Jiang, Wanjun Lu, Qiuxia Wu, Fumihiro Yamaguchi, Marko Jakopović, Wolfgang M. Brueckl, Dong Wang, Fang Zhang, Qin Wang, Tangfeng Lv, Ping Zhan

Published online: 20 March 2025

Original Article

Amivantamab as a salvage therapy post-EGFR-tyrosine kinase inhibitor failure in patients with mutated EGFR non-small cell lung cancer

Bilal Krayim, Waleed Kian, Maria Spector, Inbal Granot, Julia Dudnik, Michal Nissim, Dolev Kahala, Areen Abu Remilah, Naama R. Bogot, Gleb Kornev, Noam Asna, Nir Peled, Laila C. Roisman

Published online: 20 March 2025

Original Article

Connecting the dots: (RANKL⁺) extracellular vesicle count in blood plasma in relation to bone metastases, skeletal related events and osimertinib treatment in patients with EGFR mutated non-small cell lung cancer

Anita J. W. M. Brouns, Iris J. Robbesom-van den Berge, Sophie M. Ernst, Christi M. J. Steendam, Wouter W. Woud, Liang Wu, Anne-Marie C. Dingemans, Lizza E. L. Hendriks, Marjolein van Driel

Published online: 19 March 2025

Original Article

Prognostic significance of neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in second-line immunotherapy for patients with non-small cell lung cancer

Magdalena Knetki-Wróblewska, Aleksandra Grzywna, Paweł Krawczyk, Kamila Wojas-Krawczyk, Izabela Chmielewska, Tomasz Jankowski, Janusz Milanowski, Maciej Krzakowski

Published online: 18 March 2025

Original Article

Integrated multiomics machine learning and mediated Mendelian randomization investigate the molecular subtypes and prognosis lung squamous cell carcinoma

Zhanghao Huang, Jing Li, You Lang Zhou, Jiahai Shi

Published online: 18 March 2025

Original Article

Diagnostic utility of bronchoscopy for newly emerging peripheral pulmonary lesions after pulmonary resection

Takahiro Suzuki, Yuji Matsumoto, Hideaki Furuse, Keigo Uchimura, Tatsuya Imabayashi, Takaaki Tsuchida

Published online: 18 March 2025

Case Report

Metachronous development of L858R and T790M EGFR mutations following ALK inhibitor therapy in stage IV lung adenocarcinoma: a case report

So-Yun Kim, Jisoo Lee, Dongil Park, Jeong Eun Lee, Joo-Eun Lee, Hyun-Yi Kim, Da Hyun Kang, Chaeuk Chung

Published online: 18 March 2025

Original Article

Predicting survival in small cell lung cancer patients undergoing various treatments: a machine learning approach

Ziran Zhao, Xi Cheng, Yibo Gao, Fengwei Tan, Qi Xue, Shugeng Gao, Jie He

Published online: 14 March 2025

Review Article

Multidisciplinary management of N2 stage III non-small cell lung cancer: opportunities and challenges for radiation oncology

Hongcheng Zhu, Daniel G. Schep, Marta Isolano, Piergiorgio Muriana, Sarayut L. Geater, Giulia Veronesi, Fangqiu Fu, Roberto Ferrara, Kuaile Zhao, Alexander V. Louie

Published online: 14 March 2025

Original Article

Short-term peri- and intra-tumoral CT radiomics to predict immunotherapy response in advanced non-small cell lung cancer

Ting Wang, Lei Chen, Xiao Bao, Zijuan Han, Zezhou Wang, Shengdong Nie, Yajia Gu, Jing Gong

Published online: 14 March 2025

Original Article

Circulating lung cancer exosomes damage the niche of intestinal stem cells

Ke Wang, Lu Xu, Jianhua Feng, Shubin Wang, Xi Wang, Junyi Zou, Zhenni Xu, Lingxiao Huang, Wenjun Jiang, Jin Zhou, Xudan Lei, Dengqun Liu

Published online: 10 March 2025

Original Article

ANKRD11 as a potential biomarker for brain metastasis from lung adenocarcinoma via cerebrospinal fluid liquid biopsy

Qinhong Sun, Peng Xing, Qinglin Wang, Zhijun Xia, Jianyu Li, Zhitong Li, Fancheng Meng, Tongyan Liu, Siwei Wang, Rong Yin

Published online: 03 March 2025

Journal Highlight more

Translational Lung Cancer Research is an international, peer-reviewed, open-access journal indexed by Science Citation Index Expanded (SCIE) and PubMed/PubMed Central, focusing on cutting-edge development on the transition from preclinical to clinical research, including but not limited to multimodality therapy, markers, imaging, tumor biology, pathology, chemoprevention, and technical advances related to lung cancer and relevant thoracic diseases.